<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>The main objective of the current trial was to investigate the impacts of tilapia diets supplemented with S-methylmethionine sulfonium chloride (MMSC) on the growth performance, feed efficiency, body analysis, blood biochemistry and regulation of myostatin (<italic>MSTN</italic>) and insulin-like growth factor-1 (<italic>IGF-1</italic>) genes of nile tilapia (<italic>Oreochromis niloticus</italic>). The experimental fish (<italic>n</italic>=180) weighing 22.4±0.17 g were allocated randomly into three equal groups in triplicate as follows; the control group received an un-supplemented diet; the other two groups received two different levels of MMSC (0.2 and 0.4 g/kg) for eight weeks. The obtained findings demonstrated that tilapia diets enriched with small dosages of MMSC considerably (P&lt;0.05) enhanced all assessed growth performance and feed efficiency indicators when compared with the control group. When compared to the control group, tilapia meals supplemented with 0.2 g MMSC significantly (P&lt;0.05 or 0.01) raised blood protein profile, particularly total protein and globulin levels. Contrarily, blood creatinine levels were significantly (P&lt;0.01) reduced in the group of tilapia fed diets containing MMSC (0.2 or 0.4 g/kg) compared to the group without receiving any supplementation. Whereas, fish body analysis showed higher significant increases in crude protein and ether extract levels (P&lt;0.01) as well as reduced ash content (P&lt;0.05) in the fish group that received lower MMSC doses in comparison to other treated and control groups. In addition, MMSC dietary supplementation significantly downregulated the expression of <italic>MSTN</italic> and upregulated IGF-1 mRNA expression compared with the control group. Additionally, both dosages of MMSC supplementation modestly enhanced the intestinal villus histomorphometric score indices with observed tall, thick, and various broad tips in comparison to the control group. In conclusion, it could be recommended that fish diets supplemented with 0.2 g MMSC per kg diet may promote the growth and general health status of Nile Tilapia.</p>
</abstract>

The main objective of the current trial was to investigate the impacts of tilapia diets supplemented with S-methylmethionine sulfonium chloride (MMSC) on the growth performance, feed efficiency, body analysis, blood biochemistry and regulation of myostatin (MSTN) and insulin-like growth factor-1 (IGF-1) genes of nile tilapia (Oreochromis niloticus). The experimental fish (n=180) weighing 22.4±0.17 g were allocated randomly into three equal groups in triplicate as follows; the control group received an un-supplemented diet; the other two groups received two different levels of MMSC (0.2 and 0.4 g/kg) for eight weeks. The obtained findings demonstrated that tilapia diets enriched with small dosages of MMSC considerably (P<0.05) enhanced all assessed growth performance and feed efficiency indicators when compared with the control group. When compared to the control group, tilapia meals supplemented with 0.2 g MMSC significantly (P<0.05 or 0.01) raised blood protein profile, particularly total protein and globulin levels. Contrarily, blood creatinine levels were significantly (P<0.01) reduced in the group of tilapia fed diets containing MMSC (0.2 or 0.4 g/kg) compared to the group without receiving any supplementation. Whereas, fish body analysis showed higher significant increases in crude protein and ether extract levels (P<0.01) as well as reduced ash content (P<0.05) in the fish group that received lower MMSC doses in comparison to other treated and control groups. In addition, MMSC dietary supplementation significantly downregulated the expression of MSTN and upregulated IGF-1 mRNA expression compared with the control group. Additionally, both dosages of MMSC supplementation modestly enhanced the intestinal villus histomorphometric score indices with observed tall, thick, and various broad tips in comparison to the control group. In conclusion, it could be recommended that fish diets supplemented with 0.2 g MMSC per kg diet may promote the growth and general health status of Nile Tilapia.

Dietary Effect of S-Methylmethionine Sulfonium Chloride on Growth, Serum Biochemical Parameters, Body Composition, and Expression of Some Related Genes in <italic>Oreochromis niloticus</italic>

Department of Fish Production, Faculty of Agriculture

Department of Biochemistry, Faculty of Veterinary Medicine

Department of Aquaculture, Faculty of Aquatic and Fisheries Sciences

Department of Nutrition and Clinical Nutrition, Faculty of Veterinary Medicine

Department of Fish Health and Management, Sakha Aquaculture Research Unit

Department of Animal Production, Faculty of Agriculture

Annals of Animal Science

This work is licensed under the Creative Commons Attribution 4.0 International License.

Dietary Effect of S-Methylmethionine Sulfonium Chloride on Growth, Serum Biochemical Parameters, Body Composition, and Expression of Some Related Genes in 

The main objective of the current trial was to investigate the impacts of tilapia diets supplemented with S-methylmethionine sulfonium chloride (MMSC) on the...

Dietary Effect of S-Methylmethionine Sulfonium Chloride on Growth, Serum Biochemical Parameters, Body Composition, and Expression of Some Related Genes in Oreochromis niloticus

Pubblicato online: 23 gen 2024

Pagine: 151 - 160

Ricevuto: 10 dic 2022

Accettato: 04 mag 2023

DOI: https://doi.org/10.2478/aoas-2023-0059

Parole chiave
vitamin U, growth, performance, tilapia, intestinal structure, blood biochemical, myostatin

© 2024 Ahmed G.A. Gewida et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Dietary Effect of S-Methylmethionine Sulfonium Chloride on Growth, Serum Biochemical Parameters, Body Composition, and Expression of Some Related Genes in Oreochromis niloticus

Pubblicato online: 23 gen 2024

Pagine: 151 - 160

Ricevuto: 10 dic 2022

Accettato: 04 mag 2023

DOI: https://doi.org/10.2478/aoas-2023-0059

Parole chiavevitamin U, growth, performance, tilapia, intestinal structure, blood biochemical, myostatin

© 2024 Ahmed G.A. Gewida et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Parole chiave
vitamin U, growth, performance, tilapia, intestinal structure, blood biochemical, myostatin