This article combines the fractional differential theory with the total variation method and applies it to defining cultural industry image color matching. At the same time, we propose a new image color matching denoising model based on fractional partial differential equations. The model achieves simultaneous denoising in the time direction and the spaceplane. Experiments have proved that the fractional partial differential equations method has more advantages than integer-order partial differential equations in denoising and reducing step effects. It can effectively improve the contrast and clarity of image color matching in the cultural industry.