The article explores the evolution of regional spatial differences and has important practical significance for promoting the coordinated development of regional tourism. The article analyzes the characteristics of the spatial evolution of the economic tourism pattern from 2010 to 2020. The study found that the development of the regional tourism economy is on the rise, and the development is not balanced. The spatial self-organization of economic development is getting stronger and stronger, and the spatial economic distribution is different. Then this article analyzes the main factors that cause this spatial distribution and proposes corresponding solutions. This provides a theoretical basis for reducing the gap in the tourism economy between regions and promoting the coordinated development of the regional tourism economy.