<abstract xmlns="http://www.w3.org/1999/xhtml">

<bold>Objectives</bold>: Autoimmune gastritis (AG) is a rare condition that increases the risk of developing stomach adenocarcinomas or carcinoid tumours. The objectives of the present research were to summarise the clinical traits of AG patients, together with gastroscopic and histopatho-logic findings, demographic data, and hematologic characteristics.
<bold>Patients and methods</bold>: A medical centre assessed 58 AG patients from January 2019 to December 2022.
<bold>Results</bold>: The majority of the patients were female (73.7%), and the mean age of the participants at the time of the diagnosis was 57.7 ± 12.1 years. We identified pernicious anaemia (54.4%), iron deficiency anaemia (21.1%), as well as autoimmune disorders (96.5%). Though 78.9% of patients reported having gastrointestinal symptoms, 69% presented exclusively upper gastrointestinal symptoms, 17% only had lower, and 14% had concurrent upper and lower gastrointestinal symptoms. All 58 AG patients were examined for associated gastric lesions, although abnormal injuries were detected in only 22 of them. One patient (1.8%) had adenocarcinoma, while five patients (8.8%) had type 1 neuroendocrine tumours (NET). In addition, hyperplastic polyps were found in 16 (28.1%) individuals.
<bold>Conclusions</bold>: Other autoimmune diseases were present with AG, which showed a female predominance. Clinicians should give AG more significant thought by allowing access to interdisciplinary teams.
</abstract>

Objectives: Autoimmune gastritis (AG) is a rare condition that increases the risk of developing stomach adenocarcinomas or carcinoid tumours. The objectives of the present research were to summarise the clinical traits of AG patients, together with gastroscopic and histopatho-logic findings, demographic data, and hematologic characteristics.
Patients and methods: A medical centre assessed 58 AG patients from January 2019 to December 2022.
Results: The majority of the patients were female (73.7%), and the mean age of the participants at the time of the diagnosis was 57.7 ± 12.1 years. We identified pernicious anaemia (54.4%), iron deficiency anaemia (21.1%), as well as autoimmune disorders (96.5%). Though 78.9% of patients reported having gastrointestinal symptoms, 69% presented exclusively upper gastrointestinal symptoms, 17% only had lower, and 14% had concurrent upper and lower gastrointestinal symptoms. All 58 AG patients were examined for associated gastric lesions, although abnormal injuries were detected in only 22 of them. One patient (1.8%) had adenocarcinoma, while five patients (8.8%) had type 1 neuroendocrine tumours (NET). In addition, hyperplastic polyps were found in 16 (28.1%) individuals.
Conclusions: Other autoimmune diseases were present with AG, which showed a female predominance. Clinicians should give AG more significant thought by allowing access to interdisciplinary teams.

Clinical characteristics and endoscopic findings in autoimmune gastritis – A retrospective study

Acta Marisiensis - Seria Medica

This work is licensed under the Creative Commons Attribution 4.0 International License.

Objectives: Autoimmune gastritis (AG) is a rare condition that increases the risk of developing stomach adenocarcinomas or carcinoid tumours. The objectives of...

Clinical characteristics and endoscopic findings in autoimmune gastritis – A retrospective study

Pubblicato online: 29 mar 2023

Pagine: 61 - 67

Ricevuto: 26 gen 2022

Accettato: 02 mar 2023

DOI: https://doi.org/10.2478/amma-2023-0012

Parole chiave
autoimmune gastritis, iron/vitamin B12 deficiency, antiparietal cell antibody, multidisciplinary team

© 2023 Gabriella Gabos et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Clinical characteristics and endoscopic findings in autoimmune gastritis – A retrospective study

Pubblicato online: 29 mar 2023

Pagine: 61 - 67

Ricevuto: 26 gen 2022

Accettato: 02 mar 2023

DOI: https://doi.org/10.2478/amma-2023-0012

Parole chiaveautoimmune gastritis, iron/vitamin B12 deficiency, antiparietal cell antibody, multidisciplinary team

© 2023 Gabriella Gabos et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Parole chiave
autoimmune gastritis, iron/vitamin B12 deficiency, antiparietal cell antibody, multidisciplinary team