<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Sleep disorders can be the result of psychiatric or neurological conditions, such as post-traumatic stress disorders, depression, anxiety, Alzheimer’s disease, Parkinson’s disease. At the same time, changes in sleep, known as sleep disorders, are closely related to various metabolic dysfunctions, which in turn are the result of the generation of reactive oxygen species, or otherwise known as oxidative stress. For this reason, cannabinoid derivatives are increasingly used for this purpose. Among the most used are delta-9 tetrahydrocannabinol (THC) and cannabidiol (CBD). These agents interact with the endogenous endocannabinoid system, either by direct action on specific receptors, or by increasing the availability of endocannabinoids, modifying particular mental states (anxiety, depression). The results of the studies specified in this article provide promising evidence regarding the positive effects of CBD, which extend beyond the scope of sleep disorders, with possible applications also in the case of the accumulation of reactive oxygen species.</p>
</abstract>

Sleep disorders can be the result of psychiatric or neurological conditions, such as post-traumatic stress disorders, depression, anxiety, Alzheimer’s disease, Parkinson’s disease. At the same time, changes in sleep, known as sleep disorders, are closely related to various metabolic dysfunctions, which in turn are the result of the generation of reactive oxygen species, or otherwise known as oxidative stress. For this reason, cannabinoid derivatives are increasingly used for this purpose. Among the most used are delta-9 tetrahydrocannabinol (THC) and cannabidiol (CBD). These agents interact with the endogenous endocannabinoid system, either by direct action on specific receptors, or by increasing the availability of endocannabinoids, modifying particular mental states (anxiety, depression). The results of the studies specified in this article provide promising evidence regarding the positive effects of CBD, which extend beyond the scope of sleep disorders, with possible applications also in the case of the accumulation of reactive oxygen species.

Cannabidiol in the context of sleeping disorders-induced oxidative stress

George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures

Acta Marisiensis - Seria Medica

This work is licensed under the Creative Commons Attribution 4.0 International License.

{"article-title":"Cannabidiol in the context of sleeping disorders-induced oxidative stress"}

Sleep disorders can be the result of psychiatric or neurological conditions, such as post-traumatic stress disorders, depression, anxiety, Alzheimer’s disease,...

Cannabidiol in the context of sleeping disorders-induced oxidative stress

Pubblicato online: 07 gen 2023

Pagine: 150 - 153

Ricevuto: 29 ago 2022

Accettato: 08 set 2022

DOI: https://doi.org/10.2478/amma-2022-0023

Parole chiave
cannabidiol, tetrahydrocanabinol, oxidative stress, sleep, post-traumatic stress disorder

© 2022 George Jîtcă et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Cannabidiol in the context of sleeping disorders-induced oxidative stress

Pubblicato online: 07 gen 2023

Pagine: 150 - 153

Ricevuto: 29 ago 2022

Accettato: 08 set 2022

DOI: https://doi.org/10.2478/amma-2022-0023

Parole chiavecannabidiol, tetrahydrocanabinol, oxidative stress, sleep, post-traumatic stress disorder

© 2022 George Jîtcă et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Parole chiave
cannabidiol, tetrahydrocanabinol, oxidative stress, sleep, post-traumatic stress disorder