<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Loop-mediated isothermal amplification (LAMP) has received increased attention as a sensitive and fast molecular technique that could be applied at the site of need. The LAMP has been shown to specifically detect a variety of bacterial and viral infections as a promising point-of-care (POC) test. LAMP has recently demonstrated sensitivity and specificity comparable to or nearly equal to polymerase chain reaction in SARS-CoV-2 detection. The main advantages of LAMP are its application in low-income or remote areas where there are no specialized laboratories or molecular specialists. In the following mini-review we discuss the potential of LAMP as a POC molecular diagnostic method. Moreover, we summarized its validated application and future challenges.</p>
</abstract>

Loop-mediated isothermal amplification (LAMP) has received increased attention as a sensitive and fast molecular technique that could be applied at the site of need. The LAMP has been shown to specifically detect a variety of bacterial and viral infections as a promising point-of-care (POC) test. LAMP has recently demonstrated sensitivity and specificity comparable to or nearly equal to polymerase chain reaction in SARS-CoV-2 detection. The main advantages of LAMP are its application in low-income or remote areas where there are no specialized laboratories or molecular specialists. In the following mini-review we discuss the potential of LAMP as a POC molecular diagnostic method. Moreover, we summarized its validated application and future challenges.

Application of Lamp as a Point-of-Care Diagnostic Assay in Remote and Low-Income Regions: Mini-Review

Department of Medical Chemistry and Biochemistry

Acta Medica Bulgarica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Loop-mediated isothermal amplification (LAMP) has received increased attention as a sensitive and fast molecular technique that could be applied at the site of...

Application of Lamp as a Point-of-Care Diagnostic Assay in Remote and Low-Income Regions: Mini-Review

Pubblicato online: 23 giu 2024

Pagine: 53 - 57

Ricevuto: 14 mar 2023

Accettato: 28 lug 2023

DOI: https://doi.org/10.2478/amb-2024-0020

Parole chiave
LAMP, point-of-care, diagnostics

© 2024 M. E. Nikolova., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Application of Lamp as a Point-of-Care Diagnostic Assay in Remote and Low-Income Regions: Mini-Review

Pubblicato online: 23 giu 2024

Pagine: 53 - 57

Ricevuto: 14 mar 2023

Accettato: 28 lug 2023

DOI: https://doi.org/10.2478/amb-2024-0020

Parole chiaveLAMP, point-of-care, diagnostics

© 2024 M. E. Nikolova., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Parole chiave
LAMP, point-of-care, diagnostics