A New Case of Childhood Acute Lymphoblastic B-Cell Leukemia from Pristina
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22 mar 2023
INFORMAZIONI SU QUESTO ARTICOLO
Categoria dell'articolo: Case Report
Pubblicato online: 22 mar 2023
Pagine: 59 - 62
Ricevuto: 07 apr 2022
Accettato: 12 ago 2022
DOI: https://doi.org/10.2478/amb-2023-0009
Parole chiave
© 2023 V. Graiqevci-Uka et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Acute lymphoblastic leukemia (ALL) is a malignant disease caused by mutations in B- or T-cell precursors of bone marrow cells. Childhood acute lymphoblastic leukemia (ALL) is a subtype of pediatric cancer with a 1 in 2000 incidence. Here we present a new childhood ALL in a 3-year-old girl. As CD45/19, CD10/19, CD3, CD8, CD10, and CD19 were positive in immunohistochemically analyses of blast cells, a B-ALL was diagnosed with a causative ETV6-RUNX1 gene fusion. The patient was treated based on standard protocols BMF-ALL 2009. Interestingly, an aunt and a grandfather of the patient had experienced malignancies as well, which may be carefully interpreted as a hint on a familial cancer syndrome.