Molecular function | cytokine binding | GO:0019955 | 1.341E-17 | 11 |
cytokine receptor binding | GO:0005126 | 2.170E-17 | 13 | |
cytokine activity | GO:0005125 | 3.580E-15 | 11 | |
signalling receptor binding | GO:0005102 | 1.187E-11 | 16 | |
receptor ligand activity | GO:0048018 | 1.952E-11 | 11 | |
Biological process | inflammatory response | GO:0006954 | 4.830E-28 | 23 |
cytokine-mediated signalling pathway | GO:0019221 | 1.992E-25 | 19 | |
cellular response to cytokine stimulus | GO:0071345 | 1.277E-20 | 19 | |
response to cytokine | GO:0034097 | 9.706E-20 | 19 | |
leukocyte migration | GO:0050900 | 8.016E-19 | 15 | |
Pathway | KEGG cytokine receptor interaction | M9809 | 1.039E-30 | 20 |
reactome interleukin 10 signalling | M27605 | 6.459E-22 | 11 | |
reactome signalling by interleukins | M874 | 4.294E-18 | 16 | |
WP SARSCOV2 innate immunity evasion and cell-specific immune response | M40067 | 9.207E-18 | 10 | |
WP overview of proinflammatory and profibrotic mediators | M42533 | 1.091E-16 | 11 | |
Disease | susceptibility to HIV infection | 609423 | 6.577E-6 | 3 |
malaria, susceptibility to | cv:C1836230 | 6.577E-6 | 3 | |
white blood cell count quantitative trait locus 1 | 611162 | 5.893E-4 | 2 | |
WHIM syndrome 2 | cv:C1970028 | 5.893E-4 | 2 | |
Graft-versus-host disease, susceptibility to | 611862 | 2.333E-3 | 1 |
As | Expression of mRNA | N/A | ↓ | ↓↑ | ↑ | ↓ |
Protein expression | ↑ | ↑ | ↓↑ | ↑ | ↓↑ | |
Cd | Expression of mRNA | ↑ | ↓ | ↓↑ | ↓↑ | ↓↑ |
Protein expression | ↑ | ↑ | ↑ | ↑ | ↑ | |
Pb | Expression of mRNA | ↑ | N/A | ↑ | N/A | ↑ |
Protein expression | ↑ | ↓↑ | ↑ | ↑ | ↑ | |
Hg | Expression of mRNA | N/A | ↑ | ↑ | N/A | ↑ |
Protein expression | ↑ | N/A | ↑ | ↑ | ↑ | |
Ni | Expression of mRNA | ↑ | ↑ | ↑ | ↑ | ↑ |
Protein expression | ↑ | N/A | ↑ | ↑ | ↑ | |
Cr | Expression of mRNA | ↑ | N/A | N/A | N/A | ↑ |
Protein expression | N/A | N/A | N/A | ↓ | ↑ |
Arsenic (As) | 4997 | |
Cadmium (Cd) | 5281 | |
Lead (Pb) | 3278 | |
Mercury (Hg) | 635 | |
Nickel (Ni) | 7665 | |
Chromium (Cr) | 2353 | |