This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Castillo-Carniglia A, Keyes KM, Hasin DS, Cerdá M. Psychiatric comorbidities in alcohol use disorder. Lancet Psychiat 2019;6:1068–80. doi: 10.1016/S2215-0366(19)30222-6Castillo-CarnigliaAKeyesKMHasinDSCerdáM. Psychiatric comorbidities in alcohol use disorder. Lancet Psychiat2019;6:1068–80. doi: 10.1016/S2215-0366(19)30222-6Open DOISearch in Google Scholar
Degenhardt L, Charlson F, Ferrari A, Santomauro D, Erskine H, Mantilla-Herrara A, Whiteford H, Leung J, Naghavi M, Griswold M, Rehm J, Hall W, Sartorius B, Scott J, Vollset SE, Knudsen AK, Haro JM, Patton G, Kopec J, Carvalho Malta D, Topor-Madry R, McGrath J, Haagsma J, Allebeck P, Phillips M, Salomon J, Hay S, Foreman K, Lim S, Mokdad A, Smith M, Gakidou E, Murray C, Vos T. The global burden of disease attributable to alcohol and drug use in 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Psychiat 2018;5:987–1012. doi: 10.1016/S2215-0366(18)30337-7DegenhardtLCharlsonFFerrariASantomauroDErskineHMantilla-HerraraAWhitefordHLeungJNaghaviMGriswoldMRehmJHallWSartoriusBScottJVollsetSEKnudsenAKHaroJMPattonGKopecJCarvalho MaltaDTopor-MadryRMcGrathJHaagsmaJAllebeckPPhillipsMSalomonJHaySForemanKLimSMokdadASmithMGakidouEMurrayCVosT. The global burden of disease attributable to alcohol and drug use in 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Psychiat2018;5:987–1012. doi: 10.1016/S2215-0366(18)30337-7Open DOISearch in Google Scholar
Edenberg HJ, Foroud T. Genetics and alcoholism. Nat Rev Gastroenterol Hepatol 2013;10:487–94. doi: 10.1038/nrgastro.2013.86EdenbergHJForoudT. Genetics and alcoholism. Nat Rev Gastroenterol Hepatol2013;10:487–94. doi: 10.1038/nrgastro.2013.86Open DOISearch in Google Scholar
Heath AC, Whitfield JB, Martin NG, Pergadia ML, Goate AM, Lind PA, McEvoy BP, Schrage AJ, Grant JD, Chou YL, Zhu R, Henders AK, Medland SE, Gordon SD, Nelson EC, Agrawal A, Nyholt DR, Bucholz KK, Madden PA, Montgomery GW. A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications. Biol Psychiatry 2012;70:513–8. doi: 10.1016/j.biopsych.2011.02.028HeathACWhitfieldJBMartinNGPergadiaMLGoateAMLindPAMcEvoyBPSchrageAJGrantJDChouYLZhuRHendersAKMedlandSEGordonSDNelsonECAgrawalANyholtDRBucholzKKMaddenPAMontgomeryGW. A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications. Biol Psychiatry2012;70:513–8. doi: 10.1016/j.biopsych.2011.02.028Open DOISearch in Google Scholar
Deak JD, Miller AP, Gizer IR. Genetics of alcohol use disorder: a review. Curr Opin Psychol 2019;27:56–61. doi: 10.1016/j.copsyc.2018.07.012DeakJDMillerAPGizerIR. Genetics of alcohol use disorder: a review. Curr Opin Psychol2019;27:56–61. doi: 10.1016/j.copsyc.2018.07.012Open DOISearch in Google Scholar
Zhou H, Kalayasiri R, Sun Y, Nuñez YZ, Deng HW, Chen XD, Justice AC, Kranzler HR, Chang S, Lu L, Shi J, Sanichwankul K, Mutirangura A, Malison RT, Gelernter J. Genome-wide meta-analysis of alcohol use disorder in East Asians. Neuropsychopharmacology 2022;47:1791–7. doi: 10.1038/s41386-022-01265-wZhouHKalayasiriRSunYNuñezYZDengHWChenXDJusticeACKranzlerHRChangSLuLShiJSanichwankulKMutiranguraAMalisonRTGelernterJ. Genome-wide meta-analysis of alcohol use disorder in East Asians. Neuropsychopharmacology2022;47:1791–7. doi: 10.1038/s41386-022-01265-wOpen DOISearch in Google Scholar
Deak JD, Levey DF, Wendt FR, Zhou H, Galimberti M, Kranzler HR, Gaziano JM, Stein MB, Polimanti R, Gelernter J; Million Veteran Program. Genome-wide investigation of maximum habitual alcohol intake in US Veterans in relation to alcohol consumption traits and alcohol use disorder. JAMA Netw Open 2022;5(10):e2238880. doi: 10.1001/jamanetworkopen.2022.38880DeakJDLeveyDFWendtFRZhouHGalimbertiMKranzlerHRGazianoJMSteinMBPolimantiRGelernterJMillion Veteran Program. Genome-wide investigation of maximum habitual alcohol intake in US Veterans in relation to alcohol consumption traits and alcohol use disorder. JAMA Netw Open2022;5(10):e2238880. doi: 10.1001/jamanetworkopen.2022.38880Open DOISearch in Google Scholar
Zhou H, Sealock JM, Sanchez-Roige S, Clarke TK, Levey DF, Cheng Z, Li B, Polimanti R, Kember RL, Smith RV, Thygesen JH, Morgan MY, Atkinson SR, Thursz MR, Nyegaard M, Mattheisen M, Børglum AD, Johnson EC, Justice AC, Palmer AA, McQuillin A, Davis LK, Edenberg HJ, Agrawal A, Kranzler HR, Gelernter J. Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits. Nat Neurosci 2020;23:809–18. doi: 10.1038/s41593-020-0643-5ZhouHSealockJMSanchez-RoigeSClarkeTKLeveyDFChengZLiBPolimantiRKemberRLSmithRVThygesenJHMorganMYAtkinsonSRThurszMRNyegaardMMattheisenMBørglumADJohnsonECJusticeACPalmerAAMcQuillinADavisLKEdenbergHJAgrawalAKranzlerHRGelernterJ. Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits. Nat Neurosci2020;23:809–18. doi: 10.1038/s41593-020-0643-5Open DOISearch in Google Scholar
Sahni S, Tickoo M, Gupta R, Vaswani M, Ambekar A, Grover T, Sharma A. Association of serotonin and GABA pathway gene polymorphisms with alcohol dependence: A preliminary study. Asian J Psychiatr 2019;39:169–73. doi: 10.1016/j.ajp.2018.04.023SahniSTickooMGuptaRVaswaniMAmbekarAGroverTSharmaA. Association of serotonin and GABA pathway gene polymorphisms with alcohol dependence: A preliminary study. Asian J Psychiatr2019;39:169–73. doi: 10.1016/j.ajp.2018.04.023Open DOISearch in Google Scholar
Gegenhuber JB, Weinland C, Kornhuber J, Muehle C, Lenz B. OPRM1 A118G and serum β-endorphin interact with sex and digit ratio (2D:4D) to influence risk and course of alcohol dependence. Eur Neuropsychopharm 2018;28:1418–28. doi: 10.1016/j.euroneuro.2018.09.002GegenhuberJBWeinlandCKornhuberJMuehleCLenzB. OPRM1 A118G and serum β-endorphin interact with sex and digit ratio (2D:4D) to influence risk and course of alcohol dependence. Eur Neuropsychopharm2018;28:1418–28. doi: 10.1016/j.euroneuro.2018.09.002Open DOISearch in Google Scholar
Rasheed H, Stamp LK, Dalbeth N, Merriman TR. Interaction of the GCKR and A1CF loci with alcohol consumption to influence the risk of gout. Arthritis Res Ther 2017;19(1):161. doi: 10.1186/s13075-017-1369-yRasheedHStampLKDalbethNMerrimanTR. Interaction of the GCKR and A1CF loci with alcohol consumption to influence the risk of gout. Arthritis Res Ther2017;19(1):161. doi: 10.1186/s13075-017-1369-yOpen DOISearch in Google Scholar
Legaki E, Tsaklakidou D, Hatzimanolis A, Segredou E, Petalotis M, Moularogiorgou G, Mouchtouri V, Lykouras L, Stefanis NC, Gazouli M. Association of alcohol use disorder risk with ADH1B, DRD2, FAAH, SLC39A8, GCKR, and PDYN genetic polymorphisms. In Vivo 2022;36:2092–104. doi: 10.21873/invivo.1293LegakiETsaklakidouDHatzimanolisASegredouEPetalotisMMoularogiorgouGMouchtouriVLykourasLStefanisNCGazouliM. Association of alcohol use disorder risk with ADH1B, DRD2, FAAH, SLC39A8, GCKR, and PDYN genetic polymorphisms. In Vivo2022;36:2092–104. doi: 10.21873/invivo.1293Open DOISearch in Google Scholar
Panduro A, Ramos-Lopez O, Campollo O, Zepeda-Carrillo EA, Gonzalez-Aldaco K, Torres-Valadez R, Roman S. High frequency of the DRD2/ANKK1 A1 allele in Mexican Native Amerindians and Mestizos and its association with alcohol consumption. Drug Alcohol Depend 2017;172:66–72. doi: 10.1016/j.drugalcdep.2016.12.006PanduroARamos-LopezOCampolloOZepeda-CarrilloEAGonzalez-AldacoKTorres-ValadezRRomanS. High frequency of the DRD2/ANKK1 A1 allele in Mexican Native Amerindians and Mestizos and its association with alcohol consumption. Drug Alcohol Depend2017;172:66–72. doi: 10.1016/j.drugalcdep.2016.12.006Open DOISearch in Google Scholar
Vasconcelos ACCG, Neto E de SR, Pinto GR, Yoshioka FKN, Motta FJN, Vasconcelos DFP, Canalle R. Association study of the SLC6A3 VNTR (DAT) and DRD2/ANKK1 Taq1A polymorphisms with alcohol dependence in a population from Northeastern Brazil. Alcohol Clin Exp Res 2015;39:205–11. doi: 10.1111/acer.12625VasconcelosACCGNetoE de SRPintoGRYoshiokaFKNMottaFJNVasconcelosDFPCanalleR. Association study of the SLC6A3 VNTR (DAT) and DRD2/ANKK1 Taq1A polymorphisms with alcohol dependence in a population from Northeastern Brazil. Alcohol Clin Exp Res2015;39:205–11. doi: 10.1111/acer.12625Open DOISearch in Google Scholar
Preuss UW, Winham SJ, Biernacka JM, Geske JR, Bakalkin G, Koller G, Zill P, Soyka M, Karpyak VM. PDYN rs2281285 variant association with drinking to avoid emotional or somatic discomfort. PLoS One 2013;8(11):e78688. doi: 10.1371/journal.pone.0078688PreussUWWinhamSJBiernackaJMGeskeJRBakalkinGKollerGZillPSoykaMKarpyakVM. PDYN rs2281285 variant association with drinking to avoid emotional or somatic discomfort. PLoS One2013;8(11):e78688. doi: 10.1371/journal.pone.0078688Open DOISearch in Google Scholar
Banna FKE, Otto JM, Mulloy SM, Tsai W, McElroy SM, Wong AL, Zill P, Soyka M, Karpyak VM. Back-translating GWAS findings to animal models reveals a role for Hgfac and Slc39a8 in alcohol and nicotine consumption. Sci Rep 2022;12(1):9336. doi: 10.1038/s41598-022-13283-1BannaFKEOttoJMMulloySMTsaiWMcElroySMWongALZillPSoykaMKarpyakVM. Back-translating GWAS findings to animal models reveals a role for Hgfac and Slc39a8 in alcohol and nicotine consumption. Sci Rep2022;12(1):9336. doi: 10.1038/s41598-022-13283-1Open DOISearch in Google Scholar
Arends RM, Pasman JA, Verweij KJH, Derks EM, Gordon SD, Hickie I, Thomas NS, Aliev F, Zietsch BP, van der Zee MD, Mitchell BL, Martin NG, Dick DM, Gillespie NA, de Geus EJC, Boomsma DI, Schellekens AFA, Vink JM. Associations between the CADM2 gene, substance use, risky sexual behavior, and self-control: A phenome-wide association study. Addiction Biol 2021;26(6):e13015. doi: 10.1111/adb.13015ArendsRMPasmanJAVerweijKJHDerksEMGordonSDHickieIThomasNSAlievFZietschBPvan der ZeeMDMitchellBLMartinNGDickDMGillespieNAde GeusEJCBoomsmaDISchellekensAFAVinkJM. Associations between the CADM2 gene, substance use, risky sexual behavior, and self-control: A phenome-wide association study. Addiction Biol2021;26(6):e13015. doi: 10.1111/adb.13015Open DOISearch in Google Scholar
Konjevod M, Rešetar M, Matošić A, Čičin-Šain L, Štefulj J. Association of functional polymorphism in TPH2 gene with alcohol dependence and personality traits: Study in Cloninger’s type I and type II alcohol-dependent inpatients. Genes (Basel) 2023;14(2):413. doi: 10.3390/genes14020413KonjevodMRešetarMMatošićAČičin-ŠainLŠtefuljJ. Association of functional polymorphism in TPH2 gene with alcohol dependence and personality traits: Study in Cloninger’s type I and type II alcohol-dependent inpatients. Genes (Basel)2023;14(2):413. doi: 10.3390/genes14020413Open DOISearch in Google Scholar
Plemenitas A, Kastelic M, Porcelli S, Serretti A, Dolžan V, Kores Plesnicar B. Alcohol dependence and genetic variability in the serotonin pathway among currently and formerly alcohol-dependent males. Neuropsychobiology 2015;72:57–64. doi: 10.1159/000437432PlemenitasAKastelicMPorcelliSSerrettiADolžanVKores PlesnicarB. Alcohol dependence and genetic variability in the serotonin pathway among currently and formerly alcohol-dependent males. Neuropsychobiology2015;72:57–64. doi: 10.1159/000437432Open DOISearch in Google Scholar
Zhou H, Polimanti R, Yang BZ, Wang Q, Han S, Sherva R, Nuñez YZ, Zhao H, Farrer LA, Kranzler HR, Gelernter J. Genetic risk variants associated with comorbid alcohol dependence and major depression. JAMA Psychiatry 2017;74:1234–41. doi: 10.1001/jamapsychiatry.2017.3275ZhouHPolimantiRYangBZWangQHanSShervaRNuñezYZZhaoHFarrerLAKranzlerHRGelernterJ. Genetic risk variants associated with comorbid alcohol dependence and major depression. JAMA Psychiatry2017;74:1234–41. doi: 10.1001/jamapsychiatry.2017.3275Open DOISearch in Google Scholar
Gelernter J, Kranzler HR, Sherva R, Almasy L, Koesterer R, Smith AH, Anton R, Preuss UW, Ridinger M, Rujescu D, Wodarz N, Zill P, Zhao H, Farrer LA. Genome-wide association study of alcohol dependence: significant findings in African- and European-Americans including novel risk loci. Mol Psychiatry 2014;19:41–9. doi: 10.1038/mp.2013.145GelernterJKranzlerHRShervaRAlmasyLKoestererRSmithAHAntonRPreussUWRidingerMRujescuDWodarzNZillPZhaoHFarrerLA. Genome-wide association study of alcohol dependence: significant findings in African- and European-Americans including novel risk loci. Mol Psychiatry2014;19:41–9. doi: 10.1038/mp.2013.145Open DOISearch in Google Scholar
Nahorski MS, Asai M, Wakeling E, Parker A, Asai N, Canham N, Holder SE, Chen YC, Dyer J, Brady AF, Takahashi M, Woods CG. CCDC88A mutations cause PEHO-like syndrome in humans and mouse. Brain 2016;139:1036–44. doi: 10.1093/brain/aww014NahorskiMSAsaiMWakelingEParkerAAsaiNCanhamNHolderSEChenYCDyerJBradyAFTakahashiMWoodsCG. CCDC88A mutations cause PEHO-like syndrome in humans and mouse. Brain2016;139:1036–44. doi: 10.1093/brain/aww014Open DOISearch in Google Scholar
Enomoto A, Asai N, Namba T, Wang Y, Kato T, Tanaka M, Tatsumi H, Taya S, Tsuboi D, Kuroda K, Kaneko N, Sawamoto K, Miyamoto R, Jijiwa M, Murakumo Y, Sokabe M, Seki T, Kaibuchi K, Takahashi M. Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus. Neuron 2009;63:774–87. doi: 10.1016/j.neuron.2009.08.015EnomotoAAsaiNNambaTWangYKatoTTanakaMTatsumiHTayaSTsuboiDKurodaKKanekoNSawamotoKMiyamotoRJijiwaMMurakumoYSokabeMSekiTKaibuchiKTakahashiM. Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus. Neuron2009;63:774–87. doi: 10.1016/j.neuron.2009.08.015Open DOISearch in Google Scholar
Xie P, Kranzler HR, Krystal JH, Farrer LA, Zhao H, Gelernter J. Deep resequencing of 17 glutamate system genes identifies rare variants in DISC1 and GRIN2B affecting risk of opioid dependence. Addict Biol 2014;19:955–64. doi: 10.1111/adb.12072XiePKranzlerHRKrystalJHFarrerLAZhaoHGelernterJ. Deep resequencing of 17 glutamate system genes identifies rare variants in DISC1 and GRIN2B affecting risk of opioid dependence. Addict Biol2014;19:955–64. doi: 10.1111/adb.12072Open DOISearch in Google Scholar
Thomson PA, Parla JS, McRae AF, Kramer M, Ramakrishnan K, Yao J, Soares DC, McCarthy S, Morris SW, Cardone L, Cass S, Ghiban E, Hennah W, Evans KL, Rebolini D, Millar JK, Harris SE, Starr JM, MacIntyre J, Generation Scotland, McIntosh AM, Watson JD, Deary IJ, Visscher PM, Blackwood DH, McCombie WR, Porteous DJ. 708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits. Mol Psychiatry 2014;19:668–75. doi: 10.1038/mp.2013.68ThomsonPAParlaJSMcRaeAFKramerMRamakrishnanKYaoJSoaresDCMcCarthySMorrisSWCardoneLCassSGhibanEHennahWEvansKLReboliniDMillarJKHarrisSEStarrJMMacIntyreJGeneration ScotlandMcIntoshAMWatsonJDDearyIJVisscherPMBlackwoodDHMcCombieWRPorteousDJ. 708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits. Mol Psychiatry2014;19:668–75. doi: 10.1038/mp.2013.68Open DOISearch in Google Scholar
Wulaer B, Nagai T, Sobue A, Itoh N, Kuroda K, Nabeshima T, Yamada K. Repetitive and compulsive-like behaviors lead to cognitive dysfunction in Disc1∆2-3/∆2-3 mice. Genes Brain Behav 2018;17(8):e12478. doi: 10.1111/gbb.12478WulaerBNagaiTSobueAItohNKurodaKNabeshimaTYamadaK. Repetitive and compulsive-like behaviors lead to cognitive dysfunction in Disc1∆2-3/∆2-3 mice. Genes Brain Behav2018;17(8):e12478. doi: 10.1111/gbb.12478Open DOISearch in Google Scholar
Kitamura T, Asai N, Enomoto A, Maeda K, Kato T, Ishida M, Jiang P, Watanabe T, Usukura J, Kondo T, Costantini F, Murohara T, Takahashi M. Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin. Nat Cell Biol 2008;10:329–37. doi: 10.1038/ncb1695KitamuraTAsaiNEnomotoAMaedaKKatoTIshidaMJiangPWatanabeTUsukuraJKondoTCostantiniFMuroharaTTakahashiM. Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin. Nat Cell Biol2008;10:329–37. doi: 10.1038/ncb1695Open DOISearch in Google Scholar
Warner-Schmidt JL, Duman RS. VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants. Proc Natl Acad Sci U S A 2007;104:4647–52. doi: 10.1073/pnas.0610282104Warner-SchmidtJLDumanRS. VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants. Proc Natl Acad Sci U S A2007;104:4647–52. doi: 10.1073/pnas.0610282104Open DOISearch in Google Scholar
Shabani A, Masoumian S, Zamirinejad S, Hejri M, Pirmorad T, Yaghmaeezadeh H. Psychometric properties of Structured Clinical Interview for DSM-5 Disorders-Clinician Version (SCID-5-CV). Brain Behav 2021;11(5):e01894. doi: 10.1002/brb3.1894ShabaniAMasoumianSZamirinejadSHejriMPirmoradTYaghmaeezadehH. Psychometric properties of Structured Clinical Interview for DSM-5 Disorders-Clinician Version (SCID-5-CV). Brain Behav2021;11(5):e01894. doi: 10.1002/brb3.1894Open DOISearch in Google Scholar
Hamilton M. A rating scale for depression. J Neurol Neosurg Psychiat 1960;23:56–62. doi: 10.1136/jnnp.23.1.56HamiltonM. A rating scale for depression. J Neurol Neosurg Psychiat1960;23:56–62. doi: 10.1136/jnnp.23.1.56Open DOISearch in Google Scholar
Center for Statistical Genetics. CaTS - Power Calculator for Two Stage Association Studies [displayed 18 May 2023]. Available at http://csg. sph.umich.edu/abecasis/cats/Center for Statistical Genetics. CaTS - Power Calculator for Two Stage Association Studies[displayed 18 May 2023]. Available at http://csg. sph.umich.edu/abecasis/cats/Search in Google Scholar
Skol AD, Scott LJ, Abecasis R, Boehnke M. Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies. Nat Genet 2006;38:209–13. doi: 10.1038/ng1706SkolADScottLJAbecasisRBoehnkeM. Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies. Nat Genet2006;38:209–13. doi: 10.1038/ng1706Open DOISearch in Google Scholar
Blumberg HP, Wang F, Chepenik LG, Kalmar JH, Edmiston E, Duman RS, Gelernter J. Influence of vascular endothelial growth factor variation on human hippocampus morphology. Biol Psychiatry 2008;64:901–3. doi: 10.1016/j.biopsych.2008.07.003BlumbergHPWangFChepenikLGKalmarJHEdmistonEDumanRSGelernterJ. Influence of vascular endothelial growth factor variation on human hippocampus morphology. Biol Psychiatry2008;64:901–3. doi: 10.1016/j.biopsych.2008.07.003Open DOISearch in Google Scholar
Roddy D, Farrell C, Doolin K, Roman E, Tozzi L, Frodl T, O’Keane V, O’Hanlon E. The hippocampus in depression: more than the sum of its parts? Advanced hippocampal substructure segmentation in depression. Biol Psychiatry 2019;85:487–97. doi: 10.1016/j.biopsych.2018.08.021RoddyDFarrellCDoolinKRomanETozziLFrodlTO’KeaneVO’HanlonE. The hippocampus in depression: more than the sum of its parts? Advanced hippocampal substructure segmentation in depression. Biol Psychiatry2019;85:487–97. doi: 10.1016/j.biopsych.2018.08.021Open DOISearch in Google Scholar
Volkow ND, Wiers CE, Shokri-kojori E, Tomasi D, Wang GJ, Baler R. Neurochemical and metabolic effects of acute and chronic alcohol in the human brain: Studies with positron emission tomography. Neuropharmacology 2017;122:175–88. doi: 10.1016/j.neuropharm.2017.01.012VolkowNDWiersCEShokri-kojoriETomasiDWangGJBalerR. Neurochemical and metabolic effects of acute and chronic alcohol in the human brain: Studies with positron emission tomography. Neuropharmacology2017;122:175–88. doi: 10.1016/j.neuropharm.2017.01.012Open DOISearch in Google Scholar
Andersen AM, Pietrzak RH, Kranzler HR, Ma L, Zhou H, Liu X, Kramer J, Kuperman S, Edenberg HJ, Nurnberger JI Jr, Rice JP, Tischfield JA, Goate A, Foroud TM, Meyers JL, Porjesz B, Dick DM, Hesselbrock V, Boerwinkle E, Southwick SM, Krystal JH, Weissman MM, Levinson DF, Potash JB, Gelernter J, Han S. Polygenic scores for major depressive disorder and risk of alcohol dependence. JAMA Psychiatry 2017;74:1153–60. doi: 10.1001/jamapsychiatry.2017.2269AndersenAMPietrzakRHKranzlerHRMaLZhouHLiuXKramerJKupermanSEdenbergHJNurnbergerJIJrRiceJPTischfieldJAGoateAForoudTMMeyersJLPorjeszBDickDMHesselbrockVBoerwinkleESouthwickSMKrystalJHWeissmanMMLevinsonDFPotashJBGelernterJHanS. Polygenic scores for major depressive disorder and risk of alcohol dependence. JAMA Psychiatry2017;74:1153–60. doi: 10.1001/jamapsychiatry.2017.2269Open DOISearch in Google Scholar
Martinez P, Neupane SP, Perlestenbakken B, Toutoungi C, Bramness JG. The association between alcohol use and depressive symptoms across socioeconomic status among 40- and 45-year-old Norwegian adults. BMC Public Health 2015;15(1):1146. doi: 10.1186/s12889-015-2479-6MartinezPNeupaneSPPerlestenbakkenBToutoungiCBramnessJG. The association between alcohol use and depressive symptoms across socioeconomic status among 40- and 45-year-old Norwegian adults. BMC Public Health2015;15(1):1146. doi: 10.1186/s12889-015-2479-6Open DOISearch in Google Scholar
Dinescu D, Turkheimer E, Beam CR, Horn EE, Duncan G, Emery RE. Is marriage a buzzkill ? A twin study of marital status and alcohol consumption. J Fam Psychol 2016;30:698–707. doi: 10.1037/fam0000221DinescuDTurkheimerEBeamCRHornEEDuncanGEmeryRE. Is marriage a buzzkill ? A twin study of marital status and alcohol consumption. J Fam Psychol2016;30:698–707. doi: 10.1037/fam0000221Open DOISearch in Google Scholar
Bulloch AGM, Williams JVA, Lavorato DH, Patten SB. The depression and marital status relationship is modified by both age and gender. J Affect Disord 2017;223:65–8. doi: 10.1016/j.jad.2017.06.007BullochAGMWilliamsJVALavoratoDHPattenSB. The depression and marital status relationship is modified by both age and gender. J Affect Disord2017;223:65–8. doi: 10.1016/j.jad.2017.06.007Open DOISearch in Google Scholar
Mueller T, Lavori P, Keller M, Swartz A, Warshaw M, Hasin D, Coryell W, Endicott J, Rice J, Akiskal H. Prognostic effect of the variable course of alcoholism on the 10-year course of depression. Am J Psychiatry 1994;151:701–6. doi: 10.1176/ajp.151.5.701MuellerTLavoriPKellerMSwartzAWarshawMHasinDCoryellWEndicottJRiceJAkiskalH. Prognostic effect of the variable course of alcoholism on the 10-year course of depression. Am J Psychiatry1994;151:701–6. doi: 10.1176/ajp.151.5.701Open DOISearch in Google Scholar
Grittner U, Kuntsche S, Gmel G, Bloomfield K. Alcohol consumption and social inequality at the individual and country levels - Results from an international study. Eur J Public Health 2013;23:332–9. doi: 10.1093/eurpub/cks044GrittnerUKuntscheSGmelGBloomfieldK. Alcohol consumption and social inequality at the individual and country levels - Results from an international study. Eur J Public Health2013;23:332–9. doi: 10.1093/eurpub/cks044Open DOISearch in Google Scholar
, , e | 26 giu 2023