Bovine Lung Peptides after Trypsinolysis Reveal Anti-Exudative Activity

[1] Angelova H, Krumova E, Dzhambazova E, Pechlivanova D. Effects of the antinociceptive dipeptide L-tyrosine-L-arginine (kyotorphin) on the motivation, anxiety, and memory in rats. Folia Med (Plovdiv). 2021;63(2):189–196. AngelovaH KrumovaE DzhambazovaE PechlivanovaD Effects of the antinociceptive dipeptide L-tyrosine-L-arginine (kyotorphin) on the motivation, anxiety, and memory in rats Folia Med (Plovdiv) 2021 63 2 189 196 Search in Google Scholar

[2] Ao J, Li B. Amino acid composition and antioxidant activities of hydrolysates and peptide fractions from porcine collagen. Food Sci Technol Int. 2012;18(5):425–434. AoJ LiB Amino acid composition and antioxidant activities of hydrolysates and peptide fractions from porcine collagen Food Sci Technol Int 2012 18 5 425 434 Search in Google Scholar

[3] Azevedo Ade O, Campos JJ, de Souza GG, et al. Antinociceptive and anti-inflammatory effects of myricetin 3-O-β-galactoside isolated from Davilla elliptica: Involvement of the nitrergic system. J Nat Med. 2015;69(4):487–493. Azevedo AdeO CamposJJ de SouzaGG Antinociceptive and anti-inflammatory effects of myricetin 3-O-β-galactoside isolated from Davilla elliptica: Involvement of the nitrergic system J Nat Med 2015 69 4 487 493 Search in Google Scholar

[4] Bamdad F, Shin SH, Suh JW, Nimalaratne C, Sunwoo H. Anti-inflammatory and antioxidant properties of casein hydrolysate produced using high hydrostatic pressure combined with proteolytic enzymes. Molecules. 2017;22(4):609. BamdadF ShinSH SuhJW NimalaratneC SunwooH Anti-inflammatory and antioxidant properties of casein hydrolysate produced using high hydrostatic pressure combined with proteolytic enzymes Molecules 2017 22 4 609 Search in Google Scholar

[5] Ciubotaru I, Potempa LA, Wander RC. Production of modified C-reactive protein in U937-derived macrophages. Exp Biol Med (Maywood). 2005;230(10):762–770. CiubotaruI PotempaLA WanderRC Production of modified C-reactive protein in U937-derived macrophages Exp Biol Med (Maywood) 2005 230 10 762 770 Search in Google Scholar

[6] Couck e EM, Akbar H, Kahloon A, Lopez PP. Biliary Obstruction. StatPearls Publishing; St Petersburg, Florida, 2023. CouckeEM AkbarH KahloonA LopezPP Biliary Obstruction StatPearls Publishing St Petersburg, Florida 2023 Search in Google Scholar

[7] Cruz-Casas DE, Aguilar CN, Ascacio-Valdés JA, Rodríguez-Herrera R, Chávez-González ML, Flores-Gallegos AC. Enzymatic hydrolysis and microbial fermentation: The most favorable biotechnological methods for the release of bioactive peptides. Food Chem (Oxf). 2021;3:100047. Cruz-CasasDE AguilarCN Ascacio-ValdésJA Rodríguez-HerreraR Chávez-GonzálezML Flores-GallegosAC Enzymatic hydrolysis and microbial fermentation: The most favorable biotechnological methods for the release of bioactive peptides Food Chem (Oxf) 2021 3 100047 Search in Google Scholar

[8] Doig C, Seagar AL, Watt B, Forbes KJ. The efficacy of the heat killing of Mycobacterium tuberculosis. J Clin Pathol. 2002;55(10):778–779. DoigC SeagarAL WattB ForbesKJ The efficacy of the heat killing of Mycobacterium tuberculosis J Clin Pathol 2002 55 10 778 779 Search in Google Scholar

[9] Dong Y, Wen C, Li T, et al. The effects of amino acids on the gel properties of potassium iota carrageenan. Food Hydrocoll. 2019;95:378–384. DongY WenC LiT The effects of amino acids on the gel properties of potassium iota carrageenan Food Hydrocoll 2019 95 378 384 Search in Google Scholar

[10] Edwards AB, Mastaglia FL, Knuckey NW, Meloni BP. Neuroprotective cationic arginine-rich peptides (CARPs): An assessment of their clinical safety. Drug Saf. 2020;43(10):957–969. EdwardsAB MastagliaFL KnuckeyNW MeloniBP Neuroprotective cationic arginine-rich peptides (CARPs): An assessment of their clinical safety Drug Saf 2020 43 10 957 969 Search in Google Scholar

[11] Hembrom R, Roychaudhuri BK, Saha AK, et al. Evaluation of the validity of high serum antistreptolysin O titre only, as an indication for tonsillectomy. Indian J Otolaryngol Head Neck Surg. 2014;66(3):232–236. HembromR RoychaudhuriBK SahaAK Evaluation of the validity of high serum antistreptolysin O titre only, as an indication for tonsillectomy Indian J Otolaryngol Head Neck Surg 2014 66 3 232 236 Search in Google Scholar

[12] Ikarashi Y, Takahashi A, Ishimaru H, Shiobara T, Maruyama Y. The role of nitric oxide in striatal acetylcholine release induced by N-methyl-D-aspartate. Neurochem Int. 1998;33(3):255–261. IkarashiY TakahashiA IshimaruH ShiobaraT MaruyamaY The role of nitric oxide in striatal acetylcholine release induced by N-methyl-D-aspartate Neurochem Int 1998 33 3 255 261 Search in Google Scholar

[13] Iwata M, Suzuki S, Asai Y, Inoue T, Takagi K. Involvement of nitric oxide in a rat model of carrageenin-induced pleurisy. Mediators Inflamm. 2010;2010:682879. IwataM SuzukiS AsaiY InoueT TakagiK Involvement of nitric oxide in a rat model of carrageenin-induced pleurisy Mediators Inflamm 2010 2010 682879 Search in Google Scholar

[14] Kaur K, Singh L, Kaur A, Bhatti R. Exploring the possible mechanism involved in the antinociceptive effect of β-sitosterol: Modulation of oxidative stress, nitric oxide and IL-6. Inflammopharmacology. 2023;31(1):517–527. KaurK SinghL KaurA BhattiR Exploring the possible mechanism involved in the antinociceptive effect of β-sitosterol: Modulation of oxidative stress, nitric oxide and IL-6 Inflammopharmacology 2023 31 1 517 527 Search in Google Scholar

[15] Kawabata A, Fukuzumi Y, Fukushima Y, Takagi H. Antinociceptive effect of L-arginine on the carrageenin-induced hyperalgesia of the rat: Possible involvement of central opioidergic systems. Eur J Pharmacol. 1992a;218(1):153–158. KawabataA FukuzumiY FukushimaY TakagiH Antinociceptive effect of L-arginine on the carrageenin-induced hyperalgesia of the rat: Possible involvement of central opioidergic systems Eur J Pharmacol 1992a 218 1 153 158 Search in Google Scholar

[16] Kawabata A, Nishimura Y, Takagi H. L-leucyl-L-arginine, naltrindole and D-arginine block antinociception elicited by L-arginine in mice with carrageenin-induced hyperalgesia. Br J Pharmacol. 1992b;107(4):1096–1101. KawabataA NishimuraY TakagiH L-leucyl-L-arginine, naltrindole and D-arginine block antinociception elicited by L-arginine in mice with carrageenin-induced hyperalgesia Br J Pharmacol 1992b 107 4 1096 1101 Search in Google Scholar

[17] Kiewiet MBG, Gros M, van Neerven RJJ, Faas MM, de Vos P. Immunomodulating properties of protein hydrolysates for application in cow’s milk allergy. Pediatr Allergy Immunol. 2015;26(3):206–217. KiewietMBG GrosM van NeervenRJJ FaasMM de VosP Immunomodulating properties of protein hydrolysates for application in cow’s milk allergy Pediatr Allergy Immunol 2015 26 3 206 217 Search in Google Scholar

[18] Kumar R, Gupta YK, Singh S. Anti-inflammatory and anti-granuloma activity of Berberis aristata DC. in experimental models of inflammation. Indian J Pharmacol. 2016;48(2):155–161. KumarR GuptaYK SinghS Anti-inflammatory and anti-granuloma activity of Berberis aristata DC. in experimental models of inflammation Indian J Pharmacol 2016 48 2 155 161 Search in Google Scholar

[19] Lundberg JO, Weitzberg E, Gladwin MT. The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics. Nat Rev Drug Discov. 2008;7:156–167. LundbergJO WeitzbergE GladwinMT The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics Nat Rev Drug Discov 2008 7 156 167 Search in Google Scholar

[20] McGovern AJ, Vitkovitsky IV, Jones DL, Mullins ME. Can AST/ALT ratio indicate recovery after acute paracetamol poisoning? Clin Toxicol (Phila). 2015;53(3):164–167. McGovernAJ VitkovitskyIV JonesDL MullinsME Can AST/ALT ratio indicate recovery after acute paracetamol poisoning? Clin Toxicol (Phila) 2015 53 3 164 167 Search in Google Scholar

[21] Ndiaye F, Vuong T, Duarte J, Aluko RE, Matar C. Anti-oxidant, anti-inflammatory and immunomodulating properties of an enzymatic protein hydrolysate from yellow field pea seeds. Eur J Nutr. 2012;51(1):29–37. NdiayeF VuongT DuarteJ AlukoRE MatarC Anti-oxidant, anti-inflammatory and immunomodulating properties of an enzymatic protein hydrolysate from yellow field pea seeds Eur J Nutr 2012 51 1 29 37 Search in Google Scholar

[22] Ngashangva L, Bachu V, Goswami P. Development of new methods for determination of bilirubin. J Pharm Biomed Anal. 2019;162:272–285. NgashangvaL BachuV GoswamiP Development of new methods for determination of bilirubin J Pharm Biomed Anal 2019 162 272 285 Search in Google Scholar

[23] Omote K, Hazama K, Kawamata T, et al. Peripheral nitric oxide in carrageenan-induced inflammation. Brain Res. 2001;912(2):171–175. OmoteK HazamaK KawamataT Peripheral nitric oxide in carrageenan-induced inflammation Brain Res 2001 912 2 171 175 Search in Google Scholar

[24] O’Sullivan S, Lafarga T, Hayes M, O’Brien NM. Bioactivity of bovine lung hydrolysates prepared using papain, pepsin, and Alcalase. J Food Biochem. 2017;41:e12406. O’SullivanS LafargaT HayesM O’BrienNM Bioactivity of bovine lung hydrolysates prepared using papain, pepsin, and Alcalase J Food Biochem 2017 41 e12406 Search in Google Scholar

[25] O’Sullivan S, Lafarga T, Hayes M, O’Brien NM. Potential bioactivity of hydrolysates derived from bovine lung. Proc Nutr Soc. 2016;75(OCE3):E168. O’SullivanS LafargaT HayesM O’BrienNM Potential bioactivity of hydrolysates derived from bovine lung Proc Nutr Soc 2016 75 OCE3 E168 Search in Google Scholar

[26] Otto-Ślusarczyk D, Graboń W, Mielczarek-Puta M. Aminotransferaza asparaginianowa – kluczowy enzym w metabolizmie ogólnoustrojowym człowieka [Aspartate aminotransferase – key enzyme in the human systemic metabolism]. Postepy Hig Med Dosw (Online). 2016;70:219–230. Otto-ŚlusarczykD GrabońW Mielczarek-PutaM Aminotransferaza asparaginianowa – kluczowy enzym w metabolizmie ogólnoustrojowym człowieka [Aspartate aminotransferase – key enzyme in the human systemic metabolism] Postepy Hig Med Dosw (Online) 2016 70 219 230 Search in Google Scholar

[27] Ozer J, Ratner M, Shaw M, Bailey W, Schomaker S. The current state of serum biomarkers of hepatotoxicity. Toxicology. 2008;245(3):194–205. OzerJ RatnerM ShawM BaileyW SchomakerS The current state of serum biomarkers of hepatotoxicity Toxicology 2008 245 3 194 205 Search in Google Scholar

[28] Park J, Mehrotra R, Rhee CM, et al. Serum creatinine level, a surrogate of muscle mass, predicts mortality in peritoneal dialysis patients. Nephrol Dial Transplant. 2013;28(8):2146–2155. ParkJ MehrotraR RheeCM Serum creatinine level, a surrogate of muscle mass, predicts mortality in peritoneal dialysis patients Nephrol Dial Transplant 2013 28 8 2146 2155 Search in Google Scholar

[29] Parlar A, Arslan SO, Çam SA. Glabridin alleviates inflammation and nociception in rodents by activating BK_Ca channels and reducing NO levels. Biol Pharm Bull. 2020;43(5):884–897. ParlarA ArslanSO ÇamSA Glabridin alleviates inflammation and nociception in rodents by activating BK_Ca channels and reducing NO levels Biol Pharm Bull 2020 43 5 884 897 Search in Google Scholar

[30] Payne E, Harrington K, Richard P, et al. Effects of vancomycin on persistent pain-stimulated and pain-depressed behaviors in female Fischer rats with or without voluntary access to running wheels. J Pain. 2021;22(11):1530–1544. PayneE HarringtonK RichardP Effects of vancomycin on persistent pain-stimulated and pain-depressed behaviors in female Fischer rats with or without voluntary access to running wheels J Pain 2021 22 11 1530 1544 Search in Google Scholar

[31] Rafter I, Gråberg T, Kotronen A, et al. Isoform-specific alanine aminotransferase measurement can distinguish hepatic from extrahepatic injury in humans. Int J Mol Med. 2012;30(5):1241–1249. RafterI GråbergT KotronenA Isoform-specific alanine aminotransferase measurement can distinguish hepatic from extrahepatic injury in humans Int J Mol Med 2012 30 5 1241 1249 Search in Google Scholar

[32] Ridker PM. Clinical application of C-reactive protein for cardiovascular disease detection and prevention. Circulation 2003;107(3):363–369. RidkerPM Clinical application of C-reactive protein for cardiovascular disease detection and prevention Circulation 2003 107 3 363 369 Search in Google Scholar

[33] Rivera-Jiménez J, Berraquero-García C, Pérez-Gálvez R, et al. Peptides and protein hydrolysates exhibiting anti-inflammatory activity: Sources, structural features and modulation mechanisms. Food Funct. 2022;13(24):12510–12540. Rivera-JiménezJ Berraquero-GarcíaC Pérez-GálvezR Peptides and protein hydrolysates exhibiting anti-inflammatory activity: Sources, structural features and modulation mechanisms Food Funct 2022 13 24 12510 12540 Search in Google Scholar

[34] Sproston NR, Ashworth JJ. Role of C-reactive protein at sites of inflammation and infection. Front Immunol. 2018;9:754. SprostonNR AshworthJJ Role of C-reactive protein at sites of inflammation and infection Front Immunol 2018 9 754 Search in Google Scholar

[35] van Dijk A, van Eldik M, Veldhuizen EJ, et al. Immunomodulatory and anti-inflammatory activities of chicken cathelicidin-2 derived peptides. PLoS One. 2016;11(2):e0147919. van DijkA van EldikM VeldhuizenEJ Immunomodulatory and anti-inflammatory activities of chicken cathelicidin-2 derived peptides PLoS One 2016 11 2 e0147919 Search in Google Scholar

[36] Washington IM, Van Hoosier G. Clinical biochemistry and hematology. The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents; Academic Press, London, UK, 2012, p. 57–116. WashingtonIM Van HoosierG Clinical biochemistry and hematology. The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents Academic Press London, UK 2012 57 116 Search in Google Scholar

[37] Yaren H, Mollaoglu H, Kurt B, et al. Lung toxicity of nitrogen mustard may be mediated by nitric oxide and peroxynitrite in rats. Res Vet Sci. 2007;83(1):116–122. YarenH MollaogluH KurtB Lung toxicity of nitrogen mustard may be mediated by nitric oxide and peroxynitrite in rats Res Vet Sci 2007 83 1 116 122 Search in Google Scholar

[38] Yuan L, Chu Q, Wu X, et al. Anti-inflammatory and antioxidant activity of peptides from ethanol-soluble hydrolysates of sturgeon (Acipenser schrenckii) cartilage. Front Nutr. 2021;8:689648. YuanL ChuQ WuX Anti-inflammatory and antioxidant activity of peptides from ethanol-soluble hydrolysates of sturgeon (Acipenser schrenckii) cartilage Front Nutr 2021 8 689648 Search in Google Scholar