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1. Yang F, Li ZL, Shan Q, Zeng ZL: Pharmacokinetics of doxycycline in tilapia (Oreochromis aureus x Oreochromis niloticus) after intravenous and oral administration. J Vet Pharmacol Ther 2014, 37: 388–393.Search in Google Scholar
2. Nguyen F, Starosta AL, Arenz S, Sohmen D, Dönhöfer A, Wilson DN: Tetracycline antibiotics and resistance mechanisms. Biol Chem 2014, 395: 559–575.Search in Google Scholar
3. Cunha BA, Sibley CM, Ristuccia AM: Doxycycline. Ther Drug Monit 1982, 4(2):115-35.Search in Google Scholar
4. Riond JL, Riviere JE: Pharmacology and toxicology of doxycycline. Vet Hum Toxicol 1988, 30(5): 431-43.Search in Google Scholar
5. Saivin S, Houin G: Clinical pharmacokinetics of doxycycline and minocycline. Clin Pharmacokinet 1988, 15: 355–366.Search in Google Scholar
6. Jha VK, Jayachandran C, Singh MK, Singh SD: Pharmacokinetic data on doxycycline and its distribution in different biological fluids in female goats. Vet Res Commun 1989, 13(1): 11-6.Search in Google Scholar
7. Mapenay I, Mitema E, Maitho T: Aspects of the pharmacokinetics of doxycycline given to healthy and pneumonic East African dwarf goats by intramuscular injection. Vet Res Commun 1997, 21: 453–462.Search in Google Scholar
8. El-Aty AA, Goudah A, Zhou HH: Pharmacokinetics of doxycycline after administration as a single intravenous bolus and intramuscular doses to non-lactating Egyptian goats. Pharmacol Res 2004, 49: 487–491.Search in Google Scholar
9. Vargas D, Gutierrez L, Juárez I, Gonzalez F, Sumano H: Pharmacokinetics after administration of an injectable experimental long-acting parenteral formulation of doxycycline hyclate in goats. Am J Vet Res 2008, 69: 1085–1090.Search in Google Scholar
10. Krishna AC, Sathiyaraj M, Saravanan RS, Chelladurai R, Vignesh R: A Novel and Rapid Method to Determine Doxycycline in Human Plasma by Liquid Chromatography Tandem Mass Spectrometry. Indian J Pharm Sci 2012, 74(6): 541–548.Search in Google Scholar
11. Permana AD, Tekko IA, McCarthy HO, Donnelly RF: New HPLC-MS method for rapid and simultaneous quantification of doxycycline, diethylcarbamazine and albendazole metabolites in rat plasma and organs after concomitant oral administration. J Pharm Biomed Anal 2019, 170: 243-253.Search in Google Scholar
12. Petkova T, Yordanova A, Milanova A: Population Pharmacokinetics of Doxycycline, Administered Alone or with N-Acetylcysteine, in Chickens with Experimental Mycoplasma gallisepticum. Infection. Pharmaceutics 2022, 14: 2440.Search in Google Scholar
13. Baert K, Croubels S, Gasthuys F, De Busser J, De Backer P: Pharmacokinetics and oral bioavailability of a doxycycline formulation (Doxycycline 75%) in nonfasted young pigs. J Vet Pharmacol Ther 2000, 23: 45–48.Search in Google Scholar
14. Shariati S, Yamini Y, Esrafili A: Carrier mediated hollow fiber liquid phase microextraction combined with HPLC-UV for preconcentration and determination of some tetracycline antibiotics. J Chromatogr Biomed Appl B 2009, 877: 393–400.Search in Google Scholar
15. Ramesh PJ, Basavaiah K, Tharpa K, Vinay KB, Revanasiddappa HD: Development and validation of RP-HPLC method for the determination of doxycycline hyclate in spiked human urine and pharmaceuticals. J Pre-Clin Clin Res 2010, 4: 101–107.Search in Google Scholar
16. Yang F, Yang F, Wang G, Kong T: Pharmacokinetics of doxycycline after oral administration of single and multiple dose in broiler chickens. J Vet Pharmacol Ther 2018, 41: 919–923.Search in Google Scholar
17. Turk E, Corum O, Tekeli IO, Sakin F, Uney K: Effects of Single and Repeated Doses on Disposition and Kinetics of Doxycycline Hyclate in Goats. Animals 2020, 10(6): 1088.Search in Google Scholar
18. Wang TL, Mei QS, Tao ZH, Wu HT, Zhao MY, Wang S, Liu YQ: A smartphone-integrated ratiometric fluorescence sensing platform for visual and quantitative point-of-care testing of tetracycline. Biosens Bioelectron 2020, 148: 111791.Search in Google Scholar
19. Croubels S, Vermeersch H, De Backer P, Santos MD, Remon JP, Van Peteghem C: Liquid chromatographic separation of doxycycline and 4-epidoxycycline in a tissue depletion study of doxycycline in turkeys. J Chromatogr B Biomed Sci Appl 1998, 708: 145-52.Search in Google Scholar
20. Wasch K, Okerman L, Croubels S, De Brabander H, Van Hoof J, De Backer P: Detection of residues of tetracycline antibiotics in pork and chicken meat: correlation between results of screening and confirmatory tests. Analyst 1998, 123(12): 2737-41.Search in Google Scholar
21. Denić MS, Sunarić SM, Kesić LG, Minić IZ, Obradović RR, Denić MS, Petrović MS: RP-HPLC assay of doxycycline in human saliva and gingival crevicular fluid in patients with chronic periodontal disease. J Pharm Biomed Anal 2013, 78-79: 170-5.Search in Google Scholar
22. Orlando EA, Simionato AV: Extraction of tetracyclinic antibiotic residues from fish filet: comparison and optimization of different procedures using liquid chromatography with fluorescence detection. J Chromatogr A 2013, 1307: 111-8.Search in Google Scholar
23. Wang X, Wang X: UiO-66-NH2 based fluorescent sensing for detection of tetracyclines in milk. RSC Adv 2022, 12(36): 23427-23436.Search in Google Scholar
24. Hernandis V, Escudero E, Marín P: A novel liquid chromatography-fluorescence method for the determination of delafloxacin in human plasma. J Sep Sci 2022, 45: 706–716.Search in Google Scholar
25. Food and Drug Administration 2018. Bioanalytical Method Validation – Guidance for Industry. US Department of Health and Human Services. Retrieved from https://www.fda.gov/files/drugs/published/Bioanalytical-Method-Validation-Guidance-for-Industry. pdfSearch in Google Scholar
26. Ruyck H, Ridder H: Determination of tetracycline antibiotics in cow’s milk by liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom 2017, 21(9): 1511-20.Search in Google Scholar
27. Alija G, Hajrulai-Musliu Z, Uzunov R: Development and validation of confirmatory LC–MS/MS method for multi-residue analysis of antibiotic drugs in bovine milk. SN Appl Sci 2020, 2: 1563.Search in Google Scholar
28. Zhou W, Yang S, Wang PG: Matrix effects and application of matrix effect factor. Bioanalysis 2017, 9(23): 1839-1844.Search in Google Scholar
29. Yang F, Si HB, Wang YQ, Zhao ZS, Zhou BH, Hao XQ: Pharmacokinetics of doxycycline in laying hens after intravenous and oral administration. Br Poult Sci 2016, 57: 576–580.Search in Google Scholar
30. Yang F, Sun N, Zhao ZS, Wang GY, Wang MF: Pharmacokinetics of doxycycline after a single intravenous, oral or intramuscular dose in Muscovy ducks (Cairina moschata). Br Poult Sci 2015, 56: 137–142.Search in Google Scholar
31. Yang F, Li GH, Meng XB, Wang LQ, Huang XH, Shan Q, Zeng DP, Ding HZ, Zeng ZL: Pharmacokinetic interactions of flunixin meglumine and doxycycline in broiler chickens. J Vet Pharmacol Ther 2013, 36: 85–88.Search in Google Scholar
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