Genotoxic Effects of Green Tea Extract on Human Laryngeal Carcinoma Cells In Vitro

Dixon RA, Steel CL. Flavonoids and isoflavonoids-a gold mine for metabolic engeenering. Trends Plant Sci 1999;4:394-400.10.1016/S1360-1385(99)01471-5Search in Google Scholar

De Flora S, Izzotti A, D'Agostini F, Balansky RM, Noonan D, Albini A. Multiple points of intervention in the prevention of cancer and other mutation-related diseases. Mutat Res 2001;480-481:9-22.10.1016/S0027-5107(01)00165-8Search in Google Scholar

Decker EA. Phenolics: prooxidants or antioxidants? Nutr Rev 1997;55:396-8.10.1111/j.1753-4887.1997.tb01580.xSearch in Google Scholar

Pietta PG. Flavonoids as antioxidants. J Nat Prod 2000;63:1035-42.10.1021/np9904509Search in Google Scholar

Aherne SA, O'Brien NM. Dietary flavonols: chemistry, food content and metabolism. Nutrition 2002;18:75-81.10.1016/S0899-9007(01)00695-5Search in Google Scholar

Breinholt V. Desirable versus harmful levels of intake of flavonoids and phenolic acids. In: Kumpulainen JT, Salonen JT, editors. Natural antioxidants and anticancerogens in nutrition, health and disease. London: The Royal Society of Chemistry; 1999. p. 100-10.10.1533/9781845698409.3.93Search in Google Scholar

Roderick HD. Frontiers in polyphenols and cancer prevention. J Nutr 2007;137(Suppl 1):267S-9S.10.1093/jn/137.1.267S17182838Search in Google Scholar

Chen D, Ping Dou Q. Tea polyphenols and their roles in cancer prevention and chemotherapy. Int J Mol Sci 2008;9:1196-206.10.3390/ijms9071196263571919325799Search in Google Scholar

Rusak G, Gutzeit HO, Müller JL. Effects of structurally related flavonoids on hsp gene expression in human promyeloid leukaemia cells. Food Technol Biotechnol 2002;40:267-73.Search in Google Scholar

Reiners JJ Jr, Clift R, Mathieu P. Suppresion of cell cycle progression by flavonoids; dependence on aryl hydrocarbon receptor. Carcinogenesis 1999;20:1561-6.10.1093/carcin/20.8.156110426807Search in Google Scholar

Plochmann K, Korte G, Koutsilieri E, Richling E, Riederer P, Rethwilm A, Schreier P, Scheller C. Structure-activity relationships of flavonoid-induced cytotoxicity on human leukemia cells. Arch Biochem Biophys 2007;460:1-9.10.1016/j.abb.2007.02.00317353006Search in Google Scholar

Osmak M, Nikšić D, Brozović A, Ambriović Ristov A, Vrhovec I, Škrk J. Drug resistant tumor cells have increased levels of tumor markers for invasion and metastasis. Anticancer Res 1999;19:3193-8.Search in Google Scholar

Brozović A, Fritz G, Christmann M, Zisowsky J, Jaehde U, Osmak M, Kaina B. Long-term activation of SAPK/JNK, p38 kinase and fas-L expression by cisplatin is attenuated in human carcinoma cells that aquired drug resistance. Int J Cancer 2004;112:974-85.10.1002/ijc.20522Search in Google Scholar

Brozović A, Šimaga Š, Osmak M. Induction of heat shock protein 70 in drug-resistant cells by anticancer drugs and hyperthermia. Neoplasma 2001;48:99-103.Search in Google Scholar

Čemažar M, Marolt D, Lavrič M, Serša G. Comparison of colorimetric MTT and clonogenic assays for irradiation and cisplatin treatment on murine fibrosarcoma SA-1 cells. Radiol Oncol 1999;33:303-8.Search in Google Scholar

Matsuo M, Sasaki N, Saga K, Kaneko T. Cytotoxicty of flavonoids toward cultured normal human cells. Biol Pharm Bull 2005;28:253-9.10.1248/bpb.28.253Search in Google Scholar

Cereser C, Boget S, Parvaz P, Revol A. Thiram-induced cytotoxicity is accompanied by a rapid and drastic oxidation of reduced glutathione with consecutive lipid peroxidation and cell death. Toxicology 2001;163:153-62.10.1016/S0300-483X(01)00401-2Search in Google Scholar

McCarthy S, Somayajulu M, Sikorska M, Borowy-Borowski H, Pandey S. Paraquat induces oxidative stress and neuronal cell death; neuroprotection by water soluble Coenzyme Q-10. Toxicol Appl Pharmacol 2004;201:21-31.10.1016/j.taap.2004.04.019Search in Google Scholar

Bradford MM. A rapid and sensitive method for the quantification of microgram quantities of protein utilising the principle of protein-dye binding. Anal Biochem 1976;72:248-54.10.1016/0003-2697(76)90527-3Search in Google Scholar

Singh NP, McCoy MT, Tice RR, Schneider EL. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 1988;175:184-91.10.1016/0014-4827(88)90265-0Search in Google Scholar

Rusak G, Piantanida I, Mašić L, Kapuralin K, Durgo K, Kopjar N. Spectrophotometric analysis of flavonoid-DNA interactions and DNA damaging/protecting and cytotoxic potential of flavonoids in human peripheral blood lymphocytes. Chem-Biolo Interact 2010;188:181-9.10.1016/j.cbi.2010.07.008Search in Google Scholar

Guo Q, Zhao B, Shen S, Hou J, Hu J, Xin W. ESR study on the structure-antioxidant activity relationship of tea catechins and their epimers. BBA - General Subjects 1999;1427:13-23.10.1016/S0304-4165(98)00168-8Search in Google Scholar

Babich H, Krupka ME, Nissim HA, Zuckerbraun HL. Differential in vitro cytotoxicity of (-)-epicatechin gallate (ECG) to cancer cells from the human oral cavity. Toxicol in Vitro 2005;19:231-42.10.1016/j.tiv.2004.09.00115649637Search in Google Scholar

Khan N, Mukhtar H. Tea polyphenols for health promotion. Life Sci 2007;81:519-33.10.1016/j.lfs.2007.06.011322061717655876Search in Google Scholar

Yamamoto T, Hsu S, Lewis J, Wataha J, Dickinson D, Singh B, Bollag WB, Lockwood P, Ueta E, Osaki T, Schuster G. Green tea polyphenol causes differential oxidative environments in tumor versus normal epithelial cells. J Pharmacol Exp Therap 2003;307:230-6.10.1124/jpet.103.05467612954803Search in Google Scholar

Yang GY, Liao J, Kim K, Yurkow EJ, Yang CS. Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols. Carcinogenesis 1998;4:611-6.10.1093/carcin/19.4.6119600345Search in Google Scholar

Naasani I, Seimiya H, Tsuruo T. Telomerase inhibition, telomere shortening, and senescence of cancer cells by tea catechins. Biochem Biophys Res Commun 1998;240:391-6.10.1006/bbrc.1998.90759712707Search in Google Scholar

Morrow J. Looking for lipid peroxidation in vitro and in vivo: is seeing believing? [displayed on 19 May 2011]. Available at http://www.sfrbm.org/frs/Morrow2002.pdfSearch in Google Scholar

Elbling L, Weiss RM, Teufelhofer O, Uhl M, Knasmueller S, Schulte-Herman R, Berger W, Micksche M. Green tea extract and (-)-epigallocatechin-3-gallate, the major tea catechin, exert oxidant but lack antioxidant activities. FASEB J 2005;19:807-9.10.1096/fj.04-2915fje15738004Search in Google Scholar

Forman HJ, Fukuto JM, Torres M. Redox signalling: thiol chemistry defines which reactive oxygen and nitrogen species can act as second messengers. Am J Phisiol Cell Physiol 2004;287:C246-56.10.1152/ajpcell.00516.200315238356Search in Google Scholar

Kimura M, Umegaki K, Kasuya K, Sugisawa A, Higuchi M. The relation between single/double or repeated tea catehin ingestions and plasma antioxidant activity in humans. Eur J Clin Nutr 2002;56:1186-93.10.1038/sj.ejcn.160147112494303Search in Google Scholar

Kanadzu M, Lu Y, Morimoto K. Dual function of (-)-epigallocatechin gallate (EGCG) in healthy human lymphocytes. Cancer Lett 2006;241:250-5.10.1016/j.canlet.2005.10.02116303244Search in Google Scholar