Biomonitoring of Human Exposure to Triazine Herbicides

LeBaron HM, McFarland JE, Burnside OC, urednici. The Triazine Herbicides. Amsterdam: Elsevier; 2008.Search in Google Scholar

Berg M, Müller SR, Schwarzenbach RP. Simultaneous determination of triazines including atrazine and their major metabolites hydroxyatrazine, desethylatrazine and deisopropylatrazine in natural waters. Anal Chem 1995;67:1860-5.10.1021/ac00107a016Search in Google Scholar

Willson MP, Savage EP, Adrian DD, Aaronson MJ, Keefe TJ, Hamar DH, Tessari JT. Groundwater transport of the herbicide, atrazine, Weld County, Colorado. Bull Environ Contam Toxicol 1987;39:807-14.10.1007/BF01855859Search in Google Scholar

Dörfler U, Scheunert I. s-Triazine herbicides in rainwater with special reference to the situation in Germany. Chemosphere 1997;35:77-85.10.1016/S0045-6535(97)00140-9Search in Google Scholar

Ferrer I, Barcelö D, Thurman EM. Double-disk solid-phase extraction: simultaneous cleanup and trace enrichment of herbicides and metabolites from environmental samples. Anal Chem 1999;71:1009-15.10.1021/ac980975qSearch in Google Scholar

Loos R, Locoro G, Comero S, Contini S, Schwesig D, Werres F, Balsaa P, Gans O, Weiss S, Blaha L, Bolchi M, Gawlik BM. Pan-European survey on the occurrence of selected polar organic persistent pollutants in ground water. Water Res 2010;44:4115-26.10.1016/j.watres.2010.05.032Search in Google Scholar

Shiu WY, Ma KC, MaCkay D, Seiber JN, Wauchope RD. Solubilities of pesticides chemicals in water. Part II: Data compilation. Rev Environ Contam Toxicol 1990;16:15-187.10.1007/978-1-4612-3434-0_2Search in Google Scholar

Tomlin C, urednik. The Pesticide Manual. Incorporating the Agrochemicals Handbook. 10. izd. London: British Corp Protection Council; 1994.Search in Google Scholar

Noble A. Partition coefficients (n-octanol-water) for pesticides. J Chromatogr 1993;642:3-14.10.1016/0021-9673(93)80072-GSearch in Google Scholar

Fröbe Z, Štengl B, Lovrec I, Drevenkar V. n-Octanol/water partition coefficients and sorption behaviour of triazine herbicides and some of their degradation products. U: Proceedings of the COST 66 Workshop "Pesticides in soil and the environment"; Stradtford-upon-Avon, V. Britanija 1996. Sažeci str. 49-50.Search in Google Scholar

Prosen H, Zupančič-Kralj L. The interaction of triazine herbicides with humic acids. Chromatographia 2000;51: S155-64.10.1007/BF02492799Search in Google Scholar

Weber JB. Mechanisms of adsorption of s-triazines by clay colloids and factors affecting plant availability. U: Gunther FA, Gunther JD, urednici. Residue reviews: the triazine herbicides. Vol 32. New York: Springer-Verlag; 1970. str. 93-130.10.1007/978-1-4615-8464-3_5Search in Google Scholar

Büchel KH. Chemistry of Pesticides. New York (NY): John Wiley & Sons, Inc.; 1983.Search in Google Scholar

Sabik H, Jeannot R, Rondeau B. Multiresidue methods using solid-phase extraction techniques for monitoring priority pesticides, including triazines and degradation products, in ground and surface waters. J Chromatogr A 2000;885:217-36.10.1016/S0021-9673(99)01084-5Search in Google Scholar

Stevens JT, Breckenridge CB, Wetzel LT, Gillis JH, Leumpert LG, Eldridge JC. Hypothesis for mammary tumorigenesis in Sprague-Dawley rats exposed to certain triazine herbicides. J Toxicol Environ Health 1994;43:139-53.10.1080/15287399409531911Search in Google Scholar

Gojmerac T, Kniewald J. Atrazine biodegradation in rats - a model for mammalian metabolism. Bull Environ Contam Toxicol 1989;43:199-206.10.1007/BF01701748Search in Google Scholar

Kniewald J, Gojmerac T, Šimić B, Kniewald Z. The biodegradation of atrazine and the impact on reproductive system in mammals and avians-comparative study. U: Løkke H, Tyle H, Bro-Rasmussen F, urednici. 1^st European Conference on Ecotoxicology: a SECOTOX Regional Conference on testing, Prediction and Validation Pathways, Fate and Effects of Chemicals in Environment; 17-19 October 1988. Copenhagen, Danska. Lyngby: The Technical University of Denmark; 1988. str. 93-102.Search in Google Scholar

Babić-Gojmerac T, Kniewald Z, Kniewald J. Testosterone metabolism in neuroendocrine organs in male rats under atrazine and deethylatrazine influence. J Steroid Biochem 1989;33:141-6.10.1016/0022-4731(89)90369-5Search in Google Scholar

Kniewald J, Peruzović M, Gojmerac T, Milković K, Kniewald Z. Indirect influence of s-triazines on rat gonadotropic mechanism at early postnatal period. J Steroid Biochem 1987;27:1095-100.10.1016/0022-4731(87)90195-6Search in Google Scholar

Kniewald J, Jankominić M, Tomljenović A, Šimić B, Romac P, Vranešić Đ, Kniewald Z. Disorders of male rat reproductive tract under the influence of atrazine. J Appl Toxicol 2000;20:61-8.10.1002/(SICI)1099-1263(200001/02)20:1<61::AID-JAT628>3.0.CO;2-3Search in Google Scholar

Wetzel LT, Leumpert LG, Breckenridge CB, Tisdel MO, Stevens JT, Thakur AK, Extrom PJ, Eldridge JC. Chronic effects of atrazine on estrus and mammary tumor formation in female Sprague-Dawley and Fischer 344 rats. J Toxicol Environ Health 1994;43:169-82.10.1080/15287399409531913Search in Google Scholar

Stoker TE, Robinette CL, Cooper R. Maternal exposure to atrazine during lactation suppresses suckling-induced prolactin release and results in prostatitis in the adult offspring. Toxicol Sci 1999;52:68-79.10.1093/toxsci/52.1.68Search in Google Scholar

Cooper RL, Stoker TE, Tyrey L, Goldman JM, McElroy WK. Atrazine disrupts the hypothalamic control of pituitaryovarian function. Toxicol Sci 2000;53:297-307.10.1093/toxsci/53.2.297Search in Google Scholar

Pruett SB, Fan R, Zheng Q, Myers LP, Hebert P. Modeling and predicting immunological effects of chemical stressors: characterization of quantitative biomarker for immunological changes caused by atrazine and ethanol. Toxicol Sci 2003;75:343-54.10.1093/toxsci/kfg200Search in Google Scholar

Filipov NM, Pinchuk LM, Boyd BL, Crittenden PL. Immunotoxic effects of short-term atrazine exposure in young male C57BL/6 mice. Toxicol Sci 2005;86:324-32.10.1093/toxsci/kfi188Search in Google Scholar

Moore A, Waring CP. Mechanistic effects of a triazine pesticide on reproductive endocrine function in mature male Atlantic salmon (Salmo salar L.) parr. Pestic Biochem Physiol 1998;62:41-50.10.1006/pest.1998.2366Search in Google Scholar

Taets C, Aref S, Rayburn AL. The clastogenic potential of triazine herbicide combinations found in potable water supplies. Environ Health Perspect 1998;106:197-201.10.1289/ehp.98106197Search in Google Scholar

Butler MA, Hoagland RE. Genotoxicity assessment of atrazine and some major metabolites in the Ames test. Bull Environ Contam Toxicol 1989;43:797-804.10.1007/BF01702047Search in Google Scholar

Dunkelberg H, Fuchs J, Hengstler JG, Klein E, Oesch F, Strüder K. Genotoxic effects of the herbicides alachlor, atrazine, pendimethaline and simazine in mammalian cells. Bull Environ Contam Toxicol 1994;52:498-504.10.1007/BF00194135Search in Google Scholar

Želježić D, Garaj-Vrhovac V. Sister chromatid exchange and proliferative rate index in the longitudinal risk assessment of occupational exposure to pesticides. Chemosphere 2002;46:295-303.10.1016/S0045-6535(01)00073-XSearch in Google Scholar

Želježić D, Garaj-Vrhovac V. Chromosomal aberration and single-cell electrophoresis (comet) assay in the longitudinal risk assessment of occupational exposure to pesticides. Mutagenesis 2001;16:359-63.10.1093/mutage/16.4.359Search in Google Scholar

Sathiakumar N, Maclennan PA, Mandel J, Delzell E. A review of epidemiologic studies of triazines herbicides and cancer. Crit Rev Toxicol 2011;41(Suppl 1):1-34.10.3109/10408444.2011.554793Search in Google Scholar

Meli G, Bagnati R, Fanelli R, Benfenati E, Airoldi L. Metabolic profile of atrazine and N-nitrosoatrazine in rat urine. Bull Environ Contam Toxicol 1992;48:701-8.10.1007/BF00195990Search in Google Scholar

Lang D, Criegee D, Grothusen A, Saalfrank RW, Böcker RH. In vitro metabolism of atrazine, terbuthylazine, ametryne, and terbutryne in rats, pigs, and humans. Drug Metab Dispos 1996;24:859-65.Search in Google Scholar

Ikonen R, Kangas J, Savolainen H. Urinary atrazine metabolites as indicators for rat and human exposure to atrazine. Toxicol Lett 1988;44:109-12.10.1016/0378-4274(88)90136-1Search in Google Scholar

Bradway DE, Moseman RF. Determination of urinary residue levels of the N-dealkyl metabolites of triazine herbicides. J Agric Food Chem 1982;30:244-7.10.1021/jf00110a007Search in Google Scholar

Timchalk C, Dryzga MD, Langvardt PW, Kastl PE, Osborne DW. Determination of the effect of tridiphane on the pharmacokinetics of [¹⁴C]-atrazine following oral administration to male fisher 344 rats. Toxicology 1990;61:27-40.10.1016/0300-483X(90)90004-ZSearch in Google Scholar

Rodríguez J, Harkin JM. New intermediates of dealkylation of [¹⁴C]-atrazine by mouse liver microsomes. Pestic Biochem Physiol 1995;53:23-33.10.1006/pest.1995.1051Search in Google Scholar

Hanioka N, Jinno H, Kitazawa K, Tanaka-Kagawa T, Nishimura T, Ando M, Ogawa K. In vitro biotransformation of atrazine by rat liver microsomal cytochrome P450 enzymes. Chem Biol Interact 1998;116:181-98.10.1016/S0009-2797(98)00086-6Search in Google Scholar

Erickson MD, Frank CW, Morgan DP. Determination of striazine herbicide residues in urine studies of excretion and metabolism in swine as a model to human metabolism. J Agric Food Chem 1979;27:743-5.10.1021/jf60224a006Search in Google Scholar

Ross MK, Filipov NM. Determination of atrazine and its metabolites in mouse urine and plasma by LC-MS analysis. Anal Biochem 2006;351:161-73.10.1016/j.ab.2006.01.050Search in Google Scholar

Catenacci G, Maroni M, Cottica D, Pozzoli L. Assessment of human exposure to atrazine through the determination of free atrazine in urine. Bull Environ Contam Toxicol 1990;44:1-7.10.1007/BF01702354Search in Google Scholar

Catenacci G, Barbieri F, Bersani M, Ferioli A, Cottica D, Maroni M. Biological monitoring of human exposure to atrazine. Toxicol Lett 1993;69:217-22.10.1016/0378-4274(93)90107-9Search in Google Scholar

Panuwet P, Restrepo PA, Magsumbol M, Jung YK, Montesano MA, Needham LL, Barr BD. An improved high-performance liquid chromatography-tandem mass spectrometric method to measure atrazine and its metabolites in human urine. J Chromatogr B 2010;878:957-62.10.1016/j.jchromb.2010.02.02520299293Search in Google Scholar

Koivunen ME, Dettmer K, Vermeulen R, Bakke B, Gee SJ, Hammock BD. Improved methods for urinary atrazine mercapturate analysis-Assessment of enzyme-linked immunosorbent assay (ELISA) and a novel liquid chromatography-mass spectrometry (LC-MS) method utilizing online solid phase extraction (SPE). Anal Chim Acta 2006;572:180-9.10.1016/j.aca.2006.05.03717723476Search in Google Scholar

Panuwet P, Nguyen JV, Kuklenyik P, Udunka S, Needham LL, Barr BD. Quantification of atrazine and its metabolites in urine by on-line solid-phase extraction-high-performance liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem 2008;391:1931-9.10.1007/s00216-008-2102-018454284Search in Google Scholar

Kumazawa T, Lee X-P, Kondo K, Sato K, Seno H, Watanabe-Suzuki K, Ishii A, Suzuki O. Determination of triazine herbicides in human body fluids by solid-phase microextraction and capillary gas chromatography. Chromatographia 2000;52:195-9.10.1007/BF02490456Search in Google Scholar

Beltran J, López FJ, Hernández F. Solid-phase microextraction in pesticide residue analysis. J Chromatogr A 2000;885:389-404.10.1016/S0021-9673(00)00142-4Search in Google Scholar

Mendaš G, Tkalčević B, Drevenkar V. Determination of chloro- and methylthiotriazine compounds in human urine: extraction with diethyl ether and C₁₈ solid-phase extraction for gas chromatigraphic analysis with nitrogen-selective and electron capture detection. Anal Chim Acta 2000;424:7-18.10.1016/S0003-2670(00)01150-8Search in Google Scholar

Lucas AD, Jones AD, Goodrow MH, Saiz SG, Blewett C, Seiber JN, Hammock BD. Determination of atrazine metabolites in human urine development of a biomarker of exposure. Chem Res Toxicol 1993;6:107-16.10.1021/tx00031a017Search in Google Scholar

Perry MJ, Christiani DC, Degenhardt D, Tortorelli J, Strauss J, Sonzogni WC. Urinalysis of atrazine exposure in farm pesticide applicators. Toxicol Ind Health 2000;16:285-90.10.1177/074823370001600705Search in Google Scholar

Hines CJ, Deddens JA, Striley CAF, Biagini RE, Shoemaker DA, Brown KK, Mackenzie BA, Delon Hull R. Biological monitoring for selected herbicide biomarkers in the urine of exposed custom applicators: Application of mixed-effect models. Ann Occup Hyg 2003;47:503-17.Search in Google Scholar

Bucholz BA, Fultz E, Haack KW, Vogel JS, Gilman SD, Gee SJ, Hammock BD, Hui X, Wester RC, Maibach HI. HPLCaccelerator MS measurement of atrazine metabolites in human urine after dermal exposure. Anal Chem 1999;71:3519-25.10.1021/ac990152gSearch in Google Scholar

Baker SE, Barr DB, Driskell WJ, Beson MD, Needham LL. Quantification of selected pesticide metabolites in human urine using isotope dilution high-performance liquid chromatography / tandem mass spectrometry. J Expo Anal Environ Epidemiol 2000;10:789-98.10.1038/sj.jea.7500123Search in Google Scholar

Pozzebon JM, Querioz SCN, Melo LFC, Kapor MA, Jardim ICSF. Application of new high-performance liquid chromatography and solid phase extraction materials to the analysis of pesticides in human urine. J Chromatogr A 2003;987:381-7.10.1016/S0021-9673(02)01434-6Search in Google Scholar

Olsson AO, Baker SE, Nguyen JV, Romanoff LC, Unduka SO, Walker RD, Flemmen KL, Barr DB. A liquid chromatography-tandem mass spectrometry multiresidue method for quantification of specific metabolites of organophosphorus pesticides, synthetic pyrethroids, selected herbicides, and DEET in human urine. Anal Chem 2004;76:2453-61.10.1021/ac035540415117183Search in Google Scholar

Curwin BD, Hein MJ, Sanderson WT, Barr DB, Heederik D, Reynolds SJ, Ward EM, Alavanja MC. Urinary and hand wipe pesticides levels among farmers and nonfarmers in Iowa. J Expo Anal Environ Epidemiol 2005;15:500-8.10.1038/sj.jea.750042815841098Search in Google Scholar

Beeson MD, Driskell WJ, Barr DB. Isotope dilution highperformance liquid chromatography/tandem mass spectrometry method for quantifying urinary metabolites of atrazine, malathion and 2,4-dichlorophenoxyacetic acid. Anal Chem 1999;71:3526-30.10.1021/ac990130uSearch in Google Scholar

Barr BD, Panuwet P, Nguyen JV, Udunka S, Needham LL. Assessing exposure to atrazine and its metabolites using biomonitoring. Environ Health Perspect 2007;115:1474-8.10.1289/ehp.10141Search in Google Scholar

Gilman SD, Gee SJ, Hammock BD, Vogel JS, Haack K, Buchholz BA, Freeman SPHT, Wester RC, Hui X, Maibach HI. Analytical performance of accelerator mass spectrometry and liquid scintillation counting for detection of ¹⁴C-labeled atrazine metabolites in human urine. Anal Chem 1998;70:3463-9.10.1021/ac971383vSearch in Google Scholar

Jaeger LL, Jones AD, Hammock BD. Development of an enzyme-linked immunosorbent assay for atrazine mercapturic acid in human urine. Chem Res Toxicol 1998;11:342-52.10.1021/tx9701844Search in Google Scholar

De Rooij BM, Commandeur JNM, Vermeulen NPE. Mercapturic acid as biomarkers of exposure to electrophilic chemicals: application to environmental and industrial chemicals. Biomarkers 1998;3:239-303.10.1080/135475098231101Search in Google Scholar

Perbellini L, Veronese N, Princivalle A. Mercapturic acids in the biological monitoring of occupational exposure to chemicals. J Chromatogr B 2002;781:269-90.10.1016/S1570-0232(02)00501-9Search in Google Scholar