<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Maternal antibody-mediated fetal red blood cell destruction secondary to non-D Rh system antibodies is a significant cause of hemolytic disease of the fetus and newborn. Here, we report a rare case of severe perinatal hemolytic disease associated with maternal antibody to the e antigen. In addition to severe anemia, the infant developed hyperbilirubinemia. Resolution of the infant’s anemia and hyperbilirubinemia occurred after treatment with phototherapy, intravenous immunoglobulin, and transfusion.</p>
</abstract>

Maternal antibody-mediated fetal red blood cell destruction secondary to non-D Rh system antibodies is a significant cause of hemolytic disease of the fetus and newborn. Here, we report a rare case of severe perinatal hemolytic disease associated with maternal antibody to the e antigen. In addition to severe anemia, the infant developed hyperbilirubinemia. Resolution of the infant’s anemia and hyperbilirubinemia occurred after treatment with phototherapy, intravenous immunoglobulin, and transfusion.

Severe perinatal hemolytic disease due to anti-e

Immunohematology

{"article-title":"Severe perinatal hemolytic disease due to anti-e"}

Maternal antibody-mediated fetal red blood cell destruction secondary to non-D Rh system antibodies is a significant cause of hemolytic disease of the fetus...

Severe perinatal hemolytic disease due to anti-e

Article Category: case-report

Pubblicato online: 25 giu 2021

Pagine: 72 - 77

DOI: https://doi.org/10.21307/immunohematology-2021-011

© 2021 G. Soler-Noda et al., published by Sciendo