<abstract xmlns="http://www.w3.org/1999/xhtml">The red cells of a white male blood donor typed as Rh:–1, –2, –3,w4,w5,6,–17,w19,–31,–32,–34, and –46. Although the donor has no history of transfusion, his serum contains an alloantibody that is weakly reactive with most red blood cells (RBCs) tested. Only Rhnull and D–– RBCs are nonreactive. Reactivity is enhanced with ficin- or papain-treated RBCs and is unaffected by AET or DTT treatment of the RBCs. Previously described Rh:–46 RBCs have been of deletion types D––, D••, and Rhnull or Rh:32. In three multitransfused patients, the Rh46 antigen was temporarily suppressed and the phenotype eventually reverted to normal. This is the first report of RBCs of the Rh:–32,–46 phenotype that are not of a rare Rh deletion or Rhnull type. In addition, the Rh:w5,w19,–31,–34 phenotype is rarely found in whites. <bold><italic>Immunohematology</italic></bold> 1994; 10:130–133.</abstract>

The red cells of a white male blood donor typed as Rh:–1, –2, –3,w4,w5,6,–17,w19,–31,–32,–34, and –46. Although the donor has no history of transfusion, his serum contains an alloantibody that is weakly reactive with most red blood cells (RBCs) tested. Only Rhnull and D–– RBCs are nonreactive. Reactivity is enhanced with ficin- or papain-treated RBCs and is unaffected by AET or DTT treatment of the RBCs. Previously described Rh:–46 RBCs have been of deletion types D––, D••, and Rhnull or Rh:32. In three multitransfused patients, the Rh46 antigen was temporarily suppressed and the phenotype eventually reverted to normal. This is the first report of RBCs of the Rh:–32,–46 phenotype that are not of a rare Rh deletion or Rhnull type. In addition, the Rh:w5,w19,–31,–34 phenotype is rarely found in whites. Immunohematology 1994; 10:130–133.

First example of Rh:–32,–46 red cell phenotype

National Reference Laboratory for Blood Group Serology

Immunohematology

{"article-title":"First example of Rh:\u201332,\u201346 red cell phenotype"}

The red cells of a white male blood donor typed as Rh:–1, –2, –3,w4,w5,6,–17,w19,–31,–32,–34, and –46. Although the donor has no history of transfusion, his...

First example of Rh:–32,–46 red cell phenotype

Pubblicato online: 30 nov 2020

Pagine: 130 - 133

DOI: https://doi.org/10.21307/immunohematology-2019-939

© 1994 J.R. Storry et al., published by Sciendo