<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Transfusion-related acute lung injury (TRALI) is a rare complication of transfusion, for which the true incidence remains obscure, since there are a number of factors that may lead to misdiagnosis. Despite this, it continues to be the leading cause of transfusion-associated mortality. Here we present a historical case of TRALI in an elderly female who received group AB plasma and discuss how current mitigation strategies would likely have prevented its occurrence. It is important to remember that both immune and non-immune factors play a role in TRALI pathogenesis, and although current preventative strategies may decrease TRALI’s incidence, they likely will not eliminate it. <italic><bold>Immunohematology</bold></italic><bold>2015;31:155–158.</bold></p></abstract>

Transfusion-related acute lung injury (TRALI) is a rare complication of transfusion, for which the true incidence remains obscure, since there are a number of factors that may lead to misdiagnosis. Despite this, it continues to be the leading cause of transfusion-associated mortality. Here we present a historical case of TRALI in an elderly female who received group AB plasma and discuss how current mitigation strategies would likely have prevented its occurrence. It is important to remember that both immune and non-immune factors play a role in TRALI pathogenesis, and although current preventative strategies may decrease TRALI’s incidence, they likely will not eliminate it. Immunohematology2015;31:155–158.

Transfusion-related acute lung injury in an era of TRALI risk mitigation

Immunohematology

{"article-title":"Transfusion-related acute lung injury in an era of TRALI risk mitigation"}

Transfusion-related acute lung injury (TRALI) is a rare complication of transfusion, for which the true incidence remains obscure, since there are a number of...

Transfusion-related acute lung injury in an era of TRALI risk mitigation

Article Category: Case Report

Pubblicato online: 26 ott 2019

Pagine: 155 - 158

DOI: https://doi.org/10.21307/immunohematology-2019-085

Parole chiave
TRALI, AB plasma

© 2015 J.C. Lavelle et al., published by Sciendo

Transfusion-related acute lung injury in an era of TRALI risk mitigation

Article Category: Case Report

Pubblicato online: 26 ott 2019

Pagine: 155 - 158

DOI: https://doi.org/10.21307/immunohematology-2019-085

Parole chiaveTRALI, AB plasma

© 2015 J.C. Lavelle et al., published by Sciendo

Parole chiave
TRALI, AB plasma