<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Automated testing platforms facilitate the introduction of red cell genotyping of patients and blood donors. Fluidic microarray systems, such as Luminex XMAP (Austin, TX), are used in many clinical applications, including HLA and HPA typing. The Progenika ID CORE XT (Progenika Biopharma-Grifols, Bizkaia, Spain) uses this platform to analyze 29 polymorphisms determining 37 antigens in 10 blood group systems. Once DNA has been extracted, processing time is approximately 4 hours. The system is highly automated and includes integrated analysis software that produces a file and a report with genotype and predicted phenotype results. <italic><bold>Immunohematology</bold></italic><bold>2015;31:62–68.</bold></p></abstract>

Automated testing platforms facilitate the introduction of red cell genotyping of patients and blood donors. Fluidic microarray systems, such as Luminex XMAP (Austin, TX), are used in many clinical applications, including HLA and HPA typing. The Progenika ID CORE XT (Progenika Biopharma-Grifols, Bizkaia, Spain) uses this platform to analyze 29 polymorphisms determining 37 antigens in 10 blood group systems. Once DNA has been extracted, processing time is approximately 4 hours. The system is highly automated and includes integrated analysis software that produces a file and a report with genotype and predicted phenotype results. Immunohematology2015;31:62–68.

An overview of the Progenika ID CORE XT: an automated genotyping platform based on a fluidic microarray system

Immunohematology

Automated testing platforms facilitate the introduction of red cell genotyping of patients and blood donors. Fluidic microarray systems, such as Luminex XMAP...

An overview of the Progenika ID CORE XT: an automated genotyping platform based on a fluidic microarray system

Article Category: Molecular Method

Pubblicato online: 26 ott 2019

Pagine: 62 - 68

DOI: https://doi.org/10.21307/immunohematology-2019-072

Parole chiave
blood group, DNA-based typing methodology, genotyping

© 2015 M. Goldman et al., published by Sciendo

An overview of the Progenika ID CORE XT: an automated genotyping platform based on a fluidic microarray system

Article Category: Molecular Method

Pubblicato online: 26 ott 2019

Pagine: 62 - 68

DOI: https://doi.org/10.21307/immunohematology-2019-072

Parole chiaveblood group, DNA-based typing methodology, genotyping

© 2015 M. Goldman et al., published by Sciendo

Parole chiave
blood group, DNA-based typing methodology, genotyping