Prevention of life-threatening bleeding complication from splenic venous ectasia by B-mode-, color Doppler- and contrast-enhanced ultrasound in a patient with ALL
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Fig. 1.
B-US shows splenomegaly with inhomogeneous parenchyma and multiple cyst-like lesions (A, B). In color Doppler sonography (CDS), these lesions present low-impedance continuous venous flow signal (C, D). Contrast-enhanced sonography (CEUS) after one (E) and 6 minutes (F) revealed the echo-free lesions suspected for venous ectasias
Fig. 2.
Contrast-enhanced computed tomography (CT) presents a splenomegaly with inhomogeneous contrast uptake (arrow) (courtesy of Prof. Dr. Mahnken, Department of Radiology, Marburg)
Fig. 3.
During short-term follow-up, B-US, CDS and CEUS showed size progression of the “cyst-like” vascular lesions
Fig. 4.
Organ preparation after emergency splenectomy shows macroscopically organ rupture (A). Overview of the rupture site (top) with parenchymal bleeding (bottom right) (B). In HE 1:20, splenic rupture with capsule and parenchymal defect were seen. The overview shows no typical architecture of the spleen with red and white pulp. C. In HE (magnification ×200), diffuse infiltration of the red pulp/spleen parenchyma by ALL-blasts with enlarged vesicular nucleoli and only a small cytoplasm was observed (courtesy of Dr. A. Ramaswamy, Department of Pathology, Marburg)