<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec>
<h3>Aim</h3>
<p>To investigate the diagnostic value of resistance index (RI) in differentiating focal liver lesions.</p>
</sec>
<sec>
<h3>Patients and methods</h3>
<p>In this retrospective study, a total of 576 patients with histologically confirmed focal liver lesions were included. Each patient underwent B-mode ultrasound examination and color Doppler ultrasound examination. The RI values of different focal liver lesions were recorded and compared.</p>
</sec>
<sec>
<h3>Results</h3>
<p>The mean RI value of benign lesions was significantly lower than that of malignant lesions (0.54 ± 0.10 <italic>vs</italic>. 0.71 ± 0.12) (<italic>p</italic> &lt;0.05). In malignant lesions, the RI value of intrahepatic cholangiocarcinoma was significantly lower than that of hepatocellular carcinoma lesions. Furthermore, in hepatocellular carcinoma lesions, the RI of large lesions (group 4: >10 cm) was significantly lower than that of small lesions (group 1: ≤2 cm, group 2: 2–5 cm) (<italic>p</italic> &lt;0.05). Taken RI of 0.615 as a cutoff value to differentiate malignant and benign lesions, the sensitivity, specificity, positive predictive value and negative predictive value were 82.80%, 81.00%, 81.34% and 82.48%, respectively.</p>
</sec>
<sec>
<h3>Conclusion</h3>
<p>Color Doppler ultrasound examination is a valuable imaging method in detecting blood flow signal within liver lesions. The RI parameter should be helpful in differentiating malignant and benign liver tumors.</p>
</sec>
</abstract>

Aim
To investigate the diagnostic value of resistance index (RI) in differentiating focal liver lesions.


Patients and methods
In this retrospective study, a total of 576 patients with histologically confirmed focal liver lesions were included. Each patient underwent B-mode ultrasound examination and color Doppler ultrasound examination. The RI values of different focal liver lesions were recorded and compared.


Results
The mean RI value of benign lesions was significantly lower than that of malignant lesions (0.54 ± 0.10 vs. 0.71 ± 0.12) (p <0.05). In malignant lesions, the RI value of intrahepatic cholangiocarcinoma was significantly lower than that of hepatocellular carcinoma lesions. Furthermore, in hepatocellular carcinoma lesions, the RI of large lesions (group 4: >10 cm) was significantly lower than that of small lesions (group 1: ≤2 cm, group 2: 2–5 cm) (p <0.05). Taken RI of 0.615 as a cutoff value to differentiate malignant and benign lesions, the sensitivity, specificity, positive predictive value and negative predictive value were 82.80%, 81.00%, 81.34% and 82.48%, respectively.


Conclusion
Color Doppler ultrasound examination is a valuable imaging method in detecting blood flow signal within liver lesions. The RI parameter should be helpful in differentiating malignant and benign liver tumors.

The diagnostic value of Doppler Resistive Index in the differential diagnosis of focal liver lesions

Journal of Ultrasonography

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Aim
To investigate the diagnostic value of resistance index (RI) in differentiating focal liver lesions.


Patients and methods
In this retrospective study, a total of 576 patients with histologically confirmed focal liver lesions were included. Each patient underwent B-mode ultrasound examination and color Doppler ultrasound examination. The RI values of different focal liver lesions were recorded and compared.


Results
The mean RI value of benign lesions was significantly lower than that of malignant lesions (0.54 ± 0.10 vs. 0.71 ± 0.12) (p 10 cm) was significantly lower than that of small lesions (group 1: ≤2 cm, group 2: 2–5 cm) (p <0.05). Taken RI of 0.615 as a cutoff value to differentiate malignant and benign lesions, the sensitivity, specificity, positive predictive value and negative predictive value were 82.80%, 81.00%, 81.34% and 82.48%, respectively.


Conclusion
Color Doppler ultrasound examination is a valuable imaging method in detecting blood flow signal within liver lesions. The RI parameter should be helpful in differentiating malignant and benign liver tumors.

Aim
To investigate the diagnostic value of resistance index (RI) in differentiating focal liver lesions.


Patients and methods
In this retrospective study, a...

The diagnostic value of Doppler Resistive Index in the differential diagnosis of focal liver lesions

Article Category: Research paper

Pubblicato online: 11 mag 2023

Pagine: e45 - e52

Ricevuto: 09 ott 2022

Accettato: 03 gen 2023

DOI: https://doi.org/10.15557/jou.2023.0010

Parole chiave
B-mode ultrasound (BMUS), focal liver lesion (FLL), resistance index (RI), hepatocellular carcinoma (HCC), focal nodular hyperplasia (FNH)

© 2023 Yi Dong et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

The diagnostic value of Doppler Resistive Index in the differential diagnosis of focal liver lesions

Article Category: Research paper

Pubblicato online: 11 mag 2023

Pagine: e45 - e52

Ricevuto: 09 ott 2022

Accettato: 03 gen 2023

DOI: https://doi.org/10.15557/jou.2023.0010

Parole chiaveB-mode ultrasound (BMUS), focal liver lesion (FLL), resistance index (RI), hepatocellular carcinoma (HCC), focal nodular hyperplasia (FNH)

© 2023 Yi Dong et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Parole chiave
B-mode ultrasound (BMUS), focal liver lesion (FLL), resistance index (RI), hepatocellular carcinoma (HCC), focal nodular hyperplasia (FNH)