<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec id="j_jou.2022.0035_s_001">
<h3>Aim</h3>
<p>To evaluate and measure the mean cross-sectional area of the tibial and median nerves in patients with diabetic peripheral neuropathy, and to study the association between high-resolution ultrasonographic findings in diabetic peripheral neuropathy with the duration of illness, glycosylated haemoglobin values, random blood sugar levels, and aesthesiometry (using monofilament examination).</p>
</sec>
<sec id="j_jou.2022.0035_s_002">
<h3>Material and methods</h3>
<p>A prospective observational study was conducted among 63 patients who were diagnosed with type 2 diabetes mellitus and underwent ultrasound and monofilament examinations. The cross-sectional area of the median nerve of the dominant hand and the tibial nerves was calculated on ultrasound examination.</p>
</sec>
<sec id="j_jou.2022.0035_s_003">
<h3>Results</h3>
<p>The mean cross-sectional area of the median and tibial nerves was higher in patients with poor glycaemic control, with the mean cross-sectional area of the median nerve being 10.9, 12.8, 13.0, and 12.9 mm<sup>2</sup> at various points in the leg in cases where the monofilament examination was negative, as compared to 7.30, 7.78, 7.91, 7.87 mm<sup>2</sup> in patients with positive monofilament examination results. There was a significant positive correlation between the cross-sectional area of the tibial and median nerves and HbA<sub>1c</sub>, duration of diabetes, aesthesiometry, and random blood sugar levels. With an increase in HbA<sub>1c</sub>, duration of diabetes, and random blood sugar levels, there was a corresponding increase in the cross-sectional area of the nerves. These findings helped us to identify diabetic peripheral neuropathy.</p>
</sec>
<sec id="j_jou.2022.0035_s_004">
<h3>Conclusions</h3>
<p>High-resolution ultrasonography along with aesthesiometry and HbA<sub>1c</sub> values can be an effective and easily available tool for detecting changes secondary to diabetic peripheral neuropathy. The method has a potential to replace or substitute nerve conduction tests in the near future.</p>
</sec>
</abstract>

Aim
To evaluate and measure the mean cross-sectional area of the tibial and median nerves in patients with diabetic peripheral neuropathy, and to study the association between high-resolution ultrasonographic findings in diabetic peripheral neuropathy with the duration of illness, glycosylated haemoglobin values, random blood sugar levels, and aesthesiometry (using monofilament examination).


Material and methods
A prospective observational study was conducted among 63 patients who were diagnosed with type 2 diabetes mellitus and underwent ultrasound and monofilament examinations. The cross-sectional area of the median nerve of the dominant hand and the tibial nerves was calculated on ultrasound examination.


Results
The mean cross-sectional area of the median and tibial nerves was higher in patients with poor glycaemic control, with the mean cross-sectional area of the median nerve being 10.9, 12.8, 13.0, and 12.9 mm2 at various points in the leg in cases where the monofilament examination was negative, as compared to 7.30, 7.78, 7.91, 7.87 mm2 in patients with positive monofilament examination results. There was a significant positive correlation between the cross-sectional area of the tibial and median nerves and HbA1c, duration of diabetes, aesthesiometry, and random blood sugar levels. With an increase in HbA1c, duration of diabetes, and random blood sugar levels, there was a corresponding increase in the cross-sectional area of the nerves. These findings helped us to identify diabetic peripheral neuropathy.


Conclusions
High-resolution ultrasonography along with aesthesiometry and HbA1c values can be an effective and easily available tool for detecting changes secondary to diabetic peripheral neuropathy. The method has a potential to replace or substitute nerve conduction tests in the near future.

Role of high-resolution ultrasonography in the evaluation of the tibial and median nerves in diabetic peripheral neuropathy

Journal of Ultrasonography

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Aim
To evaluate and measure the mean cross-sectional area of the tibial and median nerves in patients with diabetic peripheral neuropathy, and to study the...

Role of high-resolution ultrasonography in the evaluation of the tibial and median nerves in diabetic peripheral neuropathy

Article Category: research-paper

Pubblicato online: 01 ott 2022

Pagine: e209 - e215

Ricevuto: 19 mar 2022

Accettato: 14 giu 2022

DOI: https://doi.org/10.15557/jou.2022.0035

Parole chiave
diabetes, peripheral neuropathy, ultrasonography

© 2022 Tanu Ranjan et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Role of high-resolution ultrasonography in the evaluation of the tibial and median nerves in diabetic peripheral neuropathy

Article Category: research-paper

Pubblicato online: 01 ott 2022

Pagine: e209 - e215

Ricevuto: 19 mar 2022

Accettato: 14 giu 2022

DOI: https://doi.org/10.15557/jou.2022.0035

Parole chiavediabetes, peripheral neuropathy, ultrasonography

© 2022 Tanu Ranjan et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Parole chiave
diabetes, peripheral neuropathy, ultrasonography