[
1. Cash BD. Evidence-based medicine as it applies to acid suppression in the hospitalized patient. Crit Care Med. 2002; 30(6 ): S373-8.10.1097/00003246-200206001-0000812072665
]Search in Google Scholar
[
2. Thorsen K, Søreide JA, Kvaløy JT, Glomsaker T, Søreide K. Epidemiology of perforated peptic ulcer: age- and gender-adjusted analysis of incidence and mortality. World J Gastroenterol. 2013; 19(3): 347-54.10.3748/wjg.v19.i3.347355481823372356
]Search in Google Scholar
[
3. Abraham E. Acid suppression in a critical care environment: state of the art and beyond. Crit Care Med. 2002; 30(6 Suppl): S349-50.10.1097/00003246-200206001-0000112072659
]Search in Google Scholar
[
4. Cook DJ, Fuller HD, Guyatt GH, et al. Risk factors for gastrointestinal bleeding in critically ill patients: Canadian Critical Care Trials Groups. N Engl J Med 1994; 330:397-81.10.1056/NEJM1994021033006018284001
]Search in Google Scholar
[
5. Fennerty MB. Pathophysiology of the upper gastrointestinal tract in the critically ill patient: rationale for the therapeutic benefits of acid suppression. Crit Care Med. 2002; 30(6 Suppl): S351-5.10.1097/00003246-200206001-0000212072660
]Search in Google Scholar
[
6. Conrad SA. Acute upper gastrointestinal bleeding in critically ill patients: causes and treatment modalities. Crit Care Med. 2002; 30(6 Suppl): S365-8.10.1097/00003246-200206001-0000612072663
]Search in Google Scholar
[
7. Jaspersen D, Koerner T, Schorr W, et al: Helicobacter pylori eradication reduces the rate of rebleeding in ulcer hemorrhage. Gastrointest Endosc. 1995; 41:5–7.10.1016/S0016-5107(95)70267-97698624
]Search in Google Scholar
[
8. Halm U, Halm F, Thein D, et al: Helicobacter pylori infection: A risk factor for upper gastrointestinal bleeding after cardiac surgery? Crit Care Med. 2000; 28:110-13.10.1097/00003246-200001000-0001810667508
]Search in Google Scholar
[
9. Simoens M, Gevers AM, Rutgeerte P: Endoscopic therapy for upper gastrointestinal hemorrhage: A state of the art. Hepatogastroenterology. 1999; 46:737–45.
]Search in Google Scholar
[
10. Savides TJ, Jensen DM: Therapeutic endoscopy for nonvariceal gastrointestinal bleeding. Gastroenterol Clin North Am. 2000; 29:465-87.10.1016/S0889-8553(05)70123-010836190
]Search in Google Scholar
[
11. Berenholtz S: Management of upper gastrointestinal hemorrhage. Resident Reporter. 1999; 4:112-18.
]Search in Google Scholar
[
12. Rockall TA, Logan RF, Devlin HB, Northfield TC. Risk assessment after acute upper gastrointestinal haemorrhage. Gut. 1996;38(3):316-321.10.1136/gut.38.3.31613830578675081
]Search in Google Scholar
[
13. Richter-Schrag H-J, Glatz T, Walker C, Fischer A, Thimme R. First-line endoscopic treatment with overthe-scope clips significantly improves the primary failure and rebleeding rates in high-risk gastrointestinal bleeding: A single-center experience with 100 cases. Am J Gastroenterol. 2016;22(41):9162-9171.
]Search in Google Scholar
[
14. Mokhtare M, Bozorgi V, Agah S, et al. Comparison of Glasgow-Blatchford score and full Rockall score systems to predict clinical outcomes in patients with upper gastrointestinal bleeding. Clin Exp Gastroenterol. 2016; 9:337-343.10.2147/CEG.S114860509675527826205
]Search in Google Scholar
[
15. Barer D, Ogilvie A, Henry D, et al: Cimetidine and tranexamic acid in the treatment of acute upper gastrointestinal-tract bleeding. N Engl J Med 1983; 308:1571–1575.10.1056/NEJM1983063030826066343868
]Search in Google Scholar
[
16. Walt RP, Cottrell J, Mann SG, et al: Continuous intravenous famotidine for haemorrhage from peptic ulcer. Lancet 1992; 340:143-47.
]Search in Google Scholar
[
17. Schaffalitzky de Muckadell OB, Havelund T, Harling H, et al. Effect of omeprazole on the outcome of endoscopically treated bleeding peptic ulcers. Scand J Gastroenterol. 1997; 32:320-27.10.3109/003655297090076799140153
]Search in Google Scholar
[
18. Lau JY, Sung JJ, Lee KKC, et al. Effect of intravenous omeprazole on recurrent bleeding after endoscopic treatment of bleeding peptic ulcers. N Engl J Med. 2000; 343:10-16.10.1056/NEJM20000803343050110922420
]Search in Google Scholar
[
19. Ganser AL, Forte JG. K+-stimulated ATPase in purified microsomes of bullfrog oxyntic cells. Biochem Biophys Acta. 1973; 307: 169-80.10.1016/0005-2736(73)90035-74351147
]Search in Google Scholar
[
20. Parsons ME, Keeling DJ. Novel approaches to the pharmacological blockade of gastric acid secretion. Expert Opin Investig Drugs. 2005; 14:411-21.10.1517/13543784.14.4.41115882117
]Search in Google Scholar
[
21. Sachs G, Shin JM, Briving C, Wallmark B, Hersey S. The pharmacology of the gastric acid pump: The H+, K+- ATPase. Annu Rev Pharmacol Toxicol. 1995; 35:277–305.10.1146/annurev.pa.35.040195.0014257598495
]Search in Google Scholar
[
22. Robinson M. Proton pump inhibitors: update on their role in acid-related gastrointestinal diseases. Int J Clin Pract. 2005; 59:709-15.10.1111/j.1368-5031.2005.00517.x15924600
]Search in Google Scholar
[
23. Ang TL, Fock KM. Nocturnal acid breakthrough: clinical significance and management. J Gastroenterol Hepatol 2006; 21(Suppl 5): S125-28.10.1111/j.1440-1746.2006.04717.x
]Search in Google Scholar
[
24. Vakil N. Review article: new pharmacological agents for the treatment of gastro-oesophageal reflux disease. Aliment Pharmacol Ther 2004; 19:1041-49.10.1111/j.1365-2036.2004.01957.x15142193
]Search in Google Scholar
[
25. Faleck DM, Salmasian H, Furuya EY, Larson EL, Abrams JA, Freedberg DE. Proton pump inhibitors do not affect risk for Clostridium difficile infection in the intensive care unit. Am J Gastroenterol. 2016;111(11):1641-48.10.1038/ajg.2016.343509697027575714
]Search in Google Scholar
[
26. Barletta JF, Sclar DA. Proton pump inhibitors increase the risk for hospital-acquired Clostridium difficile infection in critically ill patients. Critical Care. 2014;18(6):714.10.1186/s13054-014-0714-7429382625540023
]Search in Google Scholar
[
27. Freedberg DE, Salmasian H, Friedman C, Abrams JA. Proton Pump Inhibitors and Risk for Recurrent Clostridium Difficile Infection Among Inpatients. Am J Gastroenterol. 2013;108(11):1794-801.10.1038/ajg.2013.333396606024060760
]Search in Google Scholar
[
28. Wurst W, Hartmann M. Current status of acid pump antagonists (reversible PPIs). Yale J Biol Med. 1996; 69:233–243.
]Search in Google Scholar
[
29. Andersson K, Carlsson E. Potassium-competitive acid blockade: a new therapeutic strategy in acid-related diseases. Pharmacol Ther. 2005; 108:294–307.10.1016/j.pharmthera.2005.05.00516000224
]Search in Google Scholar
[
30. Kahrilas PJ, Dent J, Lauritsen K, Malfertheiner P, Denison H, Franzén S, Hasselgren G. A randomized, comparative study of three doses of AZD0865 and esomeprazole for healing of reflux esophagitis. Clin Gastroenterol Hepatol 2007; 5:1385-391.10.1016/j.cgh.2007.08.01417950677
]Search in Google Scholar
[
31. Bezabeh S, Mackey AC, Kluetz P, Jappar D, Korvick J. Accumulating evidence for a drug-drug interaction between methotrexate and proton pump inhibitors. Oncologist. 2012;17(4):550-4.10.1634/theoncologist.2011-0431333683722477728
]Search in Google Scholar
[
32. Harty RF, Ancha HB. Stress ulcer bleeding. Curr Treat Options Gastroenterol. 2006; 9: 157-66.10.1007/s11938-006-0034-316539876
]Search in Google Scholar
[
33. Spirt MJ, Stanley S. Update on stress ulcer prophylaxis in critically ill patients. Crit Care Nurse. 2006; 26: 18-28.10.4037/ccn2006.26.1.18
]Search in Google Scholar
[
34. Laine L, Takeuchi K, Tarnawski A. Gastric mucosal defense and cytoprotection: bench to bedside. Gastroenterology. 2008; 135: 41-60.10.1053/j.gastro.2008.05.03018549814
]Search in Google Scholar
[
35. Sesler JM. Stress-related mucosal disease in the intensive care unit: an update on prophylaxis. AACN Adv Crit Care 2007; 18: 119-26.10.1097/01.AACN.0000269254.39967.8e17473539
]Search in Google Scholar
[
36. Spirt MJ. Stress-related mucosal disease: risk factors and prophylactic therapy. Clin Ther. 2004; 26: 197-213.10.1016/S0149-2918(04)90019-7
]Search in Google Scholar
[
37. Constantin VD, Paun S, Ciofoaia VV, Budu V, Socea B. Multimodal management of upper gastrointestinal bleeding caused by stress gastropathy. J Gastrointestin Liver Dis. 2009; 18(3): 279-84.
]Search in Google Scholar
[
38. Corley DA, Kubo A, Zhao W, Quesenberry C. Proton pump inhibitors and histamine-2 receptor antagonists are associated with hip fractures among at-risk patients. Gastroenterology. 2010; 139(1): 93-101.10.1053/j.gastro.2010.03.055290264920353792
]Search in Google Scholar
[
39. Morgan D. Intravenous proton pump inhibitors in the critical care setting. Crit Care Med. 2002; 30(6): S369-72.10.1097/00003246-200206001-0000712072664
]Search in Google Scholar
[
40. Balsells E, Filipescu T, Kyaw MH, Wiuff C, Campbell H, Nair H. Infection prevention and control of Clostridium difficile: a global review of guidelines, strategies, and recommendations. J Glob Health. 2016; 6(2): 020410.10.7189/jogh.06.020410514007428028434
]Search in Google Scholar