<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Mastocytosis refers to a group of diseases characterized by a clonal proliferation and accumulation of mast cells in one or more tissues/organs with different clinical presentations. In children, limited cutaneous forms of mastocytosis are rather frequent, while systemic mastocytosis is rare. The diagnosis of cutaneous mastocytosis is based on clinical findings and histopathology. We present a patient who developed skin lesions at the age of 18 months. Clinical findings, confirmed by histopathology, were consistent with diffuse cutaneous mastocytosis. The follow-up period was 7 years. The treatment included oral antihistamines in combination with mast cell stabilizers, mild topical steroids and avoidance of friction. During the follow-up period, there were no signs of systemic involvement, and the quality of life was preserved, despite the large surface of affected skin. This case report should increase the awareness and knowledge of clinicians about this rare form of cutaneous mastocytosis in the pediatric population.</p></abstract>

Mastocytosis refers to a group of diseases characterized by a clonal proliferation and accumulation of mast cells in one or more tissues/organs with different clinical presentations. In children, limited cutaneous forms of mastocytosis are rather frequent, while systemic mastocytosis is rare. The diagnosis of cutaneous mastocytosis is based on clinical findings and histopathology. We present a patient who developed skin lesions at the age of 18 months. Clinical findings, confirmed by histopathology, were consistent with diffuse cutaneous mastocytosis. The follow-up period was 7 years. The treatment included oral antihistamines in combination with mast cell stabilizers, mild topical steroids and avoidance of friction. During the follow-up period, there were no signs of systemic involvement, and the quality of life was preserved, despite the large surface of affected skin. This case report should increase the awareness and knowledge of clinicians about this rare form of cutaneous mastocytosis in the pediatric population.

Diffuse Cutaneous Mastocytosis in a Child - a Case Report

Clinic of Dermatovenereology, Clinical Center of Serbia

Department of Dermatovenereology, School of Medicine

Serbian Journal of Dermatology and Venereology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

{"article-title":"Diffuse Cutaneous Mastocytosis in a Child - a Case Report"}

Mastocytosis refers to a group of diseases characterized by a clonal proliferation and accumulation of mast cells in one or more tissues/organs with different...

Diffuse Cutaneous Mastocytosis in a Child - a Case Report

Pubblicato online: 24 mar 2018

Pagine: 124 - 128

DOI: https://doi.org/10.1515/sjdv-2017-0013

Parole chiave
Mastocytosis, Cutaneous, Child, Diagnosis, Signs and Symptoms, Mast Cells, Dermatologic Agents, Treatment Outcome

© 2017 Svetlana Popadić et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Diffuse Cutaneous Mastocytosis in a Child - a Case Report

Pubblicato online: 24 mar 2018

Pagine: 124 - 128

DOI: https://doi.org/10.1515/sjdv-2017-0013

Parole chiaveMastocytosis, Cutaneous, Child, Diagnosis, Signs and Symptoms, Mast Cells, Dermatologic Agents, Treatment Outcome

© 2017 Svetlana Popadić et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Parole chiave
Mastocytosis, Cutaneous, Child, Diagnosis, Signs and Symptoms, Mast Cells, Dermatologic Agents, Treatment Outcome