<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Hepatopulmonary syndrome (HPS) is a pulmonary complication of liver disease characterized by arterial hypoxemia. Mechanisms related to this event are diffusion-perfusion flaw, ventilation-perfusion (V/Q) mismatch, and direct arteriovenous shunts. Diagnosis of HPS is based on the presence of liver disease or portal hypertension, increased alveolar-arterial (A-a) PO<sub>2</sub>, and intrapulmonary vascular dilatations (IPVD). Lung transplantation (LT) remains the most effective therapy for HPS. In spite of its poor prognosis, we could improve the quality of life and survival rate of patients.</p></abstract>

Hepatopulmonary syndrome (HPS) is a pulmonary complication of liver disease characterized by arterial hypoxemia. Mechanisms related to this event are diffusion-perfusion flaw, ventilation-perfusion (V/Q) mismatch, and direct arteriovenous shunts. Diagnosis of HPS is based on the presence of liver disease or portal hypertension, increased alveolar-arterial (A-a) PO2, and intrapulmonary vascular dilatations (IPVD). Lung transplantation (LT) remains the most effective therapy for HPS. In spite of its poor prognosis, we could improve the quality of life and survival rate of patients.

Hepatopulmonary Syndrome: A Brief Review

Division of Respirology and Critical Care, Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia

Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia

Faculty of Medicine, University of Indonesia, Jakarta, Indonesia

Romanian Journal of Internal Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Hepatopulmonary Syndrome: A Brief Review"}

Hepatopulmonary syndrome (HPS) is a pulmonary complication of liver disease characterized by arterial hypoxemia. Mechanisms related to this event are...

Hepatopulmonary Syndrome: A Brief Review

Pubblicato online: 20 mag 2016

Pagine: 93 - 97

Ricevuto: 09 ott 2015

DOI: https://doi.org/10.1515/rjim-2016-0015

Parole chiave
Hepatopulmonary syndrome, liver cirrhosis, liver disease, lung disease, portal hypertension

© 2016 Zulkifli Amin et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Hepatopulmonary Syndrome: A Brief Review

Pubblicato online: 20 mag 2016

Pagine: 93 - 97

Ricevuto: 09 ott 2015

DOI: https://doi.org/10.1515/rjim-2016-0015

Parole chiaveHepatopulmonary syndrome, liver cirrhosis, liver disease, lung disease, portal hypertension

© 2016 Zulkifli Amin et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Parole chiave
Hepatopulmonary syndrome, liver cirrhosis, liver disease, lung disease, portal hypertension