Protective Effects of At1-Receptor Blocker and Ca Antagonist Combination on Renal Function in Salt Loaded Spontaneously Hypertensive Rats/ Протективни Ефекти На Комбинацијата На Ат1 Рецепторен Блокатор И Калциум Антагонист Врз Реналната Функција Кај Спонтано Хипертензивни Стаорци Оптоварени Со Сол

1. Campese VM. Salt sensitivity in hypertension. Renal and cardiovascular implications. Hypertension. 1994; 23: 531-50.10.1161/01.HYP.23.4.531Search in Google Scholar

2. Klag MJ, Whelton PK, Randall BL, Neaton JD, Brancati FL, Ford CE, Shulman NB, Stamler J. Blood pressure and end-stage renal disease in men. N Engl J Med. 1996; 334: 13-18.10.1056/NEJM199601043340103Search in Google Scholar

3. Frohlich E.D. The Salt Cohondrum A Hypothesis. Hypertension. 2007; 50: 161-6.10.1161/HYPERTENSIONAHA.107.088328Search in Google Scholar

4. Laverman GD, Remuzzi G, Ruggenenti P.ACE inhibition versus angiotensin receptor blockade: which is better for renal and cardiovascular protection. J Amer Soc Nephrol. 2004; 15: S64-S70.10.1097/01.ASN.0000093368.27046.3CSearch in Google Scholar

5. Berl T. Angiotensin-converting enzyme inhibitors versus AT1 antagonist in cardiovascular and renal protection: the case for AT1 receptor antagonist. J Amer Soc Nephrol. 2004; 15: S71-S76.10.1097/01.ASN.0000093235.09769.9CSearch in Google Scholar

6. Boffa J. Lu Y, Placier A, Stefanski A, Dussaule J, Chatziantoniou C. Reggression of renal and glomerular fibrosis: the rose of angiotensin IIreceptor antagonism andmatrix metalloproteinases. J Amer Soc Nephrol. 2003; 14: 1132-1144.10.1097/01.ASN.0000060574.38107.3BSearch in Google Scholar

7. Trippodo N.C, Frohlich E.D. Similarities of genetic (spontaneous) hypertension.Man and rat. Circ Res. 1981; 48: 309-19.Search in Google Scholar

8. Doggrell S.A, Brown L. Rat models of hypertension, cardiac hypertrophy and failure. Cardiovascular Research. 1998; 39: 89-105.10.1016/S0008-6363(98)00076-5Search in Google Scholar

9. Field LG, Van Liew JB, Galaske RG, Boylan JW, Chang H, Manz N, Muir P. Selectivity of renal injury and proteinuria in the spontaneously hypertensive rat. Kidney International. 1977; 12: 332-43.10.1038/ki.1977.120604622Search in Google Scholar

10. Katori M, Majima M. A missing link between a high salt intake and blood pressure increase. J Pharmacol Sci. 2006; 100: 370-90.10.1254/jphs.CRJ06003XSearch in Google Scholar

11. Susic D, Fares H, Frohlich E.D. Salt, Arterial pressure and cardiovascular and renal damage. Ochsner Journal. 2009; 9: 197-203.Search in Google Scholar

12. Yuan B, Leenen FHH. Dietary sodium intake and left ventricular hypertrophy in normotensive rats.Am J Physiol Heart Circ Physiol. 1991; 261: H1397- H1401.10.1152/ajpheart.1991.261.5.H13971835307Search in Google Scholar

13. Meulemans D. Determination of total protein in spinal fluid with sulphosalycilic acid and trichloroacetate. Clin Chim Acta. 1961; 5: 757-61.10.1016/0009-8981(60)90020-6Search in Google Scholar

14. Bartels H and Bohmer M. Serum creatinine determination without protein precipitation. Clin Chim Acta. 1972; 37: 193-97.10.1016/0009-8981(72)90432-9Search in Google Scholar

15. The effects of nonpharmacological interventions on blood pressure of persons with high normal levels: results of the Trials of Hypertension Prevention, Phase I [published correction appears in JAMA. 1992; 267(17): 2330]. JAMA 1992. 267 (9): 1213-1220.10.1001/jama.267.9.1213Search in Google Scholar

16. Trials of Hypertension Prevention Collaborative Research Group Effects of weight loss and sodium reduction intervention on blood pressure and hypertension incidence in overweight people with highnormal blood pressure: the Trials of Hypertension Prevention, phase II. Arch Intern Med. 1997; 157 (6): 657-67.10.1001/archinte.1997.00440270105009Search in Google Scholar

17. Bray GA, Vollmer WM, Sacks FM, Obarzanek E, Svetkey LP, Appel LJ. DASH Collaborative Research Group A further subgroup analysis of the effects of DASH diet and three dietary sodium levels on blood pressure: results of the DASH-Sodium Trial. Am J Cardiol. 2004. 94 (2): 222-227.10.1016/j.amjcard.2004.03.07015246908Search in Google Scholar

18. Sacks FM, Svetkey LP, Vollmer WM, et al. Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. N Engl J Med. 2001; 344 (1): 3-10.10.1056/NEJM20010104344010111136953Search in Google Scholar

19. Hooper L, Bartlett C, Davey Smith S, Ebrahim S. Systematic review of long-term effects of advice to reduce dietary salt in adults. BMJ. 2002; 325(7365): e628.10.1136/bmj.325.7365.62812630312242173Search in Google Scholar

20. Chrysant SG, Walsh GM, Frohlich ED. Hemodynamic changes induced by prolonged NaCl and DOCA administration in spontaneously hypertensive rats. Angiology. 1978; 29: 303-309.10.1177/000331977802900406655461Search in Google Scholar

21. Chrysant SG, Walsh GM, Kem DC, Frohlich ED. Hemodynamic and metabolic evidence of salt sensitivity in spontaneously hypertensive rats. Kidney Int’l. 1979; 15: 33-37.10.1038/ki.1979.4491394Search in Google Scholar

22. Frohlich ED, Chien Y, Sesoko S, Pegram BL. Relationship between dietary sodium intake, hemodynamics, and cardiac mass in SHR and WKY rats. Am J Physiol. (Regulatory Integrative 33). 1993; 264: R30-R34.10.1152/ajpregu.1993.264.1.R308430884Search in Google Scholar

23. Varagic J, Frohlich E.D, Diez J, Susic D, Ahn J, Gonsales A, Lopez B. Myocardial fibrosis, impared coronary hemodynamics and biventricular dysfunction in salt-loaded SHR.Am J Physiol Heart Cir Physiool. 2006; 290: H1503-1509.10.1152/ajpheart.00970.200516299266Search in Google Scholar

24. Limas C, Westrum B, Limas C.J, Cohn J.N. Effect of Salt on Vascular Lesions of Spontaneously Hypertensive Rats. Hypertension. 1980; 2: 477-89.10.1161/01.HYP.2.4.4777399629Search in Google Scholar

25. Cavanagh EM, Ferder LF, Ferder MD, Stella IY, Toblli JE, Inserra F. Vascular structure and oxidative stress in salt-loaded spontaneously hypertensive rats: effects of losartan and atenolol. Am J Hypertens. 2010; 23(12): 1318-25.10.1038/ajh.2010.16720706197Search in Google Scholar

26. Matavelli LC, Zhou X, Varagic J, Susic D, Frohlich ED. High-salt diet produces severe renal dysfunction independently of changes in arterial pressure in spontaneously hypertensive rats (SHR). Am J Physiol Heart, Circ Physiol. 2007; 292: H814-H819.10.1152/ajpheart.00671.200616997890Search in Google Scholar

27. Navar LG, Prieto-Carrasquero MC, Kobori H. Regulation of renin in JGA and tubules in hypertension. In: The Local Cardiac Renin AngiotensinAldosterone System, edited by Frohlich ED and Re RN. New York: Springer Science and Business Media. 2006; p. 45-59.10.1007/0-387-27826-5_5Search in Google Scholar

28. Nickenig G, Strehlow K, Roeling J, Zolk O, Knorr A, Bohm M. Salt induces AT1 receptor overexpression in vitro and in vivo.Hypertension. 1998; 31: 1272-77.10.1161/01.HYP.31.6.1272Search in Google Scholar

29. Schunkert H, Ingelfinger JR, Jacob H, Jackson B, Bouyounes B, Dzau VJ. Reciprocal feedback regulation of kidney angiotensinogen and renin mRNA expressions by angiotensin II. Am J Physiol Endocrinol Metab. 1992; 263: E863-E869.10.1152/ajpendo.1992.263.5.E8631443118Search in Google Scholar

30. Thomson SC, Deng A, Wead L, Richter K, Blantz RC, Vallon V. An unexpected role for angiotensin II in the link between dietary salt and proximal reabsorption. J Clin Invest. 2006; 116: 1110-116.10.1172/JCI26092140973916557296Search in Google Scholar

31. Varagic J. Salt-loading: a paradigm for a local cardiac renin-angiotensinaldosterone system. In: The Local Cardiac Renin Angiotensin-Aldosterone System, edited by Frohlich ED and Re RN. New York: Springer Science and Business Media. 2006; p. 61-72.10.1007/0-387-27826-5_6Search in Google Scholar

32. Susic D, Frohlich E.D. Telmisartan improves survival and ventricular function in SHR rats with extensive cardiovascular damage induced by dietary salt excess. J Am Soc Hypertens. 2014; 8 (5): 297-302. 10.1016/j.jash.2014.02.00924726099Search in Google Scholar