[1. Centers for Disease Control and Prevention. Compressed mortality file 1999-2011 [CD- ROM]. Atlanta: National Center for Health Statistics; 2014.]Search in Google Scholar
[2. National Oncological Hospital, Bulgarian National Cancer Resistry. Cancer Incidence in Bulgaria. Sofia: Paradigma; 2014, 170 p.]Search in Google Scholar
[3. Chilingirova N, Balabanski L, Toncheva D, Kurteva G, Damyanov D, Chilingirov P. Identifying the genetic landscape of squamous cell carcinoma (SCC) and adenosquamous carcinoma (ASC) of the lung using next- generation sequencing (NGS). Ann Oncol. 2015;26 Suppl: i1- i5.10.1093/annonc/mdv043.16]Search in Google Scholar
[4. Chilingirova N, Balabanski L, Kurteva G, Toncheva D, Damyanov D, Chilingirov P. Detection of driver mutation heterogeneity in patients with non-small cell lung cancer (NSCLC) using next generation sequencing (NGS). EJC. 2015;51 Suppl 3:S612-S613.10.1016/S0959-8049(16)31692-6]Search in Google Scholar
[5. Chilingirova N, Balabanski L, Ivanov S, Vazharova R, Toncheva D, Kurteva G. Detection of extensive driver mutation heterogeneity in 5 Bulgarian patients with adenosquamous carcinoma of the lung. Eur J Hum Genet. 2015;23(1).]Search in Google Scholar
[6. Chilingirova N. [Non-small cell lung cancer in the era of precision medicine]. INSPIRO. 2017;2(40):13-7. Bulgarian.]Search in Google Scholar
[7. Chilingirova N. [Role of tumor markers]. Rheumatology. 2013;21(1). Bulgarian.]Search in Google Scholar
[8. Chilingirova N, Kurteva G, Toncheva D. [Lung Cancer and genetics]. Oncology. 2015; 4:40. Bulgarian.]Search in Google Scholar
[9. Chilingirova N. [Lung Cancer - an overview]. Zdraven Navigator. 2017;3:2-4. Bulgarian.]Search in Google Scholar
[10. Rousseau B, Jacquot, C, Le Palabe J, Malleter M, Tomasoni C, Boutard T, et al. TP53 transcription factor for the NEDD9/HEF1/Cas-L gene: potential targets in Non-Small Cell Lung Cancer treatment. Sci Rep. 2015 May 26;5:10356.10.1038/srep10356]Search in Google Scholar
[11. Malumbres M, Barbacid M. RAS oncogenes: the first 30 years. Nat Rev Cancer. 2003;3(6):459- 65.10.1038/nrc1097]Search in Google Scholar
[12. Cardarella S, Ogino A, Nishino M, Butaney M, Shen J, Lydon C et al. Clinical, pathologic and biologic features associated with BRAF mutations in non-small cell lung cancer. Clin Cancer Res. 2013;19(16):4532-40.10.1158/1078-0432.CCR-13-0657]Search in Google Scholar
[13. Marchetti A, Felicioni L, Malatesta S, Grazia Sciarrotta M, Guetti L, Chella A, et al. Clinical features and outcome of patients with non-small- cell lung cancer harboring BRAF mutations. J Clin Oncol. 2011;29(26):3574-9.10.1200/JCO.2011.35.9638]Search in Google Scholar
[14. Hynes NE, Lane HA. ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer. 2005;5(5):341-4.10.1038/nrc1609]Search in Google Scholar
[15. Popovska S, Chilingirova N, Dineva T, Kamburova Z. Prevalence of epidermal growth factor receptor (EGFR) gene mutations in non-small cell lung cancer (NSCLC) in Bulgarian population, J Thorac Oncol. 2016;11(4);Suppl:S128-S129.10.1016/S1556-0864(16)30273-8]Search in Google Scholar
[16. Lampaki S, Lazaridis G, Zarogoulidis K, Kioumis I, Papaiwannou A, Tsirgogianni K, et al. Defining the role of tyrosine kinase inhibitors in early stage non-small cell lung cancer. J Cancer. 2015;6(6):568-74.10.7150/jca.11893443994326000049]Search in Google Scholar
[17. Vanderbilt-Ingram Cancer Center. Molecular Profiling of Lung Cancer [Internet]. Nashville; c2016. [cited 2018 Febr 18]. Available from: https://www.mycancergenome.org/content/disease/lung-cancer/.]Search in Google Scholar
[18. Huang L, Fu L. Mechanisms of resistance to EGFR tyrosine kinase inhibitors. Acta Pharm Sin B. 2015;5(5):390-401.10.1016/j.apsb.2015.07.001462944226579470]Search in Google Scholar
[19. Yu HA, Arcila ME, Rekhtman N, Sima CS, Zakowski MF, Pao W, et al. Analysis of tumor specimens at the time of acquired resistance to EGFR-TKI therapy in 155 patients with EGFR-mutant lung cancers. Clin Cancer Res. 2013;19(8):2240-7.10.1158/1078-0432.CCR-12-2246363027023470965]Search in Google Scholar
[20. Sandler A, Gray R, Perry MC, Brahmer J, Schiller JH, Dowlati A, et al. Paclitaxel– Carboplatin Alone or with Bevacizumab for Non-Small-Cell Lung Cancer. N Engl J Med. 2006;355(24):2542-50.10.1056/NEJMoa06188417167137]Search in Google Scholar
[21. Reck M, von Pawel J, Zatloukal P, Ramlau R, Gorbounova V, Hirsh V, et al. Overall survival with cisplatin-gemcitabine and bevacizumab or placebo as first-line therapy for nonsquamous non-small-cell lung cancer: results from a randomised phase III trial (AVAiL). Ann Oncol. 2010;21(9):1804-9.10.1093/annonc/mdq020292499220150572]Search in Google Scholar
[22. Reck M, von Pawel J, Zatloukal P, Ramlau R, Gorbounova V, Hirsh V, et al. Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAil. J Clin Oncol. 2009;27(8):1227-34.10.1200/JCO.2007.14.546619188680]Search in Google Scholar
[23. Scagliotti G, Hanna N, Fossella F, Sugarman K, Blatter J, Peterson P, et al. The differential efficacy of pemetrexed according to NSCLC histology: a review of two Phase III studies. Oncologist. 2009;14(3):253-63.10.1634/theoncologist.2008-023219221167]Search in Google Scholar
[24. Chilingirova N, Hammoudeh Z, Balabanski L, Ivanov S, Vazharova R, Nikolova D, et al. TruSight Cancer Sequencing Panel reveals pharmacogenetic variants associated with sensitivity to chemotherapy in lung cancer. memo-Magazine of European Medical Oncology. 2016; 9(1):30-8.10.1007/s12254-015-0244-2]Search in Google Scholar
[25. Chilingirova N, Kurteva G, Toncheva D. TruSight Cancer Sequencing Panel for detecting of driver mutation heterogeneity and pharmacogenetic variants associated with sensitivity to chemotherapy in patients with non-small cell lung cancer (NSCLC). Proceedings of the 8th National Conference for Rare Diseases and Orphan Drugs & 12th Balkan Congress of Human Genetics; 2017 Sept 8-10; Plovdiv, Bulgaria: Abstract book, p.67.]Search in Google Scholar
[26. Chilingirova N, Hammoudeh Z, Balabanski L, Ivanov S, Vazharova R, Nesheva D, et al. Pharmacogenomic study of non-small cell lung cancer. Eur J Hum Genet. 2015;23(1).]Search in Google Scholar
[27. Chilingirova N, Chilingirov N. [Pharmacogenetics and drug resistance in oncology]. Rheumatology. 2017 Dec: 35. Bulgarian.]Search in Google Scholar
[28. Tibaldi C, Giovannetti E, Vasile E, Mey V, Laan AC, Nannizzi S, et al. Correlation of CDA, ERCC1, and XPD polymorphisms with response and survival in gemcitabine/cisplatin- treated advanced non-small cell lung cancer patients. Clin Cancer Res. 2008;14(6):1797-3.10.1158/1078-0432.CCR-07-136418347182]Search in Google Scholar
[29. Chilingirova N, Chilingirov N. [Therapy related side effects in the treatment of lung cancer]. Rheumatology. 2017 Dec; 1:47. Bulgarian.]Search in Google Scholar
[30. Chilingirova N. [Mucositis]. In: [Kurteva G, Trifonova I, editors. Treatment related side effects]. Sofia; 2017. p. 149-163. Bulgarian.]Search in Google Scholar
[31. Hrstka R, Coates PJ, VoJtesek B. Polymorphisms in p53 and the p53 pathway: roles in cancer susceptibility and response to treatment. J Cell Mol Med. 2009;13(3):440-53.10.1111/j.1582-4934.2008.00634.x382250719379143]Search in Google Scholar
[32. Dumont P, Leu JI, Della Pietra AC 3rd, George DL, Murphy M. The codon 72 polymorphic variants of p53 have markedly different apoptotic potential. Nat Genet. 2003;33(3):357- 65.10.1038/ng109312567188]Search in Google Scholar
[33. Liu L, Wu C, Wang Y, Zhong R, Duan S, Wei S, et al. Combined effect of genetic polymorphisms in P53, P73, and MDM2 on non-small cell lung cancer survival. J Thorac Oncol. 2011;6(11):1793-800.10.1097/JTO.0b013e318227227321841506]Search in Google Scholar