<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Sulfanilic acid represents an important substance, which is frequently utilized in the industry of azo dyes as well as in drug development of antimicrobials (e.g. of sulfonamides). Students can also meet with such type of compounds in chemistry labs, for example, when they estimate pH by methyl orange indicator or prepare Orange II for textile colouring. Both of these dyes are products of azo coupling of sulfanilic acid as diazonium salt with <italic>N,N</italic>-dimethylaniline or 2-naphthol, respectively. In the article, we focus on the synthesis of sulfanilic acid as a well-known experiment in the organic chemistry education. The synthesis was modified as the solvent free and microwave assisted experiment under semimicroscale conditions. That experiment is very convenient for the organic chemistry courses in the university or the high school teaching.</p></abstract>

Sulfanilic acid represents an important substance, which is frequently utilized in the industry of azo dyes as well as in drug development of antimicrobials (e.g. of sulfonamides). Students can also meet with such type of compounds in chemistry labs, for example, when they estimate pH by methyl orange indicator or prepare Orange II for textile colouring. Both of these dyes are products of azo coupling of sulfanilic acid as diazonium salt with N,N-dimethylaniline or 2-naphthol, respectively. In the article, we focus on the synthesis of sulfanilic acid as a well-known experiment in the organic chemistry education. The synthesis was modified as the solvent free and microwave assisted experiment under semimicroscale conditions. That experiment is very convenient for the organic chemistry courses in the university or the high school teaching.

Microwave synthesis of sulfanilic acid

Department of Chemistry, Faculty of Natural Sciences

Department of Chemistry, Institute of Biology

State Budget Institute of Professional Education

Chemistry-Didactics-Ecology-Metrology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Microwave synthesis of sulfanilic acid"}

Sulfanilic acid represents an important substance, which is frequently utilized in the industry of azo dyes as well as in drug development of antimicrobials...

Microwave synthesis of sulfanilic acid

Pubblicato online: 27 gen 2018

Pagine: 93 - 98

DOI: https://doi.org/10.1515/cdem-2017-0005

Parole chiave
synthesis of sulfanilic acid, microwave assisted synthesis, solvent-free synthesis, school experiment, organic chemistry education

© 2017 Jiří Havlíček et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Microwave synthesis of sulfanilic acid

Pubblicato online: 27 gen 2018

Pagine: 93 - 98

DOI: https://doi.org/10.1515/cdem-2017-0005

Parole chiavesynthesis of sulfanilic acid, microwave assisted synthesis, solvent-free synthesis, school experiment, organic chemistry education

© 2017 Jiří Havlíček et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Parole chiave
synthesis of sulfanilic acid, microwave assisted synthesis, solvent-free synthesis, school experiment, organic chemistry education