Genotype | Control Group | Patient Group | OR Value | 95% CI | |||
---|---|---|---|---|---|---|---|
% | % | ||||||
593 | 79.00 | 463 | 61.73 | 1.00 | 1.86-2.95 | <0.01 | |
605 | 80.67 | 380 | 50.67 | 1.00 | 3.23-5.12 | <0.01 | |
598 | 79.73 | 395 | 52.67 | 1.00 | 2.81-43.44 | <0.01 | |
419 | 55.87 | 231 | 30.80 | 1.00 | 1.95-4.47 | <0.01 | |
444 | 55.60 | 212 | 30.53 | 1.00 | 2.97-4.57 | <0.01 |
Number of | Smoking | Control Group | Patient Group | OR Value | 95% CI | |||
---|---|---|---|---|---|---|---|---|
% | % | |||||||
0 | ≤400 | 45 | 6.00 | 2 | 0.27 | 1.00 | – | – |
1 | ≤400 | 54 | 7.20 | 16 | 2.13 | 0.22 | 0.05-1.00 | 0.07 |
2 | ≤400 | 45 | 6.00 | 23 | 3.07 | 0.38 | 0.08-1.86 | 0.23 |
3 | ≤400 | 33 | 4.40 | 44 | 5.87 | 1.00 | 1.00-0.21 | 1.00 |
4 | ≤400 | 23 | 3.07 | 32 | 4.27 | 1.04 | 0.21-5.12 | 0.96 |
5 | ≤400 | 2 | 0.27 | 3 | 0.40 | 1.12 | 0.11-11.60 | 0.92 |
0 | 400 | 3 | 0.40 | 4 | 0.53 | 1.82 | 0.51-2.85 | 0.49 |
1 | 400 | 45 | 6.00 | 24 | 3.20 | 1.80 | 0.85-3.80 | 0.12 |
2 | 400 | 28 | 3.73 | 123 | 16.40 | 8.60 | 4.50-16.44 | <0.01 |
3 | 400 | 11 | 1.47 | 153 | 20.40 | 10.43 | 4.88-22.31 | <0.01 |
4 | 400 | 9 | 1.20 | 57 | 7.60 | 4.55 | 1.88-11.02 | <0.01 |
5 | 400 | 1 | 0.13 | 4 | 0.53 | 2.67 | 0.16-45.14 | 0.50 |
Number of | Smoking | Drinking | Controls | Patients | OR | 95% CI | |||
---|---|---|---|---|---|---|---|---|---|
% | % | ||||||||
0 | [–] | [–] | 68 | 9.07 | 15 | 2.00 | 1.00 | – | – |
1 | [–] | [–] | 82 | 10.93 | 12 | 1.60 | 1.04 | 0.64-1.70 | 0.86 |
2 | [–] | [–] | 48 | 6.40 | 42 | 5.60 | 2.22 | 1.44-3.44 | <0.01 |
3 | [–] | [–] | 27 | 3.60 | 21 | 2.80 | 2.14 | 1.31-3.50 | <0.01 |
4 | [–] | [–] | 18 | 2.40 | 18 | 2.40 | 3.30 | 1.91-5.67 | <0.01 |
5 | [–] | [–] | 1 | 0.13 | 1 | 0.13 | 0.41 | 0.09-1.87 | 0.25 |
0 | [–] | [+] | 24 | 3.20 | 16 | 2.13 | 1.91 | 0.31-11.81 | 0.48 |
1 | [–] | [+] | 36 | 4.80 | 31 | 4.13 | 7.07 | 4.38-11.42 | <0.01 |
2 | [–] | [+] | 68 | 9.07 | 48 | 6.40 | 2.45 | 1.66-3.63 | <0.01 |
3 | [–] | [+] | 44 | 5.87 | 32 | 4.27 | 1.66 | 1.02-2.69 | 0.04 |
4 | [–] | [+] | 22 | 2.93 | 28 | 3.73 | 2.05 | 1.17-3.60 | 0.01 |
5 | [–] | [+] | 13 | 1.73 | 1 | 0.13 | 2.16 | 0.32-14.40 | 0.43 |
0 | [+] | [–] | 32 | 4.27 | 12 | 1.60 | 0.86 | 0.16-4.63 | 0.87 |
1 | [+] | [–] | 84 | 11.20 | 30 | 4.00 | 2.53 | 1.51-3.96 | <0.01 |
2 | [+] | [–] | 57 | 7.60 | 35 | 4.67 | 2.43 | 1.65-3.58 | <0.01 |
3 | [+] | [–] | 24 | 3.20 | 44 | 5.87 | 4.90 | 2.92-8.21 | <0.01 |
4 | [+] | [–] | 25 | 3.33 | 25 | 3.33 | 1.60 | 0.91-2.80 | 0.10 |
5 | [+] | [–] | 2 | 0.27 | 1 | 0.13 | 32.20 | 5.49-188.91 | <0.01 |
0 | [+] | [+] | 5 | 0.67 | 2 | 0.27 | 3.45 | 1.62-5.41 | <0.01 |
1 | [+] | [+] | 16 | 2.13 | 62 | 8.27 | 10.36 | 6.53-16.44 | <0.01 |
2 | [+] | [+] | 21 | 2.80 | 112 | 14.93 | 6.20 | 4.12-9.33 | <0.01 |
3 | [+] | [+] | 11 | 1.47 | 84 | 11.20 | 5.23 | 3.33-820 | <0.01 |
4 | [+] | [+] | 19 | 2.53 | 56 | 7.47 | 4.19 | 2.67-6.58 | <0.01 |
5 | [+] | [+] | 3 | 0.40 | 22 | 2.93 | 13.26 | 4.09-42.97 | <0.01 |
Number of | Smoking | Control Group | Patient Group | OR Value | 95% CI | |||
---|---|---|---|---|---|---|---|---|
% | % | |||||||
0 | [–] | 92 | 12.27 | 31 | 4.13 | 1.00 | – | – |
1 | [–] | 118 | 15.73 | 43 | 5.73 | 1.04 | 0.64-1.70 | 0.86 |
2 | [–] | 116 | 15.47 | 90 | 12.00 | 2.22 | 1.44-3.44 | <0.01 |
3 | [–] | 71 | 9.47 | 53 | 7.07 | 2.14 | 1.31-3.50 | <0.01 |
4 | [–] | 40 | 5.33 | 46 | 6.13 | 3.30 | 1.92-5.67 | <0.01 |
5 | [–] | 14 | 1.87 | 2 | 0.27 | 0.41 | 0.09-1.87 | 0.25 |
0 | [+] | 37 | 4.93 | 14 | 1.87 | 0.89 | 0.43-1.86 | 0.76 |
1 | [+] | 100 | 13.33 | 92 | 12.27 | 2.52 | 1.61-3.96 | <0.01 |
2 | [+] | 78 | 10.40 | 147 | 19.60 | 2.43 | 1.65-3.58 | <0.01 |
3 | [+] | 35 | 4.67 | 128 | 17.07 | 4.90 | 2.92-8.21 | <0.01 |
4 | [+] | 44 | 5.87 | 81 | 10.80 | 1.60 | 0.91-2.80 | 0.10 |
5 | [+] | 5 | 0.67 | 23 | 3.07 | 32.20 | 5.49-118-91 | <0.01 |
Number of | Drinking | Control Group | Patient Group | OR Value | 95% CI | |||
---|---|---|---|---|---|---|---|---|
% | % | |||||||
0 | ≤3000 | 21 | 2.80 | 3 | 0.40 | 1.00 | – | – |
1 | ≤3000 | 47 | 6.27 | 15 | 2.00 | 0.80 | 0.01-077 | 0.03 |
2 | ≤3000 | 49 | 6.53 | 26 | 3.47 | 0.13 | 0.01-1.25 | 0.08 |
3 | ≤3000 | 36 | 4.80 | 38 | 5.07 | 0.26 | 0.03-2.47 | 3.79 |
4 | ≤3000 | 16 | 2.13 | 28 | 3.73 | 0.44 | 0.05-4.26 | 0.48 |
5 | ≤3000 | 3 | 0.40 | 4 | 0.53 | 0.33 | 0.02-4.74 | 0.42 |
0 | 3000 | 1 | 0.13 | 4 | 0.53 | 2.96 | 0.55-6.28 | 0.08 |
1 | 3000 | 24 | 3.20 | 44 | 5.87 | 5.74 | 2.67-12.35 | <0.01 |
2 | 3000 | 39 | 5.20 | 122 | 16.27 | 5.90 | 3.27-10.71 | <0.01 |
3 | 3000 | 30 | 4.00 | 138 | 18.40 | 4.36 | 2.38-7.97 | <0.01 |
4 | 3000 | 14 | 1.87 | 54 | 7.20 | 2.20 | 0.94-5.16 | 0.07 |
5 | 3000 | 2 | 0.27 | 18 | 2.40 | 6.75 | 0.83-54.66 | 0.07 |
Characteristics | Control Group | Patient Group | OR Value | 95% CI | ||
---|---|---|---|---|---|---|
Sex | males | 498 (66.40%) | 504 (67.20%) | 0.97 | 0.78-1.20 | >0.05 |
Age | years; mean±SD | 55.51±4.42 | 55.49±4.33 | – | – | >0.05 |
Smoking status | non-smoker | 451 (60.13%) | 265 (35.33%) | 2.76 | 2.24-3.40 | <0.01 |
Drinking status | did not drink | 468 (62.40%) | 256 (34.13%) | 3.20 | 2.59-3.96 | <0.01 |
Number of | Control Group | Patient Group | OR Value | 95% CI | |||
---|---|---|---|---|---|---|---|
% | % | ||||||
0 | 97 | 12.93 | 8 | 1.07 | 1.00 | – | <0.01 |
1 | 290 | 38.67 | 64 | 8.53 | 2.68 | 1.23-5.78 | – |
2 | 210 | 28.00 | 230 | 30.67 | 13.28 | 6.31-27.97 | – |
3 | 90 | 12.00 | 278 | 37.07 | 37.45 | 17.53-80.02 | – |
4 | 56 | 7.47 | 156 | 20.80 | 33.78 | 15.44-73.90 | – |
5 | 7 | 0.93 | 14 | 1.86 | 24.25 | 7.61-77.27 | – |
Number of | Drinking | Control Group | Patient Group | OR Value | 95% CI | |||
---|---|---|---|---|---|---|---|---|
% | % | |||||||
0 | [–] | 100 | 13.33 | 27 | 3.60 | 1.00 | – | – |
1 | [–] | 166 | 22.13 | 42 | 5.60 | 0.41 | 0.21-0.80 | 0.01 |
2 | [–] | 105 | 14.00 | 77 | 10.27 | 1.18 | 0.61-2.28 | 0.62 |
3 | [–] | 51 | 6.80 | 65 | 8.67 | 2.05 | 1.03-4.11 | 0.04 |
4 | [–] | 43 | 5.73 | 43 | 5.73 | 1.61 | 0.78-3.32 | 0.20 |
5 | [–] | 3 | 0.40 | 2 | 0.27 | 1.07 | 0.16-7.06 | 0.94 |
0 | [+] | 29 | 3.87 | 18 | 2.40 | 0.44 | 0.21-0.90 | 0.03 |
1 | [+] | 52 | 6.93 | 93 | 12.40 | 7.07 | 4.38-11.42 | <0.01 |
2 | [+] | 89 | 11.87 | 160 | 21.33 | 2.45 | 1.66-3.63 | <0.01 |
3 | [+] | 55 | 7.33 | 116 | 15.47 | 1.66 | 1.02-2.69 | 0.04 |
4 | [+] | 41 | 5.47 | 84 | 11.20 | 2.05 | 1.67-3.60 | 0.01 |
5 | [+] | 16 | 2.13 | 23 | 3.07 | 2.16 | 0.32-14.41 | 0.43 |