This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Cybulsky MI, Gimbrone MA. Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science. 1991; 251(4995): 788-791.CybulskyMIGimbroneMA.Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis1991251499578879110.1126/science.19904401990440Search in Google Scholar
Peter K, Nawroth P, Conradt C, Nordt T, Weiss T, Boehme M, et al. Circulating vascular cell adhesion molecule-1 correlates with the extent of human atherosclerosis in contrast to circulating intercellular adhesion molecule-1, E-selectin, P-selectin, and thrombomodulin. Arterioscler Thromb Vasc Biol. 1997; 17(3): 505-512.PeterKNawrothPConradtCNordtTWeissTBoehmeMet al.Circulating vascular cell adhesion molecule-1 correlates with the extent of human atherosclerosis in contrast to circulating intercellular adhesion molecule-1, E-selectin, P-selectin, and thrombomodulin199717350551210.1161/01.ATV.17.3.505Search in Google Scholar
Hwang S-J, Ballantyne CM, Sharrett AR, Smith LC, Davis CE, Gotto AM Jr, et al. Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases. The Atherosclerosis Risk In Communities (ARIC) Study. Circulation. 1997; 96(12): 4219-4225.HwangS-JBallantyneCMSharrettARSmithLCDavisCEGottoAMJret al.Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases. The Atherosclerosis Risk In Communities (ARIC) Study199796124219422510.1161/01.CIR.96.12.4219Search in Google Scholar
Rohde LE, Lee RT, Rivero J, Jamacochian M, Arroyo LH, Briggs W, et al. Circulating cell adhesion molecules are correlated with ultrasound-based assessment of carotid atherosclerosis. Arterioscler Thromb Vasc Biol. 1998; 18(11): 1765-1770.RohdeLELeeRTRiveroJJamacochianMArroyoLHBriggsWet al.Circulating cell adhesion molecules are correlated with ultrasound-based assessment of carotid atherosclerosis199818111765177010.1161/01.ATV.18.11.17659812916Search in Google Scholar
Albelda SM, Oliver PD, Romer LH, Buck CA. EndoCAM: A novel endothelial cell-cell adhesion molecule. J Cell Biol. 1990; 110(4): 1227-1237.AlbeldaSMOliverPDRomerLHBuckCA.EndoCAM: A novel endothelial cell-cell adhesion molecule199011041227123710.1083/jcb.110.4.122721160642182647Search in Google Scholar
Newman PJ, Berndt MC, Gorski J, White GC 2nd, Lyman S, Paddock C, et al. PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. Science. 1990; 247(4947): 1219-1222.NewmanPJBerndtMCGorskiJWhiteGC2ndLymanSPaddockCet al.PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily199024749471219122210.1126/science.16904531690453Search in Google Scholar
Cicmil M, Thomas JM, Sage T, Barry FA, Leduc M, Bon C, et al. Collagen, convulxin, and thrombin stimulate aggregation-independent tyrosine phosphorylation of CD31 in platelets. Evidence for the involvement of Src family kinases. J Biol Chem. 2000; 275(35): 27339-27347.CicmilMThomasJMSageTBarryFALeducMBonCet al.Collagen, convulxin, and thrombin stimulate aggregation-independent tyrosine phosphorylation of CD31 in platelets. Evidence for the involvement of Src family kinases200027535273392734710.1074/jbc.M00319620010858437Search in Google Scholar
Falati S, Patil S, Gross PL, Stapleton M, Merrill-Skoloff G, Barrett NE, et al. Platelet PECAM-1 inhibits thrombus formation in vivo. Blood. 2006; 107(2): 535-541.FalatiSPatilSGrossPLStapletonMMerrill-SkoloffGBarrettNEet al.Platelet PECAM-1 inhibits thrombus formation in vivo2006107253554110.1182/blood-2005-04-1512189561016166583Search in Google Scholar
Matsumura T, Wolff K, Petzelbauer P. Endothelial cell tube formation depends on cadherin 5 and CD31 interactions with filamentous actin. J Immunol. 1997; 158(7): 3408-3416.MatsumuraTWolffKPetzelbauerP.Endothelial cell tube formation depends on cadherin 5 and CD31 interactions with filamentous actin199715873408341610.4049/jimmunol.158.7.3408Search in Google Scholar
Breier G, Breviario F, Caveda L, Berthier R, Schnüch H, Gotsch U, et al. Molecular cloning and expression of murine vascular endothelialcadherin in early stage development of cardiovascular system. Blood. 1996; 87(2): 630-641.BreierGBreviarioFCavedaLBerthierRSchnüchHGotschUet al.Molecular cloning and expression of murine vascular endothelialcadherin in early stage development of cardiovascular system199687263064110.1182/blood.V87.2.630.bloodjournal872630Search in Google Scholar
Newton-Nash DK, Newman PJ. A new role for platelet-endothelial cell adhesion molecule-1 (CD31): inhibition of TCR-mediated signal transduction. J Immu-nol. 1999; 163(2): 682-688.Newton-NashDKNewmanPJ.A new role for platelet-endothelial cell adhesion molecule-1 (CD31): inhibition of TCR-mediated signal transduction1999163268268810.4049/jimmunol.163.2.682Search in Google Scholar
Duncan GS, Andrew DP, Takimoto H, Kaufman SA, Yoshida H, Spellberg J, et al. Genetic evidence for functional redundancy of platelet/endothelial cell adhesion molecule-1 (PECAM-1): CD31-deficient mice reveal PECAM-1-dependent and PECAM-1-independent func-tions. J Immunol. 1999; 162(5): 3022-3030.DuncanGSAndrewDPTakimotoHKaufmanSAYoshidaHSpellbergJet al.Genetic evidence for functional redundancy of platelet/endothelial cell adhesion molecule-1 (PECAM-1): CD31-deficient mice reveal PECAM-1-dependent and PECAM-1-independent func-tions199916253022303010.4049/jimmunol.162.5.3022Search in Google Scholar
Behar E, Chao NJ, Hiraki DD, Krishnaswamy S, Brown BW, Zehnder JL, et al. Polymorphism of adhesion molecule CD31 and its role in acute graft-versus-host disease. N Engl J Med. 1996; 334(5): 286-291.BeharEChaoNJHirakiDDKrishnaswamySBrownBWZehnderJLet al.Polymorphism of adhesion molecule CD31 and its role in acute graft-versus-host disease1996334528629110.1056/NEJM199602013340502Search in Google Scholar
Muller WA, Weigl SA, Deng X, Phillips DM. PECAM-1 is required for transendothelial migration of leukocytes. J Exp Med. 1993; 178(2): 449-460.MullerWAWeiglSADengXPhillipsDM.PECAM-1 is required for transendothelial migration of leukocytes1993178244946010.1084/jem.178.2.449Search in Google Scholar
Sun J, Williams J, Yan HC, Amin KM, Albelda SM, DeLisser HM. Platelet endothelial cell adhesion molecule-1 (PECAM-1) homophilic adhesion is mediated by immunoglobulin-like domains 1 and 2 and depends on the cytoplasmic domain and the level of surface expression. J Biol Chem. 1996; 271(31): 18561-18570.SunJWilliamsJYanHCAminKMAlbeldaSMDeLisserHM.Platelet endothelial cell adhesion molecule-1 (PECAM-1) homophilic adhesion is mediated by immunoglobulin-like domains 1 and 2 and depends on the cytoplasmic domain and the level of surface expression199627131185611857010.1074/jbc.271.31.18561Search in Google Scholar
Reschner H, Milutinovic A, Petrovic D. The PE-CAM-1 gene polymorphism - A genetic marker of myocardial infarction. Cent Eur J Biol. 2009; 4(4): 515-520.ReschnerHMilutinovicAPetrovicD.The PE-CAM-1 gene polymorphism - A genetic marker of myocardial infarction200944515520Search in Google Scholar
Wenzel K, Baumann G, Felix SB. The homozygous combination of Leu125Val and Ser563Asn polymorphisms in the PECAM1 (CD31) gene is associated with early severe coronary heart disease. Hum Mutat. 1999; 14(6): 545.WenzelKBaumannGFelixSB.The homozygous combination of Leu125Val and Ser563Asn polymorphisms in the PECAM1 (CD31) gene is associated with early severe coronary heart disease199914654510.1002/(SICI)1098-1004(199912)14:6<545::AID-HUMU20>3.0.CO;2-5Search in Google Scholar
Gardemann A, Knapp A, Katz N, Tillmanns H, Haberbosch W. No evidence for the CD31 C/G gene polymorphism as an independent risk factor of coronary heart disease. Thromb Haemost. 2000; 83(4): 629.GardemannAKnappAKatzNTillmannsHHaberboschW.No evidence for the CD31 C/G gene polymorphism as an independent risk factor of coronary heart disease200083462910.1055/s-0037-1613875Search in Google Scholar
Sasaoka T, Kimura A, Hohta SA, Fukuda N, Kurosawa T, Izumi T. Polymorphisms in the platelet-endothelial cell adhesion molecule-1 (PECAM-1) gene, Asn563 Ser and Gly670Arg, associated with myocardial infarction in the Japanese. Ann NY Acad Sci. 2001; 947: 259-269; discussion 269-270.SasaokaTKimuraAHohtaSAFukudaNKurosawaTIzumiT.Polymorphisms in the platelet-endothelial cell adhesion molecule-1 (PECAM-1) gene, Asn563 Ser and Gly670Arg, associated with myocardial infarction in the Japanese2001947259269discussion 269-27010.1111/j.1749-6632.2001.tb03948.xSearch in Google Scholar
Wei H, Fang L, Chowdhury SH, Gong N, Xiong Z, Song J, et al. Platelet-endothelial cell adhesion molecule-1 gene polymorphism and its soluble level are associated with severe coronary artery stenosis in Chinese Singaporean. Clin Biochem. 2004; 37(12): 1091-1097.WeiHFangLChowdhurySHGongNXiongZSongJet al.Platelet-endothelial cell adhesion molecule-1 gene polymorphism and its soluble level are associated with severe coronary artery stenosis in Chinese Singaporean200437121091109710.1016/j.clinbiochem.2004.08.006Search in Google Scholar
Fleming I, Fisslthaler B, Dixit M, Busse R. Role of PECAM-1 in the shear-stress-induced activation of Akt and the endothelial nitric oxide synthase (eNOS) in endothelial cells. J Cell Sci. 2005; 118(Pt 18): 4103-4111.FlemingIFisslthalerBDixitMBusseR.Role of PECAM-1 in the shear-stress-induced activation of Akt and the endothelial nitric oxide synthase (eNOS) in endothelial cells2005118Pt 184103411110.1242/jcs.02541Search in Google Scholar
Bagi Z, Frangos JA, Yeh JC, White CR, Kaley G, Koller A. PECAM-1 mediates NO-dependent dilation of arterioles to high temporal gradients of shear stress. Arterioscler Thromb Vasc Biol. 2005; 25(8): 1590-1595.BagiZFrangosJAYehJCWhiteCRKaleyGKollerA.PECAM-1 mediates NO-dependent dilation of arterioles to high temporal gradients of shear stress20052581590159510.1161/01.ATV.0000170136.71970.5fSearch in Google Scholar
DeBakey ME, Lawrie GM, Glaeser DH. Patterns of atherosclerosis and their surgical significance. Ann Surg. 1985; 201(2): 115-131.DeBakeyMELawrieGMGlaeserDH.Patterns of atherosclerosis and their surgical significance1985201211513110.1097/00000658-198502000-00001Search in Google Scholar
Bao X, Lu C, Frangos JA. Temporal gradient in shear but not steady shear stress induces PDGFA and MCP-1 expression in endothelial cells: role of NO, NF kappa B, and egr-1. Arterioscler Thromb Vasc Biol. 1999; 19(4): 996-1003.BaoXLuCFrangosJA.Temporal gradient in shear but not steady shear stress induces PDGFA and MCP-1 expression in endothelial cells: role of NO, NF kappa B, and egr-11999194996100310.1161/01.ATV.19.4.996Search in Google Scholar
American Diabetes Association. Diagnosis and Classification of Diabetes Mellitus. Diabetes Care. 2012; 35(Suppl 1): S64-S71 (http://dx.doi.org/10.2337/dc12-s064).American Diabetes AssociationDiagnosis and Classification of Diabetes Mellitus201235Suppl 1S64S71http://dx.doi.org/10.2337/dc12-s064Open DOISearch in Google Scholar
Serebruany VL, Murugesan SR, Pothula A, Atar D, Lowry DR, O’Connor CM, et al. Increased soluble platelet/endothelial cellular adhesion molecule-1 and osteonectin levels in patients with severe congestive heart failure. Independence of disease etiology, and antecedent aspirin therapy. Eur J Heart Fail. 1999; 1(3): 243-249.SerebruanyVLMurugesanSRPothulaAAtarDLowryDRO’ConnorCMet al.Increased soluble platelet/endothelial cellular adhesion molecule-1 and osteonectin levels in patients with severe congestive heart failure. Independence of disease etiology, and antecedent aspirin therapy19991324324910.1016/S1388-9842(99)00029-XSearch in Google Scholar
Shalia KK, Mashru MR, Soneji SL, Shah VK, Payannavar S, Walvalkar A, et al. Leucine-125Valine (Leu 125Val) gene polymorphism of platelet endothelial cell adhesion molecule-1 (PECAM-1) and myocardial infarction in Indian Population. Ind J Clin Biochem. 2010; 25(3): 273-279.ShaliaKKMashruMRSonejiSLShahVKPayannavarSWalvalkarAet al.Leucine-125Valine (Leu 125Val) gene polymorphism of platelet endothelial cell adhesion molecule-1 (PECAM-1) and myocardial infarction in Indian Population201025327327910.1007/s12291-010-0063-5300183421731198Search in Google Scholar
Fang L, Wei H, Chowdhury SH, Gong N, Song J, Heng CK, et al. Association of Leu125Val polymorphism of platelet endothelial cell adhesion molecule-1 (PECAM-1) gene & soluble level of PECAM-1 with coronary artery disease in Asian Indians. Indian J Med Res. 2005; 121(2): 92-99.FangLWeiHChowdhurySHGongNSongJHengCKet al.Association of Leu125Val polymorphism of platelet endothelial cell adhesion molecule-1 (PECAM-1) gene & soluble level of PECAM-1 with coronary artery disease in Asian Indians200512129299Search in Google Scholar
Listi F, Caruso C, Di Carlo D, Falcone C, Boiocchi C, Cuccia M, et al. Association between platelet endothelial cellular adhesion molecule-1 polymorphisms and atherosclerosis: results of a study on patients from northern Italy. Rejuvenation Res. 2010; 13(2-3): 237-241.ListiFCarusoCDi CarloDFalconeCBoiocchiCCucciaMet al.Association between platelet endothelial cellular adhesion molecule-1 polymorphisms and atherosclerosis: results of a study on patients from northern Italy2010132-323724110.1089/rej.2009.094020370486Search in Google Scholar
Xia T, Liu X, Jiang CD, Jin X, Kong XQ, Li G. Association of Leu125Val polymorphisms in the PECAM-1 gene with the risk of coronary heart disease: a meta-analysis. Int J Clin Exp Med. 2015; 8(2): 2219-2225.XiaTLiuXJiangCDJinXKongXQLiG.Association of Leu125Val polymorphisms in the PECAM-1 gene with the risk of coronary heart disease: a meta-analysis20158222192225Search in Google Scholar
Moreno PR, Fuster V. New aspects in the pathogenesis of diabetic atherothrombosis. J Am Coll Cardiol. 2004; 44(12): 2293-2300.MorenoPRFusterV.New aspects in the pathogenesis of diabetic atherothrombosis200444122293230010.1016/j.jacc.2004.07.06015607389Search in Google Scholar
Grundy SM, Benjamin IJ, Burke GL, Chait A, Eckel RH, Howard BV, et al. Diabetes and cardiovascular disease: a statement for healthcare professionals from the American Heart Association. Circulation. 1999; 100(10): 1134-1146.GrundySMBenjaminIJBurkeGLChaitAEckelRHHowardBVet al.Diabetes and cardiovascular disease: a statement for healthcare professionals from the American Heart Association1999100101134114610.1161/01.CIR.100.10.1134Search in Google Scholar