Parameters/Clinical Indicator | % | |
---|---|---|
A thyroid disease | 19 | 6.1 |
Hor | 40 | 12.5 |
Est | 22 | 6.9 |
Prog | 3 | 0.9 |
An autoimmune disease | 6 | 1.9 |
PCOS | 18 | 5.6 |
BMI | 44 | 13.8 |
Males | Females | χ2 | ||||
---|---|---|---|---|---|---|
Mutations | % | % | ||||
c.290-13A/C>G | 2 | 0.6 | 2 | 0.6 | 0.043 | 0.979 |
p.I172N | 2 | 0.6 | 2 | 0.6 | 1.389 | 0.499 |
p.P30L | 0 | 0.0 | 0 | 0.0 | 0.000 | |
p.V281L | 1 | 0.3 | 0 | 0.0 | 1.405 | 0.495 |
Total | 5 | 1.6 | 4 | 1.3 | 2.254 | 0.324 |
Mutations | Probands ( | Controls ( | χ2 | |
---|---|---|---|---|
c.290-13A/C>G | 4 (0.6) | 1 (0.5) | 0.043 | 0.836 |
p.I172N | 4 (0.6) | 3 (1.5) | 1.389 | 0.239 |
p.P30L | 0 (0.0) | 1 (0.5) | 3.183 | 0.074 |
p.V281L | 1 (0.2) | 1 (0.5) | 0.749 | 0.387 |
Total | 9 (1.4) | 6 (3.0) | 2.167 | 0.141 |
Total | Males | Females | |
---|---|---|---|
638 | 319 | 319 | |
Mean age | 32.9 | 33.8 | 32.0 |
Age range (years) | 21-44 | 23-44 | 21-44 |
Clinical Parameters | c.290-13A/C>G (χ2; | p.I172N (χ2; | p.P30L (χ2; | p.V281L (χ2; |
---|---|---|---|---|
A thyroid disease | 0.257; 0.613 | 0.257; 0.613 | ‒; | 0.064; 0.801 |
Hor | 0.581; 0.446 | 0.581; 0.446 | ‒; | 6.997; 0.008 |
Est | 0.300; 0.584 | 0.300; 0.584 | ‒; | 0.074; 0.785 |
Prog | 0.038; 0.845 | 0.038; 0.845 | ‒; | 0.010; 0.922 |
An autoimmune disease | 0.078; 0.781 | 0.078; 0.781 | ‒; | 0.019; 0.890 |
PCOS | 0.242; 0.623 | 0.242; 0.623 | ‒; | 16.775; 0.000 |
BMI | 0.648; 0.421 | 0.648; 0.421 | ‒; | 0.161; 0.689 |