1. bookVolume 66 (2016): Edizione 1 (March 2016)
Dettagli della rivista
License
Formato
Rivista
eISSN
1846-9558
Prima pubblicazione
28 Feb 2007
Frequenza di pubblicazione
4 volte all'anno
Lingue
Inglese
Accesso libero

Synthesis and structure elucidation of some novel thiophene and benzothiophene derivatives as cytotoxic agents

Pubblicato online: 07 Mar 2016
Volume & Edizione: Volume 66 (2016) - Edizione 1 (March 2016)
Pagine: 53 - 68
Accettato: 25 Sep 2015
Dettagli della rivista
License
Formato
Rivista
eISSN
1846-9558
Prima pubblicazione
28 Feb 2007
Frequenza di pubblicazione
4 volte all'anno
Lingue
Inglese

1. F. M. Moghaddam, M. R. Khodabakhshi and A. Latifkar, A one-pot multicomponent synthesis of polysubstituted thiophenes via the reactions of an isocyanide, α-haloketones, and β-ketodithioesters in water, Tetrahedron Lett.55 (2014) 1251–1254; DOI: 10.1016/j.tetlet.2014.01.014.10.1016/j.tetlet.2014.01.014Search in Google Scholar

2. J. C. Lee, S. Kassis, S. Kumar, A. Badger and J. L. Adams, p38 Mitogen-activated protein kinase inhibitors-mechanisms and therapeutic potentials, Pharmacol. Ther.82 (1999) 389–397; DOI: 10.1016/S0163-7258(99)00008-X.10.1016/S0163-7258(99)00008-XSearch in Google Scholar

3. G. Zeni, C. W. Nogueira, D. O. Silva, P. H. Menezes, A. L. Braga, H. A. Stefani and J. B. T. Rocha, 2,5-Bis-(butyltelluro) thiophene as a convenient precursor for the synthesis of 2,5-bis-(acetylenic) thiophenes, Tetrahedron Lett.44 (2003) 685–688; DOI: 10.1016/S0040-4039(02)02659-X.10.1016/S0040-4039(02)02659-XSearch in Google Scholar

4. H. Z. Shams, M. H. Helal and F. A. Mohamed, A novel synthesis of polyfunctionally substituted pyrazolo [1,2-a]pyrazole, and thieno [3′,2′-3,4]pyrazolo [1,2-a]pyrazole systems, Phosphorus Sulfur Silicon174 (2001) 255–267; DOI: 10.1080/10426500108040250.10.1080/10426500108040250Search in Google Scholar

5. Y. M. Loksha, A. A. El-Barbary, M. A. El-Badawi, C. Nielsen and E. B. Pedersen, Synthesis of 2-(aminocarbonylmethylthio)-1H-imidazoles as novel capravirine analogues, Bioorg. Med. Chem.13 (2005) 4209–4220; DOI: 10.1016/j.bmc.2005.04.024.10.1016/j.bmc.2005.04.024Search in Google Scholar

6. J. M. Holmes, G. C. M. Lee, M. Wijono, R. Weinkam, L. A. Wheeler and M. E. Garst, Synthesis and carbonic anhydrase Inhibitory activity of 4-substituted 2-thiophenesulfonamides, J. Med. Chem.37 (1994) 1646–1651; DOI: 10.1021/jm00037a015.10.1021/jm00037a015Search in Google Scholar

7. T. J. Luker, H. G. Beaton, M. Whiting, A. Mete and D. R. Cheshire, Palladium catalysedamination of electron deficient halothiophenes, Tetrahedron Lett.41 (2000) 7731–7735; DOI: 10.1016/S0040-4039(00)01307-1.10.1016/S0040-4039(00)01307-1Search in Google Scholar

8. I. L. Pinto, R. L. Jarvest and H. T. Serafinowska, The synthesis of 5-alkoxy and 5-amino substituted thiophenes, Tetrahedron Lett.41 (2000) 1597–1600; DOI: 10.1016/S0040-4039(99)02338-2.10.1016/S0040-4039(99)02338-2Search in Google Scholar

9. A. Mishra, C.-Q. Ma and P. Bäuerle, Functional oligothiophenes: Molecular design for multidimensional nanoarchitectures and their applications, Chem. Rev.109 (2009) 1141–1276; DOI: 10.1021/cr8004229.10.1021/cr800422919209939Search in Google Scholar

10. H. E. Katz, Z. Bao and S. L. Gilat, Synthetic chemistry for ultrapure, processable and high-mobility organic transistor semiconductors, Acc. Chem. Res.34 (2001) 359–369; DOI: 10.1021/ar990114j.10.1021/ar990114j11352714Search in Google Scholar

11. T. Noda, I. Imae, N. Noma and Y. Shirota, 5,5″-bis{4-[bis(4-methylphenyl)amino]phenyl}2, 2′:5′,2″-terthiophene and 5,5″′-bis{4-[Bis(4-methylphenyl)amino]phenyl}2, 2′:5′, 2″:5″, 2″′-quaterthiophene as a novel family of amorphous molecular materials, Adv. Mater.9 (1997) 239–241; DOI: 10.1002/adma.19970090311.10.1002/adma.19970090311Search in Google Scholar

12. S. Kim, N. Dahal and T. Kesharwani, Environmentally benign process for the synthesis of 2,3-disubstituted benzo[b]thiophenes using electrophilic cyclization, Tetrahedron Lett.54 (2013) 4373–4376; DOI: 10.1016/j.tetlet.2013.05.139.10.1016/j.tetlet.2013.05.139Search in Google Scholar

13. S.-J. Jeong, R. Higuchi, T. Miyamoto, M. Ono, M. Kuwano and S. F. Mawatari, Bryoanthrathiophene, a new antiangiogenic constituent from the bryozoan watersipora subtorquata (d’Orbigny, 1852), J. Nat. Prod.65 (2002) 1344–1345; DOI: 10.1021/np010577+.10.1021/np010577+Search in Google Scholar

14. M. R. Bleavins, F. A. de la Iglesia, J. A. McCay, K. L. White, Jr., and A. E. Munson, Immunotoxico-logic studies with CI-959, a novel benzothiophene cell activation inhibitor, Toxicology98 (1995) 111–123; DOI: 10.1016/0300-483X(94)02985-4.10.1016/0300-483X(94)02985-4Search in Google Scholar

15. H. Z. Shams, R. M. Mohareb, M. H. Helal and A. E. Mahmoud, Synthesis, structure elucidation, and biological evaluation of some fused and/or pendant thiophene, pyrazole, imidazole, thiazole, triazole, triazine, and coumarin systems based on cyanoacetic 2-[(benzoylamino)thioxomethyl] hydrazide, Phosphorus Sulfur Silicon182 (2007) 237–263; DOI: 10.1080/10426500600892776.10.1080/10426500600892776Search in Google Scholar

16. L. Berrade, B. Aisa, M. J. Ramirez, S. Galiano, S. Guccione, L. R. Moltzau, F. O. Levy, F. Nicoletti, G. Battaglia, G. Molinaro, I. Aldana, A., Monge and S. Perez-Silanes, Novel benzo[b]thiophene derivatives as new potential antidepressants with rapid onset of action, J. Med. Chem.54 (2011) 3086–3090; DOI: 10.1021/jm2000773.10.1021/jm200077321469694Search in Google Scholar

17. H. U. Bryant and W. H. Dere, Selective estrogen receptor modulators: an alternative to hormone replacement therapy, Proc. Soc. Exp. Biol. Med.217 (1998) 45–52; DOI: 10.3181/00379727-217-44204.10.3181/00379727-217-442049421206Search in Google Scholar

18. R. Romagnoli, P. G. Baraldi, M. D. Carrion, C. L. Cara, D. Preti, F. Fruttarolo, M. G. Pavani, M. A. Tabrizi, M. Tolomeo, S. Grimaudo, A. Di Cristina, J. Balzarini, J. A. Hadfield, A. Brancale and E. Hamel, Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization, J. Med. Chem.50 (2007) 2273–2277; DOI: 10.1021/jm070050f.10.1021/jm070050f17419607Search in Google Scholar

19. Z.-F. Tao, L. A. Hasvold, J. D. Leverson, E. K. Han, R. Guan, E. F. Johnson, V. S. Stoll, K. D. Stewart, G. Stamper, N. Soni, J. J. Bouska, Y. Luo, T. J. Sowin, N.-H. Lin, V. S. Giranda, S. H. Rosenberg and T. D. Penning, Discovery of 3H-benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as potent highly selective and orally bioavailable inhibitors of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM) kinases, J. Med. Chem.52 (2009) 6621–6636; DOI: 10.1021/jm900943h.10.1021/jm900943h19842661Search in Google Scholar

20. Y. Loidreau, E. Deau, P. Marchand, M.-R. Nourrisson, C. Logé, G. Coadou, N. Loaëc, L. Meijer and T. Besson, Synthesis and molecular modelling studies of 8-arylpyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4-amines as multitarget Ser/Thr kinases inhibitors, Eur. J. Med. Chem.92 (2015) 124–134; DOI: 10.1016/j.ejmech.2014.12.038.10.1016/j.ejmech.2014.12.03825549552Search in Google Scholar

21. R. M. Mohareb, A. E. Mahmoud and M. A. Abdelaziz, New approaches for the synthesis of pyrazole, thiophene, thieno[2,3-b]pyridine, and thiazole derivatives together with their anti-tumor evaluations, Med. Chem. Res.23 (2014) 564–579; DOI: 10.1007/s00044-013-0664-7.10.1007/s00044-013-0664-7Search in Google Scholar

22. A. Martorana, C. Gentile, U. Perricone, A. P. Piccionello, R. Bartolotta, A. Terenzi, A. Pace, F. Mingoia, A. M. Almerico and A. Lauria, Synthesis, antiproliferative activity, and in silico insights of new 3-benzoylamino-benzo[b]thiophene derivatives, Eur. J. Med. Chem.90 (2015) 537–546; DOI:10.1016/j.ejmech.2014.12.002.10.1016/j.ejmech.2014.12.00225486425Search in Google Scholar

23. R. M. Mohareb, H. Z. Shams and S. I. Aziz, Novel synthesis of 4-(coumarin-3-yl)-1,3-thiazole, 2-(cou-marin-3-carbonyl)thieno(2,3-b)pyridine and 2-(coumarin-3-carbonyl)thiophene derivatives, Sulfur Lett.13 (1991) 101–110; DOI: 10.1002/chin.199238159.10.1002/chin.199238159Search in Google Scholar

24. R. M. Mohareb, S. I. Aziz, N. I. A. Sayed and H. Z. Shams, Reactions of benzoyl isothiocyanate with active methylene reagents: A novel synthesis of thiophene, thiazoline and thieno [2,3-d]pyrimidine derivatives, J. Chin. Chem. Soc.39 (1992) 181–187; DOI: 10.1002/jccs.199200030.10.1002/jccs.199200030Search in Google Scholar

25. R. M. Mohareb, H. Z. Shams and Y. M. Elkholy, The use of 4-phenyl-3-thiosemicarbazide in hetero-cyclic synthesis: novel synthesis of thiazole, pyrazole and 1,3,4-thiadiazine derivatives, Phosphorus Sulfur Silicon72 (1992) 93–102; DOI: 10.1002/chin.199319192.10.1002/chin.199319192Search in Google Scholar

26. H. Z. Shams Y. M. Elkholy, N. S. Ibrahim and M. H. Elnagdi, Nitriles in organic synthesis: new routes for synthesis of pyridines and azinothiopyrans, J. Prakt. Chem.330 (1988) 817–819; DOI: 10.1002/prac.19883300521.10.1002/prac.19883300521Search in Google Scholar

27. H. Z. Shams, R. M. Mohareb, M. H. Helal and A. E. Mahmoud, Novel synthesis and antitumor evaluation of polyfunctionally substituted heterocyclic compounds derived from 2-cyano-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-acetamide, Molecules16 (2011) 52–73; DOI: 10.3390/molecules16010052.10.3390/molecules16010052625915221187817Search in Google Scholar

28. A. Monks, D. Scudiero, P. Skehan, R. Shoemaker, K. Paull, D. Vistica, C. Hose, J. Langley, P. Cronise, A. Vaigro-Wolff, M. Gray-Goodrich, H. Campbell, J. Mayo and M. Boyd, Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines, J. Natl. Cancer Inst.83 (1991) 757–766; DOI: 10.1093/jnci/83.11.757.10.1093/jnci/83.11.7572041050Search in Google Scholar

29. K. D. Paull, R. H. Shoemaker, L. Hodes, A. Monks, D. A. Scudiero, L. Rubinstein, J. Plowman and M. R. Boyd, Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and compare algorithm, J. Natl. Cancer Inst.81 (1989) 1088–1092; DOI: 10.1093/jnci/81.14.1088.10.1093/jnci/81.14.10882738938Search in Google Scholar

30. L. H. Li and F. L. Yu, Transcriptional specificities of adriamycin, Biochem. Mol. Biol. Int.31 (1993) 879–887.Search in Google Scholar

Articoli consigliati da Trend MD

Pianifica la tua conferenza remota con Sciendo