Parameter | Euthyroid with LNT (TSH 0.5–2.5) (n = 118) | Euthyroid with HNT (TSH > 2.5) (n = 48) | |
---|---|---|---|
Age† (years) | 30 (52) | 33 (52) | 0.373 |
BMI‡ | 26.99 [4.96] | 27.23[5.12] | 0.782 |
Waist circumference‡ | 84.13 [±11.92] | 84.69 [±10.76] | 0.812 |
Biochemical data | |||
TSH (mIU/L)† | 1.6 (2.17) | 3.15 (1.7) | |
FT4 (ng/dl)† | 1.24 (1.22) | 1.21 (0.64) | |
FT3 (pg/ml)‡ | 3.48 [±0.39] | 3.26 [±0.39] | |
TPO-Ab titer (IU/ml)† | 5.81 (265.6) | 10.23 (504.6) | |
Prolactin (ng/ml)† | |||
TPO positivity | 14.8 (48.43) | 15.54 (35.77) | 0.986 |
Hyperprolactinemia | 9 (7.6%) | 8 (17.4%) | |
37 (31.4%) | 9 (20.5%) | 0.365 | |
Zulewski score† | 2 (7) | 2 (7) | 0.149 |
Correlations | Age (years) | TSH level (mIU/L) | FT4 level (ng/dl) | Median TPO-Ab titer (IU/ml) | Zulewski’ score |
---|---|---|---|---|---|
Age (years) | 0.027 | –0.240** | 0.126 | 0.158* | |
TSH level (mIU/L) | 0.027 | –0.275** | 0.319** | 0.287** | |
FT4 level (ng/dl) | –0.240** | –0.275** | –0.203** | –0.149* | |
Median TPO-Ab titer (IU/ml) | 0.126 | 0.319** | –0.203** | 0.200** |
Parameter | Frequencies, n (%) |
---|---|
Age (years)† | 31.5 (52) |
Age range (years) | 18–70 |
Sex | |
Female | 188 (80.69) |
Male | 45 (19.31) |
Body mass index‡ | 27.28 [4.84] |
Waist circumference (cm)‡ | 84.88 [12.14] |
Smoker (yes%) | 20 (8.6) |
Education | |
Educated | 155 (90.1) |
Illiterate | 17 (9.9) |
Work | |
Student | 34 (14.8) |
No work | 67 (29.1) |
Employee | 85 (37) |
Free work | 44 (19.2) |
Marital status | |
Married | 138 (60) |
Single | 88 (38.3) |
Divorced | 4 (1.7) |
Exercise | |
Rarely | 99 (44.4) |
Some time | 82 (36.8) |
Daily | 42 (18.8) |
Parameters | SCH (n = 67), mean (±SD) | Euthyroid (n = 166), mean (±SD) | |
---|---|---|---|
Age (years)† | 34 (52) | 31 (53) | 0.368 |
Sex (female) | 85.1% | 78.9% | 0.281 |
Marital status (married) | 68.3% | 56.9% | 0.289 |
BMI (kg/m2)‡ | 27.95 [4.35] | 27.00 [5.01] | 0.183 |
Waist circumference (cm)‡ | 86.77 [13.19] | 84.12 [11.66] | 0.202 |
Biochemical data | |||
TSH (mIU/L)† | 5.89 (6.54) | 1.95 (4.09) | |
FT4 (ng/dl)† | 1.15 (11.35) | 1.23 (1.22) | |
FT3 (pg/ml)‡ | 3.39[±0.46] | 3.43[±0.39] | 0.733 |
TPO-Ab titer (IU/ml)† | 15.22 (606) | 6.64 (504.6) | |
Prolactin (ng/ml)† | 17.29 (45.13) | 15.01 (48.43) | 0.283 |
TPO positivity | 43.8% | 10.2% | |
Hyperprolactinemia | 27% | 28% | 0.873 |
Zulewski score† | 3 (5) | 2 (6) | |
Clinical data | |||
Goiter | 15.1% | 4.9% | |
Menstrual disturbance | 51.2% | 39.7% | 0.193 |
Decreased appetite | 29.8% | 19.9% | 0.126 |
Fatigue | 80.3% | 58.2% | |
Muscle pain | 62.3% | 38.9% | |
Memory loss | 50.8% | 43% | 0.304 |
Alopecia | 46.6% | 40.4% | 0.42 |
Hirsutism | 24.5% | 22.1% | 0.723 |
Cold intolerance | 37.3% | 23.8% | |
Galactorrhea | 3.6% | 1.9% | 0.473 |