Comparative Clinical and Haematological Investigations in Lactating Cows with Subclinical and Clinical Ketosis

1. Bell, A.W. (1995). Regulation of organic nutrient metabolism during transition from late pregnancy to early lactation. J. Anim. Sci. 73, 2804-2819. PMid:858287210.2527/1995.7392804xSearch in Google Scholar

2. Oetzel, G.R. (2004). Monitoring and testing dairy herds for metabolic disease. Vet. Clin. North Am. Food Anim. Pract. 20, 651-674. http://dx.doi.org/10.1016/j.cvfa.2004.06.006 PMid:1547162910.1016/j.cvfa.2004.06.006Search in Google Scholar

3. Kirovski, D., Šamanc, H., Cernescu, H., Jovanović, M., Vujanac, I. (2008). Fatty liver incidence on dairy cow farms in Serbia and Romania. International Symposium New Researches in Biotechnology”, Romania, Buchurest, November 20th to 21st, Biotechnology, series F, special volume. Search in Google Scholar

4. Radostis, O.M., Gay, C.C., Blood, D.C., Hinchcliff, K.W. (2000). Ketosis of ruminants. In: Radostits OM, DC Blood and CC Gay (Eds). Veterinary medicine: A textbook of the diseases of cattle, sheep, pigs, goats and horses. (pp. 1452-1462). 9th Edition. London: Sounders Company.Search in Google Scholar

5. Nogalski, Z., Górak, E. (2008). Effects of the body condition of heifers at calving and at the first stage of lactation on milk performance. Med. Weter. 64, 322-326.Search in Google Scholar

6. Duffield, T.F., Kelton, D.F., Leslie, K.E., Lissemore, K.D., Lumsden, J.H. (1997). Use of test day milk fat and milk protein to detect subclinical ketosis in dairy cattle in Ontario. Can. Vet. J. 38, 713-718. PMid:9360791 PMCid:PMC1576823Search in Google Scholar

7. McArt, J.A., Nydam, D.V., Oetzel, G.R. (2013). Dry period and parturient predictors of early lactation hyperketonemia in dairy cattle. J. Dairy Sci. 96, 198-209. http://dx.doi.org/10.3168/jds.2012-5681 PMid:2310296110.3168/jds.2012-5681Search in Google Scholar

8. Whitaker, D.A., Smith, E.J., da Rosa, G.O., Kelly, J.M. (1993). Some effects of nutrition and management on the fertility of dairy cattle. Vet. Rec. 133, 61-64. http://dx.doi.org/10.1136/vr.133.3.61 PMid:821248410.1136/vr.133.3.61Search in Google Scholar

9. Walsh, R., LeBlanc, S., Duffield, T., Leslie, K. (2004). Retrospective analysis of the association between subclinical ketosis and conception failure in Ontario dairy herds. Proc. World Buiatrics Congress / Med. Vet. Quebec, 34-152.Search in Google Scholar

10. Suriyasathaporn, W., Heuer, C., Noordhuizen-Stassen, E.N., Schukken, Y.H. (2000). Hyperketonemia and udder defense: a review. Vet. Res. 31, 397-412. http://dx.doi.org/10.1051/vetres:2000128 PMid:1095824110.1051/vetres:2000128Search in Google Scholar

11. LeBlanc, S.J., Leslie, K.E., Duffield, T.F. (2005). Metabolic predictors of displaced abomasum in dairy cattle. J. Dairy Sci. 88, 159-170. http://dx.doi.org/10.3168/jds.S0022-0302(05)72674-610.3168/jds.S0022-0302(05)72674-6Search in Google Scholar

12. Duffield, T.F., Lissemore, K.D., McBride, B.W., Leslie, K.E. (2009). Impact of hyperketonemia in early lactation dairy cows on health and production. J. Dairy Sci. 92, 571-580. http://dx.doi.org/10.3168/jds.2008-1507 PMid:1916466710.3168/jds.2008-1507Search in Google Scholar

13. Meglia, G.E., Johannisson, A., Petersson, L., Persson Waller, K. (2001). Changes in some blood micronutritiens, leukocytes and neutrophil expression of adhesion molecules in periparturient dairy cows. Acta Vet. Scand. 42, 139-150. http://dx.doi.org/10.1186/1751-0147-42-139 PMid:11455894 PMCid:PMC220234210.1186/1751-0147-42-139Search in Google Scholar

14. Ospina, P.A., Nydam, D.V., Stokol, T., Overton, T.R. (2010). Associations of elevated non-esterified fatty acids and β-hydroxybutyrate concentrations with early lactation reproductive performance and milk production in transition dairy cattle in the northeastern United States. J. Dairy Sci. 93, 1596-1603. http://dx.doi.org/10.3168/jds.2009-2852 PMid:2033843710.3168/jds.2009-2852Search in Google Scholar

15. Hungerford, T.G. (1990). Diseases of cattle. In: Diseases of livestock, 9th Edition (pp. 34-347).Search in Google Scholar

16. Oetzel, G.R. (2007). Herd-level ketosis - diagnosis and risk factors. Preconference seminar 7C: Dairy herd problem investigation strategies: transition cow troubleshooting American association of bovine practitioners, 40th Annual Conference, September 19, 2007 - Vancouver, BC, CanadaSearch in Google Scholar

17. Waltner, S.S., McNamara, J.P., Hillers, J.K. (1993). Relationships of body condition score to production variables in high producing Holstein cows. J. Dairy Sci. 76, 3410-3419. http://dx.doi.org/10.3168/jds.S0022-0302(93)77679-110.3168/jds.S0022-0302(93)77679-1Search in Google Scholar

18. Bewley, J.M., Schutz, M.M. (2008). Review: An interdisciplinary review of body condition scoring for dairy cattle. Professional Animal Scientist 24, 507-529.10.15232/S1080-7446(15)30901-3Search in Google Scholar

19. Garnsworthy, P. (2008). Influences of body condition on fertility and milk yield. In: Proc dairy cattle reproduction council convention, 63-72.Search in Google Scholar

20. Skidmore, A.L., Peeters, K.A.M., Sniffen, C.J., Brand, A. (2001). Monitoring dry period management. In: Brand, A., Noordhuizen, J. P. T. M., Schukken, Y. H. (Eds.), Herd Health and Production Management in Dairy Practice. (pp. 171-201). Wageningen PressSearch in Google Scholar

21. Gillund, P., Reksen, O., Grohn, Y.T., Karlberg, K. (2001). Body condition related to ketosis and reproductive performance in Norwegian dairy cows. J. Dairy Sci. 84, 1390-1396. http://dx.doi.org/10.3168/jds.S0022-0302(01)70170-110.3168/jds.S0022-0302(01)70170-1Search in Google Scholar

22. Găvan, C., Retea, C., Motorga, V. (2010). Changes in the hematological profile of Holstein primiparous in periparturient period and in early to mid-lactation. Animal Sciences and Biotechnologies 43, 244-246.Search in Google Scholar

23. Duffield, T.F. (2004). Monitoring strategies for metabolic disease in transition dairy cows. IVIS, 23rd WBC Congress, Québec, Canada.Search in Google Scholar

24. Goldhawk, C., Chapinal, N., Veira, D.M., Weary, D.M., Keyserlingk, von M.A.G. (2009). Prepartum feeding behavior is an early indicator of subclinical ketosis. J. Dairy Sci. 92, 4971-4977. http://dx.doi.org/10.3168/jds.2009-2242 PMid:19762814 10.3168/jds.2009-2242Search in Google Scholar

25. Kinoshita, A., Wolf, C., Zeyner, A. (2010). Studies on the incidence of hyperketonemia with and without hyperbilirubinaemia in cows in Mecklenburg- Vorpommern (in Germany) in the course of the year. Tieraerztliche Praxis 38, 7-15.Search in Google Scholar

26. Seifi, H.A., LeBlanc, S.J., Leslie, K.E., Duffield, T.F. (2011). Metabolic predictors of post-partum disease and culling risk in dairy cattle. Vet. J. 188, 216-220. http://dx.doi.org/10.1016/j.tvjl.2010.04.007 PMid:2045753210.1016/j.tvjl.2010.04.007Search in Google Scholar

27. Geishauser, T., Leslie, K., Tenhag, J., Bashiri, A. (2000). Evaluation of eight cowside ketone tests in milk for detection of subclinical ketosis in dairy cows. J. Dairy Sci. 83, 296-299.10.3168/jds.S0022-0302(00)74877-6Search in Google Scholar

28. Binev, R., Marutsova, V., Radev, V. (2014). Clinical and haematological studies on subclinical lactational ketosis in dairy goats. Agricultural Science and Technology 6, 427−430.Search in Google Scholar

29. Andrews, A.H., Blowey, R.W., Boyd, H., Eddy, R.G. (2004). Bovine Medicine Diseases and Husbandry of Cattle. Second edition. USA: Blackwell Publishing Company.Search in Google Scholar

30. González, F.D., Mui-o, R., Pereira, V., Campos, R., Benedito, J.L. (2011). Relationship among blood indicators of lipomobilization and hepatic function during early lactation in high-yielding dairy cows. J. Dairy Sci. 12, 251-255. http://dx.doi.org/10.4142/jvs.2011.12.3.25110.4142/jvs.2011.12.3.251Search in Google Scholar

31. Suthar, V.S., Canelas-Raposo, J., Deniz, A., Heuwieser, W. (2013). Prevalence of subclinical ketosis and relationships with postpartum diseases in European dairy cows. J. Dairy Sci. 96, 2925-2938. http://dx.doi.org/10.3168/jds.2012-6035 PMid:2349799710.3168/jds.2012-6035Search in Google Scholar

32. Edmonson, A.J., Lean, I.J., Weaver, L.D., Farver, T., Webster, G. (1989). A body condition chart for Holstein dairy cows. J. Dairy Sci. 72, 68-78. http://dx.doi.org/10.3168/jds.S0022-0302(89)79081-010.3168/jds.S0022-0302(89)79081-0Search in Google Scholar

33. LeBlanc, S. (2010). Monitoring metabolic health of dairy cattle in the transition period. J. Reprod. Dev. 56, 29-35. http://dx.doi.org/10.1262/jrd.1056S2910.1262/jrd.1056S29Search in Google Scholar

34. Grummer, R.R. (1993). Etiology of lipid-related metabolic disorders in periparturient dairy cows. J. Dairy Sci. 76, 3882-3896. http://dx.doi.org/10.3168/jds.S0022-0302(93)77729-210.3168/jds.S0022-0302(93)77729-2Search in Google Scholar

35. López-Gatius, F., Santolaria, P., Yaniz, J., Rutllant, J., López-Béjar, M. (2002). Factors affecting pregnancy loss from gestation day 38 to 90 in lactating dairy cows from a single herd. Theriogenology 57, 1251-1261. http://dx.doi.org/10.1016/S0093-691X(01)00715-410.1016/S0093-691X(01)00715-4Search in Google Scholar

36. Ruegg, P.L., Milton, R.L. (1995). Body condition scores of Holstein cows on Prince Edward Island, Canada: relationship with yield, reproductive performance, and disease. J. Dairy Sci. 78, 552-564. http://dx.doi.org/10.3168/jds.S0022-0302(95)76666-810.3168/jds.S0022-0302(95)76666-8Search in Google Scholar

37. Markusfeld, O., Galon, N., Ezra, E. (1997). Body condition score, health, yield and fertility in dairy cows. Vet. Rec. 141, 67-72. http://dx.doi.org/10.1136/vr.141.3.67 PMid:925743510.1136/vr.141.3.67Search in Google Scholar

38. Sahinduran, S., Sezer K., Buyukoglu T., Albay M.K., Karakurum M.C. (2010). Evaluation of some haematological and biochemical parameters before and after treatment in cows with ketosis and comparison of different treatment methods. J. Anim. Vet. Adv. 9, 266-271. http://dx.doi.org/10.3923/javaa.2010.266.27110.3923/javaa.2010.266.271Search in Google Scholar

39. Belić, B., Cincović, M.R., Stojanović, D., Kovačević, Z., Vidović, B. (2010). Morphology of erythrocyte and ketosis in dairy cows with different body condition. Contemporary agriculture 59, 306-311.Search in Google Scholar

40. Sandev, N., Ilieva, D., Sizov, I., Rusenova, N., Iliev, E. (2006). Prevalence of enzootic bovine leukosis in the Republic of Bulgaria in 1997-2004. Vet. Arhiv 76, 263-268.Search in Google Scholar

41. Hoeben, D., Heyneman, R., Burvenich, C. (1997). Elevated levels of beta-hydroxybutyric acid in periparturient cows and in vitro effect on respiratory burst activity of bovine neutrophils. Vet. Immunol. Immunopathol. 58, 165-170. http://dx.doi.org/10.1016/S0165-2427(97)00031-710.1016/S0165-2427(97)00031-7Search in Google Scholar

42. Hoeben, D., Burvenich, C., Massart-Leen, A.M., Lenjou, M., Nijs, G., Van Bockstaele, D. (1999). In vitro effect of ketone bodies, glucocorticosteroids and bovine pregnancy-associated glycoprotein on cultures of bone marrow progenitor cells of cows and calves. Vet. Immunol. Immunopathol. 68, 229-240. http://dx.doi.org/10.1016/S0165-2427(99)00031-810.1016/S0165-2427(99)00031-8Search in Google Scholar

43. Suriyasathaporn, W., Daemen, A.J., Noordhuizen- Stassen, E.N., Dieleman, S.J., Nielen, M., Schukken, Y.H. (1999). Beta-hydroxybutyrate levels in peripheral blood and ketone bodies supplemented in culture media affect the in vitro chemotaxis of bovine leukocytes. Vet.Immunol. Immunopathol. 68, 177-186. http://dx.doi.org/10.1016/S0165-2427(99)00017-310.1016/S0165-2427(99)00017-3Search in Google Scholar

44. Cincović, R.M., Belić, B., Radojičić, B., Hristov, S., Đoković, R. (2012). Infl uence of lipolysis and ketogenesis to metabolic and hematological parameters in dairy cows during periparturient period. Acta Vet. 62, 429-444. http://dx.doi.org/10.2298/AVB1204429C 10.2298/AVB1204429CSearch in Google Scholar

45. Belić, B., Cincović, M. R., Krčmar, Lj., Vidović, B. (2011). Reference values and frequency distribution of hematological parameters in cows during lactation and in pregnancy. Contemporary agriculture 60, 145-151.Search in Google Scholar

46. Burton, J.L., Madsen, S.A., Chang, L.C., Weber, P.S., Buckham, K.R, Van Dorp, R., Hickey, M.C., Earley, B. (2005). Gene expression signatures in neutrophils exposed to glucocorticoids: A new paradigm to help explain “neutrophil dysfunction” in parturient dairy cows. Vet. Immunol. Immunopathol. 105, 197-219. http://dx.doi.org/10.1016/j.vetimm.2005.02.012 PMid:15808301 10.1016/j.vetimm.2005.02.01215808301Search in Google Scholar

47. Hefnawy, A.E., Shousha, S., Youssef, S. (2011). Hematobiochemical profile of pregnant and experimentally pregnancy toxemic goats. J. Basic. Appl. Chem. 1, 65-69.Search in Google Scholar

48. Wyle, F.A., Kent, J.R. (1977). Immunosuppression by sex steroid hormones. Clin. Exp. Immunol. 27, 407. PMid:862230 PMCid:PMC1540928Search in Google Scholar