<abstract xmlns="http://www.w3.org/1999/xhtml">

<bold>Introduction:</bold> Severe ischemia occurring in the lower limbs represents the advanced stage of peripheral artery disease (PAD). Atherosclerosis and inflammatory markers have been intensively studied to identify prognostic tools with a role in the evolution of patients with PAD. The aim of this study is to demonstrate the predictive value of systemic inflammatory markers such as the neutrophil-to-lymphocyte ratio (NLR) and the systemic inflammation index (SII) in the prognosis of patients diagnosed with critical leg ischemia (CLI) undergoing infrainguinal surgical revascularization with remote endarterectomy.
<bold>Materials and methods:</bold> This retrospective study included all patients admitted to the Vascular Surgery Clinic of the County Emergency Clinical Hospital of Târgu Mureș, Romania between January 2018 and December 2021, who had critical limb ischemia Leriche-Fontaine stage III and were treated with endarterectomy. Patients were divided into two groups based on the presence or absence of patency in the lower limbs at 12 months.
<bold>Results:</bold> There was a higher baseline value of neutrophil count (p &lt;0.0001), platelet count (p = 0.006), NLR and SII value (p &lt;0.0001), as well as a lower value of lymphocyte count (p = 0.001) in the group without patency at 12 months. The ROC curve analysis showed that the NLR and SII were associated with the risk of major amputation and primary patency failure at 12 months, while multivariate analysis has shown that arterial hypertension (OR 3.63, p = 0.04), history of myocardial infarction (OR 2.93, p = 0.009), diabetes mellitus (OR 2.20; p = 0.04) and smoking (OR 3.48, p &lt;0.0001) were also predictors of primary patency failure.
<bold>Conclusions:</bold> The results of this study demonstrated the predictive role of NLR and SII regarding poor outcomes among patients with CLI Leriche-Fontaine stage III undergoing infrainguinal surgical revascularization with remote endarterectomy.
</abstract>

“George Emil Palade” University of Medicine, Pharmacy, Science and Technology

Neutrophil-to-Lymphocyte Ratio and Systemic Inflammation Index as Predictors of Poor Outcome in Patients with Critical Limb Ischemia Treated with Remote Endarterectomy

Department of Cardiology and Vascular Medicine

Faculty of Medicine Universitas Indonesia

Focal Atrial Tachycardia as Presenting Feature of Left Atrial Myxoma

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<bold>Introduction:</bold> In acute heart failure patients, the prothrombotic state is likely due to arterial and venous endothelial dysfunction. Decompensated heart failure appears to also be associated with increased levels of prothrombotic molecules, such as fibrinogen and von Willebrand factor, which also contribute to the prothrombotic state.
<bold>Case presentation:</bold> We present the case of a 72-year-old male patient, admitted for signs of acute heart failure with bilateral ankle edema. Laboratory data showed D-dimer level >5 µg/mL, which raised the suspicion of pulmonary embolism secondary to deep vein thrombosis. Doppler ultrasound performed to exclude a deep vein thrombosis revealed a total occlusion of the superficial femoral artery on the lower left limb and an abdominal aorta with a lumen diameter of 35 mm and a true lumen of 18.6 mm with circular isoechoic material on the aortic wall. The computed tomography angiography described an aneurysm of the abdominal aorta with mural thrombosis extending to the bifurcation level.
<bold>Conclusion:</bold> In patients with acute heart failure, a comprehensive vascular assessment is also needed. The therapeutic management of these patients varies from conservative to endovascular or surgical therapy, but revascularization therapy should be considered based on the patient’s medical condition.
</abstract>

Arterial Embolic Complications in a Patient with Acute Heart Failure

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<bold>Background:</bold> Hypertension is a crucial general health issue. Severe and acute hypertension needs urgent medical intervention. Self-care behaviors can help patients with hypertension in controlling blood pressure and preventing hypertensive emergencies. This study aimed to determine the perception of hypertension towards self-care behaviors using constructs of the theory of planned behavior (TPB) in critically ill patients with hypertension to prevent hypertensive emergencies.
<bold>Material and Methods:</bold> This study was conducted based on the directed qualitative content analysis of 33 critically ill patients with hypertension who participated in semi-structured interviews and focus group discussions. Results: The data were analyzed based on the four main categories of TPB. The attitude category consisted of positive and negative subcategories. The subjective norms category consisted of authority of healthcare staff, family support and approval, and influence of friends subcategories. The perceived behavioral control category included discipline, self-control, receiving consultation, individual concerns, financial problems, access to medicine, food culture, and coronavirus limitations subcategories. The behavioral intention category had intention to perform the behavior and intention to continue a behavior subcategories.
<bold>Conclusion:</bold> The results revealed the requirement for a multidimensional approach to improve attitude, subjective norms, and behavioral control for performing self-care behaviors to reduce the number of hypertensive emergencies in critically ill patients with hypertension. Factors affecting self-care included socioeconomic status, family support, governmental organizations, and participants’ health condition.
</abstract>

Social Determinants in Health Promotion Research Center, Hormozgan Health Institute, Faculty of Health

Self-Care Behaviors in Patients with Hypertension to Prevent Hypertensive Emergencies: a Qualitative Study Based on the Theory of Planned Behavior

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Journal of Cardiovascular Emergencies

 The Journal of Cardiovascular Emergencies aims to publish top quality papers related to acute conditions in any cardiovascular pathology. The journal will mainly focus on recent advances in the field of diagnosis and treatment of the most common causes of cardiovascular emergencies, including acute coronary syndromes, acute heart failure, acute aortic diseases, pulmonary embolism, peripheral arterial diseases or cardiac arrhythmia. Interdisciplinary approaches will be extremely welcomed, presenting new advances in the approach of different other pathologies (i.e. stroke) from the cardiovascular perspective.  The Journal of Cardiovascular Emergencies will publish high-quality basic and clinical research related to these topics, in a common approach that will integrate the clinical studies with the pre-clinical work dedicated to discovery of new mechanisms involved in the development and progression of acute cardiovascular conditions.  Especially in the case of acute coronary syndromes, the journal will try to provide the entire cardiology community with the perspective of the regional cardiology networks in Central and Eastern European countries, reflecting the regional model of care in cardiovascular acute conditions.  The journal will primarily focus on publishing original research papers, but also other types of materials (such as review articles, case reports, state of the art papers, comments to editor, etc) will be extremely welcomed.  Rejection Rate   30%   Archiving  Sciendo archives the contents of this journal in Portico - digital long-term preservation service of scholarly books, journals and collections.  Plagiarism Policy  The editorial board is participating in a growing community of Similarity Check System's users in order to ensure that the content published is original and trustworthy. Similarity Check is a medium that allows for comprehensive manuscripts screening, aimed to eliminate plagiarism and provide a high standard and quality peer-review process. 