<abstract xmlns="http://www.w3.org/1999/xhtml">

The study explore some of the factors showing the biocompatibility and cellular metabolism of stem cells from apical papilla after their treatment with hapten solutions of two intracanal medicaments - Hydrocal and Acroseal. The MTT test and Annexin V test are used and the levels of HMOX-1 and IDO monitored after 48 hours of incubation in hapten solutions. In addition to proliferation and apoptosis, the possible sensitizing potential of these dental materials is assessed. The results show that after 48 hours, the groups treated with dental haptens found significantly fewer living cells than in the control group, which is especially indicative in the case of Acroseal. The proliferative activity of stem cells is increased, but without significant differences. HMOX-1 was statistically elevated in the Acroseal-treated group, indicative of its sensitizing capacity. IDO is statistically elevated in the group of cells treated with Hydrocal, which unequivocally speaks of the serious oxidative stress up to 48 hours and the need for protective action of this enzyme.
</abstract>

Department of Imaging and Oral Diagnostics, Faculty of Dental Medicine

Department of Conservative Dentistry, Faculty of Dental Medicine

In vitro evaluation of biocompatibility of two intracanal medicaments on stem cells from apical papilla – a comparative study

<abstract xmlns="http://www.w3.org/1999/xhtml">

Coronary circulation determines the proper functioning of the heart muscle and blood circulation in the body. Cardiovascular diseases in humans are creating an ever-increasing demand for more research into their pathogenesis, diagnosis and treatment.
Animal models of organs are an indispensable part of research for the development of human medicine. Due to the high genetic similarity, the most commonly used donor is the domestic pig. The Eurasian wild boar is the ancestor of the domestic pig and an invasive species not covered by European protection programmes. Given its analogous structure and genotype to the pig, it could potentially also become an organ donor.
The aim of this study was to analyse the normal coronary anatomy of the Eurasian wild boar and compare it to humans, domestic pigs and other animal species.
The study was conducted on 60 wild boar hearts. Twenty-eight slides were prepared using acrylic, while liquid latex was injected into 32 hearts. The blood vessels were then manually prepared using surgical instruments for examination.
Both the right coronary artery and the left coronary artery of the boar diverge from the ascending aorta from opposite aortic sinuses. The left coronary artery begins its course in the left aortic sinus, starting between the left appendage and the pulmonary trunk. It then heads inferiorly. The right coronary artery supplies blood to the right atrium and right ventricle.
The study points to the wild boar coronary system’s individual morphological features and notes the common arterial patterns in mammals.
</abstract>

Anatomy of the coronary arteries in Eurasian wild boar (<italic>Sus scrofa</italic>)

<abstract xmlns="http://www.w3.org/1999/xhtml">

The flexor retinaculum is a structure located in the wrist, which spreads between the bones forming the carpal tunnel. Its task is to maintain the relative stabilization and protection of incorporated structures. It is also an attachment for the thenar muscles, causing biomechanical interactions in the wrist. Pathologies occurring in the carpal tunnel structures often cause pressure increase, leading to compression of the median nerve, causing carpal tunnel syndrome (CTS). This work aims to review literature knowledge and compile research outcomes in the PubMED and Google scholar databases.
The results indicate the variability in size and aspects of flexor retinaculum due to gender, and the relationship between gender and the incidence of CTS. The data also show the flexor retinaculum’s molecular variability and environmental factors’ potential impact on these changes. This article demonstrates how anatomical conditions and physical features influence CTS development.
</abstract>

Division of Anatomy, Department of Human Morphology and Embryology

Features of the flexor retinaculum and its individual variation in carpal tunnel syndrome predisposition - a systematic review

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Medical Journal of Cell Biology

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Medical Journal of Cell Biology

Volume 10 (2022): Issue 3 (September 2022)

In vitro evaluation of biocompatibility of two intracanal medicaments on stem cells from apical papilla – a comparative study

Anatomy of the coronary arteries in Eurasian wild boar (Sus scrofa)

Features of the flexor retinaculum and its individual variation in carpal tunnel syndrome predisposition - a systematic review

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