<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>This is the first Romanian investigation of oral candidosis in patients suffering of HIV-infection or type 1 <italic>diabetes mellitus</italic> (T1DM). <italic>Candida albicans</italic> was the dominant species in both types of isolates: n = 14 (46.7%) in T1DM, n = 60 (69.8%) in HIV. The most frequent non<italic>albicans Candida</italic> spp. were <italic>Candida kefyr</italic> (n = 6; 20%) in T1DM and <italic>Candida dubliniensis</italic> (n = 8; 9.3%) in HIV. Resistance to fluconazole was detected only in the HIV non<italic>-albicans Candida</italic> group (n = 8; 9.3%). All isolates were susceptible to VOR. The experimental drug MXP had MIC values equal or close to the ones of VOR. Echinocandin resistance was more frequent than azole resistance.</p>
</abstract>

This is the first Romanian investigation of oral candidosis in patients suffering of HIV-infection or type 1 diabetes mellitus (T1DM). Candida albicans was the dominant species in both types of isolates: n = 14 (46.7%) in T1DM, n = 60 (69.8%) in HIV. The most frequent nonalbicans Candida spp. were Candida kefyr (n = 6; 20%) in T1DM and Candida dubliniensis (n = 8; 9.3%) in HIV. Resistance to fluconazole was detected only in the HIV non-albicans Candida group (n = 8; 9.3%). All isolates were susceptible to VOR. The experimental drug MXP had MIC values equal or close to the ones of VOR. Echinocandin resistance was more frequent than azole resistance.

Etiologic Agents and Antifungal Susceptibility of Oral Candidosis from Romanian patients with HIV-infection or type 1 <italic>diabetes mellitus</italic>

Polish Journal of Microbiology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Etiologic Agents and Antifungal Susceptibility of Oral Candidosis from Romanian patients with HIV-infection or type 1 

This is the first Romanian investigation of oral candidosis in patients suffering of HIV-infection or type 1 diabetes mellitus (T1DM). Candida albicans was the...

Etiologic Agents and Antifungal Susceptibility of Oral Candidosis from Romanian patients with HIV-infection or type 1 diabetes mellitus

Publié en ligne: 15 mars 2016

Pages: 123 - 129

Reçu: 11 mars 2015

Accepté: 21 avr. 2015

DOI: https://doi.org/10.5604/17331331.1197327

Mots clés
antifungal susceptibility, MXP-4509, oral candidosis, Romanian HIV and diabetes patients

© 2016 BOGDAN MINEA et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Etiologic Agents and Antifungal Susceptibility of Oral Candidosis from Romanian patients with HIV-infection or type 1 diabetes mellitus

Publié en ligne: 15 mars 2016

Pages: 123 - 129

Reçu: 11 mars 2015

Accepté: 21 avr. 2015

DOI: https://doi.org/10.5604/17331331.1197327

Mots clésantifungal susceptibility, MXP-4509, oral candidosis, Romanian HIV and diabetes patients

© 2016 BOGDAN MINEA et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Mots clés
antifungal susceptibility, MXP-4509, oral candidosis, Romanian HIV and diabetes patients