Coronary artery events in Thai patients with psoriasis using Framingham and Ramathibodi–Electricity Generating Authority of Thailand risk scores
Article Category: Brief communication (Original)
Publié en ligne: 31 janv. 2017
Pages: 495 - 500
DOI: https://doi.org/10.5372/1905-7415.0904.419
Mots clés
© 2015 Sakunee Khankham, Leena Chularojanamontri, Chanisada Wongpraparut, Narumol Silpa-archa, Nuttaporn Janyong, Prin Vathesatogkit
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Background
soriasis is an independent risk factor for cardiovascular disease. Several tools such as Framingham score (FRS) and Ramathibodi-Electricity Generating Authority of Thailand (RAMA-EGAT) score have been developed to predict the 10-year risk of coronary artery disease (CAD) and death. However, there are only few studies determine CAD risk using FRS and RAMA-EGAT score in Asian patients with psoriasis.
Objectives
To investigate the risk of CAD events using the FRS and RAMA-EGAT score in Thai patients with psoriasis.
Methods
Predictive factors that associated with intermediate and high risk (≥10%) of CAD events within 10-year were determined. Variables, including age, sex, blood pressure, cholesterol, high-density lipoprotein, diabetes mellitus, waist circumference, smoking, and alcohol intake were used to calculate scores.
Results
Of 145 patients with psoriasis and a mean age of 48.1 ± 14.1 years, 72 patients were men. Using FRS and RAMA-EGAT, 25% and 13% of the patients, respectively had a ≥10% risk of developing CAD events. A higher risk of CAD was predicted when severe psoriasis was considered. The duration of disease and treatment were associated with an increased risk of CAD using the FRS and RAMA-EGAT score by multivariate analysis.
Conclusions
A substantial portion of our patients had a CAD risk ≥10%, with significant relationship with duration of disease and treatment. Early screening of CAD and appropriate treatments of psoriasis may be helpful for preventing CAD in patients with psoriasis.