[1. Feldmann RE Jr, Bieback K, Maurer MH, Kalenka A, Burgers HF, Gross B, et al. Stem cell proteomes: a profile of human mesenchymal stem cells derived from umbilical cord blood. Electrophoresis. 2005; 26: 2749-58.10.1002/elps.200410406]Open DOISearch in Google Scholar
[2. Chen TL, Shen WJ, Kraemer FB. Human BMP-7/OP-1 induces the growth and differentiation of adipocytes and osteoblasts in bone marrow stromal cell cultures. J Cell Biochem. 2001; 2:187-99.10.1002/jcb.1145]Search in Google Scholar
[3. Allan EH, Ho PW, Umezawa A, Hata J, Makishima F, Gillespie MT, et al. Differentiation potential of a mouse bone marrow stromal cell line. J Cell Biochem. 2003; 1: 158-69.10.1002/jcb.10614]Open DOISearch in Google Scholar
[4. Mueller SM, Glowacki J. Age-related decline in the osteogenic potential of human bone marrow cells cultured in three-dimensional collagen sponges. J Cell Biochem. 2001; 82:583-90.10.1002/jcb.1174]Open DOISearch in Google Scholar
[5. Stenderup K, Justesen J, Clausen C, Kassem M. Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells. Bone. 2003:33:919-26.10.1016/j.bone.2003.07.005]Open DOISearch in Google Scholar
[6. Lu LL, Liu YJ, Yang SG, Zhao QJ, Wang X, Gong W, et al. Isolation and characterization of human umbilical cord mesenchymal stem cells with hematopoiesis-supportive function and other potentials. Haematologica. 2006; 91:1017-26.]Search in Google Scholar
[7. Romanov YA, Svintsitskaya VA, Smirnov VN. Searching for alternative sources of postnatal human mesenchymal stem cells: Candidate MSC-like cells from umbilical cord. Stem Cells. 2003; 21:105-10.10.1634/stemcells.21-1-105]Open DOISearch in Google Scholar
[8. Baksh D, Yao R, Tuan RS. Comparison of proliferative and multilineage differentiation potential of human mesenchymal stem cells derived from umbilical cord and bone marrow. Stem Cells. 2007; 25:1384-92.10.1634/stemcells.2006-0709]Open DOISearch in Google Scholar
[9. Wang HS, Hung SC, Peng ST, Huang CC, Wei HM, Guo YJ, et al. Mesenchymal stem cells in the Wharton’s jelly of the human umbilical cord. Stem Cells. 2004; 22: 1330-7.10.1634/stemcells.2004-0013]Open DOISearch in Google Scholar
[10. Chang YJ, Shih DT, Tseng CP, Hsieh TB, Lee DC, Hwang SM. Disparate mesenchyme-lineage tendencies in mesenchymal stem cells from human bone marrow and umbilical cord blood. Stem Cells. 2006; 24: 679-85.10.1634/stemcells.2004-0308]Open DOISearch in Google Scholar
[11. Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, et al. The novel zinc nger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell. 2002; 108: 17-29.10.1016/S0092-8674(01)00622-5]Open DOISearch in Google Scholar
[12. Omoteyama K, Takagi M. The effects of Sp7/Osterix gene silencing in the chondroprogenitor cell line, ATDC5. Biochem Biophys Res Commun. 2010; 403:242-6.10.1016/j.bbrc.2010.11.023]Search in Google Scholar
[13. Lee JS, Lee JM, Im GI. Electroporation-mediated transfer of Runx2 and Osterix genes to enhance osteogenesis of adipose stem cells. Biomaterials. 2011; 32:760-8.10.1016/j.biomaterials.2010.09.042]Open DOISearch in Google Scholar
[14. Yoshida CA, Furuichi T, Fujita T, Fukuyama R, Kanatani N, Kobayashi S, et al. Core-binding factor beta interacts with Runx2 and is required for skeletal development. Nat Genet. 2002; 32:633-8.10.1038/ng1015]Open DOISearch in Google Scholar
[15. Cao Y, Zhou Z, de Crombrugghe B, Nakashima K, Guan H, Duan X, et al. Osterix, a transcription factor for osteoblast differentiation, mediates antitumor activity in murine osteosarcoma. Cancer Res. 2005; 65: 1124-8.10.1158/0008-5472.CAN-04-2128]Open DOISearch in Google Scholar
[16. Tu Q, Valverde P, Chen J. Osterix enhances proliferation and osteogenic potential of bone marrow stromal cells. Biochem Biophys Res Commun. 2006; 341: 1257-65.10.1016/j.bbrc.2006.01.092]Search in Google Scholar
[17. Ishige I, Nagamura-Inoue T, Honda MJ, Harnprasopwat R, Kido M, Sugimoto M, et al. Comparison of mesenchymal stem cells derived from arterial, venous, and Wharton’s jelly explants of human umbilical cord. Int J Hematol. 2009; 90:261-9.10.1007/s12185-009-0377-3]Open DOISearch in Google Scholar
[18. Xu J, Liao W, Gu D, Liang L, Liu M, Du W, et al. Neural ganglioside GD2 identifies a subpopulation of mesenchymal stem cells in umbilical cord. Cell Physiol Biochem. 2009; 23:415-24.10.1159/000218188]Open DOISearch in Google Scholar
[19. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods.1983; 65: 55-63.10.1016/0022-1759(83)90303-4]Open DOISearch in Google Scholar
[20. Betz VM, Betz OB, Harris MB, Vrahas MS, Evans CH. Bone tissue engineering and repair by gene therapy. Front Biosci. 2008; 13:833-41.10.2741/272417981592]Open DOISearch in Google Scholar
[21. Gamradt SC, Lieberman JR. Genetic modification of stem cells to enhance bone repair. Ann Biomed Eng. 2004; 32:136-47.10.1023/B:ABME.0000007798.78548.b8]Open DOISearch in Google Scholar
[22. Kimelman N, Pelled G, Helm GA, Huard J, Schwarz EM, Gazit D. Review: gene- and stem cell-based therapeutics for bone regeneration and repair. Tissue Eng. 2007; 13:1135-50.10.1089/ten.2007.0096]Open DOISearch in Google Scholar
[23. Harada S, Rodan GA. Control of osteoblast function and regulation of bone mass. Nature. 2003; 423:349-55.10.1038/nature01660]Search in Google Scholar
[24. Olsen BR, Reginato AM, Wang W. Bone development. Annu Rev Cell Dev Biol. 2000; 16:191-220.10.1146/annurev.cellbio.16.1.191]Open DOISearch in Google Scholar
[25. Wu X, Wang S, Chen B, An X. Muscle-derived stem cells: isolation, characterization, differentiation, and application in cell and gene therapy. Cell Tissue Res. 2010; 340:549-67.10.1007/s00441-010-0978-4]Search in Google Scholar
[26. Huang W, Rudkin GH, Carlsen B, Ishida K, Ghasri P, Anvar B, et al. Overexpression of BMP-2 modulates morphology, growth, and gene expression in osteoblastic cells. Exp Cell Res. 2000; 2274:226-34.]Search in Google Scholar
[27. Cho HH, Park HT, Kim YJ, Bae YC, Suh KT, Jung JS. Induction of osteogenic differentiation of human mesenchymal stem cells by histone deacetylase inhibitors. J Cell Biochem. 2005; 96:533-42.10.1002/jcb.20544]Open DOISearch in Google Scholar
[28. Igarashi M, Kamiya N, Hasegawa M, Kasuya T, Takahashi T, Takagi M. Inductive effects of dexamethasone on the gene expression of Cbfa1, Osterix and bone matrix proteins during differentiation of cultured primary rat osteoblasts. J Mol Histol. 2004; 35:3-10.10.1023/B:HIJO.0000020883.33256.fe]Search in Google Scholar
[29. Aubin JE. Advances in the osteoblast lineage. Biochem Cell Biol. 1998; 76:899-910.10.1139/o99-005]Open DOISearch in Google Scholar
[30. Beck GR Jr, Sullivan EC, Moran E, Zerler B. Relationship between alkaline phosphatase levels, osteopontin expression, and mineralization in differentiating MC3T3-E1 osteoblasts. J Cell Biochem. 1998; 68:269-80.10.1002/(SICI)1097-4644(19980201)68:2<269::AID-JCB13>3.0.CO;2-A]Open DOISearch in Google Scholar
[31. Sun S, Wang Z, Hao Y. Osterix overexpression enhances osteoblast differentiation of muscle satellite cells in vitro.Int J Oral Maxillofac Surg. 2008; 37:350-6.10.1016/j.ijom.2007.11.024]Open DOISearch in Google Scholar
[32. Kim YJ, Kim HN, Park EK, Lee BH, Ryoo HM, Kim SY, et al. The bone-related Zn nger transcription factor Osterix promotes proliferation of mesenchymal cells. Gene. 2006; 366:145-51.10.1016/j.gene.2005.08.021]Search in Google Scholar
[33. Huang S, Wang Z. Influence of platelet-rich plasma on proliferation and osteogenic differentiation of skeletal muscle satellite cells: an in vitro study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010; 110:453-62.10.1016/j.tripleo.2010.02.00920452253]Open DOISearch in Google Scholar
[34. Standal T, Borset M, Sundan A. Role of osteopontin in adhesion, migration, cell survival and bone remodeling. Exp Oncol. 2004; 26:179-84.]Search in Google Scholar
[35. Gericke A, Qin C, Spevak L, Fujimoto Y, Butler WT, Sorensen ES, et al. Importance of phosphorylation for osteopontin regulation of biomineralization. Calcif Tissue Int. 2005; 77:45-54.10.1007/s00223-004-1288-1145141416007483]Open DOISearch in Google Scholar
[36. Golub EE. Role of Matrix Vesicles in Biomineralization. Biochim Biophys Acta. 2009; 1790: 1592-8.10.1016/j.bbagen.2009.09.006278368919786074]Search in Google Scholar
[37. Allori AC, Sailon AM, Warren SM. Biological basis of bone formation, remodeling, and repair-part II: extracellular matrix. Tissue Eng Part B Rev. 2008; 14: 275-83.10.1089/ten.teb.2008.008319183102]Open DOISearch in Google Scholar
[38. Gersbach CA, Byers BA, Pavlath GK, Garcia AJ. Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype. Exp Cell Res. 2004; 300:406-17.10.1016/j.yexcr.2004.07.03115475005]Search in Google Scholar
[39. Yang S, Wei D, Wang D, Phimphilai M, Krebsbach PH, Franceschi RT. In vitro and in vivo synergistic interactions between the Runx2/Cbfa1 transcription factor and bone morphogenetic protein-2 in stimulating osteoblast differentiation. J Bone Miner Res. 2003; 18: 705-15.10.1359/jbmr.2003.18.4.705356515912674331]Open DOISearch in Google Scholar
[40. Byers BA, Pavlath GK, Murphy TJ, Karsenty G, Garcia AJ. Cell-type-dependent up-regulation of in vitro mineralization after overexpression of the osteoblast-specific transcription factor Runx2/Cbfal. J Bone Miner Res. 2002; 17:1931-44.10.1359/jbmr.2002.17.11.193112412799]Open DOISearch in Google Scholar