<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Staphylococci are among the most frequent human microbiota components associated with the high level of bloodstream infection (BSI) episodes. In predisposed patients, there is a high risk of transformation of BSI episodes to sepsis. Both bacterial and host factors are crucial for the outcomes of BSI and sepsis. The highest rates of BSI episodes were reported in Africa, where these infections were up to twice as high as the European rates. However, there remains a great need to analyze African data for comprehensive quantification of staphylococcal BSI prevalence. The lowest rates of BSI exist in Australia. Asian, European, and North American data showed similar frequency values. Worldwide analysis indicated that both <italic>Staphylococcus aureus</italic> and coagulase-negative staphylococci (CoNS) are the most frequent BSI agents. In the second group, the most prevalent species was <italic>Staphylococcus epidermidis</italic>, although CoNS were not identified at the species level in many studies. The lack of a significant worldwide decrease in BSI episodes indicates a great need to implement standardized diagnostic methods and research etiological factors using advanced genetic methods.</p></abstract>

Staphylococci are among the most frequent human microbiota components associated with the high level of bloodstream infection (BSI) episodes. In predisposed patients, there is a high risk of transformation of BSI episodes to sepsis. Both bacterial and host factors are crucial for the outcomes of BSI and sepsis. The highest rates of BSI episodes were reported in Africa, where these infections were up to twice as high as the European rates. However, there remains a great need to analyze African data for comprehensive quantification of staphylococcal BSI prevalence. The lowest rates of BSI exist in Australia. Asian, European, and North American data showed similar frequency values. Worldwide analysis indicated that both Staphylococcus aureus and coagulase-negative staphylococci (CoNS) are the most frequent BSI agents. In the second group, the most prevalent species was Staphylococcus epidermidis, although CoNS were not identified at the species level in many studies. The lack of a significant worldwide decrease in BSI episodes indicates a great need to implement standardized diagnostic methods and research etiological factors using advanced genetic methods.

Epidemiology and Pathogenesis of <italic>Staphylococcus</italic> Bloodstream Infections in Humans: a Review

Polish Journal of Microbiology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Epidemiology and Pathogenesis of  Bloodstream Infections in Humans: a Review

Staphylococci are among the most frequent human microbiota components associated with the high level of bloodstream infection (BSI) episodes. In predisposed...

Epidemiology and Pathogenesis of Staphylococcus Bloodstream Infections in Humans: a Review

Article Category: minireview

Publié en ligne: 19 mars 2021

Pages: 13 - 23

Reçu: 22 oct. 2020

Accepté: 12 janv. 2021

DOI: https://doi.org/10.33073/pjm-2021-005

Mots clés
bacteremia, carriage, infection, sepsis,

© 2021 Klaudia Lisowska-Łysiak et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Epidemiology and Pathogenesis of Staphylococcus Bloodstream Infections in Humans: a Review

Article Category: minireview

Publié en ligne: 19 mars 2021

Pages: 13 - 23

Reçu: 22 oct. 2020

Accepté: 12 janv. 2021

DOI: https://doi.org/10.33073/pjm-2021-005

Mots clésbacteremia, carriage, infection, sepsis,

© 2021 Klaudia Lisowska-Łysiak et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Mots clés
bacteremia, carriage, infection, sepsis,