Analysis Of Family Cases With Type I Diabetes Mellitus In A Group Of Pediatric Patients From Constanţa County
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16 févr. 2013
À propos de cet article
Publié en ligne: 16 févr. 2013
Pages: 13 - 18
DOI: https://doi.org/10.2478/v10307-012-0002-1
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© 2013
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
The aim of this study was to present the cases with family history of type 1 diabetes in a group of pediatric patients from the Clinic of Pediatrics, Constanta County Hospital, and to analyze the risk for relatives conferred by presence of particular DR genotypes. 8 out of 60 index cases had relatives affected with type 1 diabetes (13.33%). Of these, four had firstdegree relatives affected (6.67%) and were presented here. Although high-risk genotypes were more frequent in the group of familial cases, no association was found between DR genotype and family history of type 1 diabetes when statistical significance was tested (p value 0.119).