<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><p>Introduction. In occlusive diseases of carotid arteries may be involved salivary glands which play important role in oral and general homeostasis. Aim of the study. The purpose of this study was histomorphological evaluation of rabbit's salivary glands after regional reduction af arterial circulation and reconstruction of ligated common carotid arteries comparing with normal histological sight. Materials and methods. The experiments were authorized by the Animal Ethics Committee of the Latvian Food and Veterinary Service. 20 male Californian rabbits weighing approximately 3 kg were used. Under intravenous general anesthesia and local anesthesia the ligature of a. carotis communis dextra was done. After 28 days 10 rabbits were sacrificed and samples were taken from all major salivary glands and histological measured acinar dimensions and acinar epithelial cell. For rest 10 rabbits under the general anesthesia were performed revascularization of a. carotis communis dextra. After 28 days the rabbits were sacrificed with intrapulmonal injection of T61. The acini dimensions and acinar epithelial cell diameter in microns in all glands were measured except buccal glands were measured. Results. In ischemic conditions all glands react with decrease of acinar epithelial cell diameter and also diametr of functional unit of salivary gland. After revascularisation reestablishment of acini and secretory epithelial cells was observed. Conclusions. Rabbit's salivary glands have potential to recovery in diminished after ligation of ipsilateral common carotid artery size of acini and secretory epithelium after 4 week ischemia if the blood supply is reestabilished.</p></abstract>

Introduction. In occlusive diseases of carotid arteries may be involved salivary glands which play important role in oral and general homeostasis. Aim of the study. The purpose of this study was histomorphological evaluation of rabbit's salivary glands after regional reduction af arterial circulation and reconstruction of ligated common carotid arteries comparing with normal histological sight. Materials and methods. The experiments were authorized by the Animal Ethics Committee of the Latvian Food and Veterinary Service. 20 male Californian rabbits weighing approximately 3 kg were used. Under intravenous general anesthesia and local anesthesia the ligature of a. carotis communis dextra was done. After 28 days 10 rabbits were sacrificed and samples were taken from all major salivary glands and histological measured acinar dimensions and acinar epithelial cell. For rest 10 rabbits under the general anesthesia were performed revascularization of a. carotis communis dextra. After 28 days the rabbits were sacrificed with intrapulmonal injection of T61. The acini dimensions and acinar epithelial cell diameter in microns in all glands were measured except buccal glands were measured. Results. In ischemic conditions all glands react with decrease of acinar epithelial cell diameter and also diametr of functional unit of salivary gland. After revascularisation reestablishment of acini and secretory epithelial cells was observed. Conclusions. Rabbit's salivary glands have potential to recovery in diminished after ligation of ipsilateral common carotid artery size of acini and secretory epithelium after 4 week ischemia if the blood supply is reestabilished.

Histomorphology of Salivary Glands after Ligature and Reconstruction of Common Carotid Artery in Rabbits

Department of Oral and Maxillofacial Surgery, Riga Stradins University, Latvia

Institute of Anatomy and Anthropology, Riga Stradins University, Latvia

Department of Pathology, Riga Stradins University, Latvia

Department of Reconstructive and Plastic Surgery, Austrumu Clinical University Hospital, Riga, Latvia

Acta Chirurgica Latviensis

Introduction. In occlusive diseases of carotid arteries may be involved salivary glands which play important role in oral and general homeostasis. Aim of the...

Histomorphology of Salivary Glands after Ligature and Reconstruction of Common Carotid Artery in Rabbits

Publié en ligne: 18 août 2010

Pages: 45 - 49

DOI: https://doi.org/10.2478/v10163-010-0009-2

Mots clés
salivary glands, histology, carotid artery ligature, reconstruction

This content is open access.

Histomorphology of Salivary Glands after Ligature and Reconstruction of Common Carotid Artery in Rabbits

Publié en ligne: 18 août 2010

Pages: 45 - 49

DOI: https://doi.org/10.2478/v10163-010-0009-2

Mots cléssalivary glands, histology, carotid artery ligature, reconstruction

This content is open access.

Mots clés
salivary glands, histology, carotid artery ligature, reconstruction