<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><p>Surface electrogastrography (EGG) is a non-invasive means of recording gastric myoelectric activity or slow waves from cutaneous leads placed over the stomach. This paper provides a comprehensive review of preclinical EGG. Our group recently set up and worked out the methods for EGG in experimental pigs. We gained our initial experience in the use of EGG in assessment of porcine gastric myoelectric activity after volume challenge and after intragastric administration of itopride and erythromycin. The mean dominant frequency in pigs is comparable with that found in humans. EGG in experimental pigs is feasible. Experimental EGG is an important basis for further preclinical projects in pharmacology and toxicology.</p></abstract>

Surface electrogastrography (EGG) is a non-invasive means of recording gastric myoelectric activity or slow waves from cutaneous leads placed over the stomach. This paper provides a comprehensive review of preclinical EGG. Our group recently set up and worked out the methods for EGG in experimental pigs. We gained our initial experience in the use of EGG in assessment of porcine gastric myoelectric activity after volume challenge and after intragastric administration of itopride and erythromycin. The mean dominant frequency in pigs is comparable with that found in humans. EGG in experimental pigs is feasible. Experimental EGG is an important basis for further preclinical projects in pharmacology and toxicology.

Preclinical electrogastrography in experimental pigs

Institute of Experimental Biopharmaceutics, Joint Research Centre of Czech Academy of Sciences and PRO.MED.CS Praha as, Hradec Králové, Czech Republic

University Department of Gastroenterology, Faculty of Medicine at Hradec Králové, Charles University in Praha, Hradec Králové, Czech Republic

Department of Internal Medicine, Faculty of Medicine, Charles University in Praha, University Teaching Hospital, Hradec Králové, Czech Republic

Interdisciplinary Toxicology

{"article-title":"Preclinical electrogastrography in experimental pigs"}

Surface electrogastrography (EGG) is a non-invasive means of recording gastric myoelectric activity or slow waves from cutaneous leads placed over the stomach....

Preclinical electrogastrography in experimental pigs

Publié en ligne: 30 juil. 2010

Pages: 53 - 58

DOI: https://doi.org/10.2478/v10102-010-0011-5

Mots clés
electrogastrography, preclinical studies, experimental pig

This content is open access.

Preclinical electrogastrography in experimental pigs

Publié en ligne: 30 juil. 2010

Pages: 53 - 58

DOI: https://doi.org/10.2478/v10102-010-0011-5

Mots cléselectrogastrography, preclinical studies, experimental pig

This content is open access.

Mots clés
electrogastrography, preclinical studies, experimental pig