<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><p>Biosensors are analytical devices being approachable for multiple analytes assay. Here, biosensors with intercepted acetylcholinesterase (AChE) or butyrylcholinesterase (BChE) are presented as tool for assay of anticholinergic compounds such as pesticides, nerve agents and some natural toxins. Principle of assay is based on evaluation of cholinesterase activity and its pertinent decrease in presence of analyte. Nerve agents, pesticides, anticholinergic drugs useable for treatment of Alzheimer's disease as well as myasthenia gravis and aflatoxins are enlisted as compounds simply analyzable by cholinesterase biosensors.</p></abstract>

Biosensors are analytical devices being approachable for multiple analytes assay. Here, biosensors with intercepted acetylcholinesterase (AChE) or butyrylcholinesterase (BChE) are presented as tool for assay of anticholinergic compounds such as pesticides, nerve agents and some natural toxins. Principle of assay is based on evaluation of cholinesterase activity and its pertinent decrease in presence of analyte. Nerve agents, pesticides, anticholinergic drugs useable for treatment of Alzheimer's disease as well as myasthenia gravis and aflatoxins are enlisted as compounds simply analyzable by cholinesterase biosensors.

Cholinesterase based amperometric biosensors for assay of anticholinergic compounds

Center of Advanced Studies, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic

Interdisciplinary Toxicology

Biosensors are analytical devices being approachable for multiple analytes assay. Here, biosensors with intercepted acetylcholinesterase (AChE) or...

Cholinesterase based amperometric biosensors for assay of anticholinergic compounds

Publié en ligne: 19 juin 2009

Pages: 52 - 54

DOI: https://doi.org/10.2478/v10102-009-0011-5

Mots clés
biosensor, acetylcholinesterase, butyrylcholinesterase, amperometry, organophophates, organophosphonates, carbamates

This content is open access.

Cholinesterase based amperometric biosensors for assay of anticholinergic compounds

Publié en ligne: 19 juin 2009

Pages: 52 - 54

DOI: https://doi.org/10.2478/v10102-009-0011-5

Mots clésbiosensor, acetylcholinesterase, butyrylcholinesterase, amperometry, organophophates, organophosphonates, carbamates

This content is open access.

Mots clés
biosensor, acetylcholinesterase, butyrylcholinesterase, amperometry, organophophates, organophosphonates, carbamates