Possibilities of alternative generation II biotests at Artemia

The meaning of alternative biotests is described and discussed. The paper also deals with the possible application of the developmental studies of the sea Artemia franciscana nauplinus. Five-day biotests including the validation criteria are described. The possibilities of the biotests are very wide. Additionally to the standard applications in ecotoxicology, there is a possibility of modelling pharmacological experiments or monitoring the effects of ionizing radiation and the interaction with other chemicals.