Development of directly compressible metformin hydrochloride by the spray-drying technique

R. F. Shangraw, Compressed Tablets by Direct Compression, in Pharmaceutical Dosage Forms: Tablets (Eds. H. A. Leiberman, L. Lachman and J. B. Schwatz), Marcel Dekker, New York 1990, pp. 195-246.Search in Google Scholar

D. Stepensky, M. Friedman, W. Srour, I. Raz and A. Hoffman, Preclinical evaluation of pharmacokinetic-pharmacodynamic rationale for oral CR metformin formulation, J. Control. Rel. 71 (2001) 107-115; DOI: 10.1016/S0168-3659(00)00374-6.10.1016/S0168-3659(00)00374-6Search in Google Scholar

O. Defang, N. Shufang, L. Wei, G. Hong, L. Hui and P. Weisan, In-vivo and in-vitro evaluation of two extended release preparations of combination metformin and glipizide, Drug Dev. Ind. Pharm. 31 (2005) 677-685; DOI: 10.1080/03639040500216410.10.1080/03639040500216410Search in Google Scholar

J. L. Ford, H. A. Garekani, M. H. Rubinstein and A. Rajabi-Siahboomi, Highly compressible paracetamol-I: Crystallization and characterization, Int. J. Pharm. 208 (2000) 87-99; DOI: 10.1016/S0378-5173(00)00550-0.10.1016/S0378-5173(00)00550-0Search in Google Scholar

J. R. Davey, The role of additives in precipitation processes, in Industrial Crystallization (Eds. S. J. Jancic and E. J. De Jong), Elsevier, Amsterdam 1982, pp. 123-135.Search in Google Scholar

A. S. Michaels and A. R. Colville, The effect of surface active agents on crystal growth rate and crystal habit, J. Phys. Chem. 64 (1960) 13-19; DOI: 10.1021/j100830a005.10.1021/j100830a005Search in Google Scholar

J. Broadhead, S. K. Edmond Rouan and C. T. Rhodes, The spray drying of pharmaceuticals, Drug Dev. Ind. Pharm. 18 (1992) 1169-1206; DOI: 10.3109/03639049209046327.10.3109/03639049209046327Search in Google Scholar

A. Nokhodchi, N. Bolourtchian and R. Dinarvand, Crystal modification of phenytoin using different solvents and crystallization conditions, Int. J. Pharm. 250 (2003) 85-97; DOI: 10.1016/S0378-5173(02)00488-X.10.1016/S0378-5173(02)00488-XSearch in Google Scholar

P. D. Martino, M. Scoppa, E. Jorris, G. F. Palmieri, C. Andres, Y. Pourcelot and S. Martelli, The spray drying of acetazolamide as method to modify crystal properties and to improve compression behaviour, Int. J. Pharm. 213 (2001) 209-221; DOI: 10.1016/S0378-5173(00)00675-X.10.1016/S0378-5173(00)00675-XSearch in Google Scholar

R. L. Carr, Evaluating flow properties of solids, Chem. Eng. 72 (1965) 163-168.Search in Google Scholar

J. Staniforth, Powder flow, in Pharmaceutics: The Science of Dosage Form Design (Ed. M. E. Aulton), 2nd ed., Churchill Livingstone, London 2002, pp. 197-210.Search in Google Scholar

R. W. Heckel, Density-pressure relationship in powder compaction, Trans. Metal. Soc. AIME 221 (1961) 671-675.Search in Google Scholar

R. W. Heckel, An analysis of powder compaction phenomena, Trans. Metal. Soc. AIME 221 (1961) 1001-1008.Search in Google Scholar

K. Kawakita and K. H. Ludde, Some consideration of powder compression equations, Powder Tehnol. 4 (1971) 61-68; DOI: 10.1016/0032-5910(71)80001-3.10.1016/0032-5910(71)80001-3Search in Google Scholar

United States Pharmacopoeia 29, National Formulary 24, USP Convention, Rockville 2006.Search in Google Scholar