Effects of drug solubility on the release kinetics of water soluble and insoluble drugs from HPMC based matrix formulations

P. Colombo, R. Bettini, G. Massimo, P. L. Catellani, P. Santi and N. A. Peppas, Drug diffusion front movement is important in drug release control from swellable matrix tablets, J. Pharm. Sci. 84 (1995) 991-997; DOI: 10.1002/jps.2600840816.10.1002/jps.2600840816Search in Google Scholar

Controlled Release Technologies, A. F. Kydonieus (Ed.), Vol. 1, CRC Press, Boca Raton 1980.Search in Google Scholar

F. Viega, T. Salsa and E. Pina, Oral controlled release dosage forms. II. Glassy polymers in hydrophilic matrices, Drug Dev. Ind. Pharm. 24 (1998) 1-9; DOI: 10.3109/03639049809082346.10.3109/03639049809082346Search in Google Scholar

D. A. Alderman, A review of cellulose ethers in hydrophilic matrices for oral controlled-release dosage forms, Int. J. Pharm. Tech. Prod. Mfr. 5 (1984) 1-9.Search in Google Scholar

M. R. Siahi, M. B. Jalali, F. Monajjemzadeh, F. Ghaffari and S. Azarmi, Design and evaluation of 1- and 3-layer matrices of verapamil hydrochloride for sustaining its release, AAPS PharmSci-Tech 4 (2005) 626-632; DOI: 10.1208/pt060477.10.1208/pt060477Search in Google Scholar

T. Higuchi, Mechanism of sustained-action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices, J. Pharm. Sci. 52 (1963) 1145-1149; DOI: 10.1002/jps.2600521210.10.1002/jps.2600521210Search in Google Scholar

P. L. Ritger and N. A. Peppas, A simple equation for description of solute release II. Fickian and anomalous release from swellable devices, J. Control. Rel. 5 (1987) 37-42; DOI: 10.1016/0168-3659(87)90035-6.10.1016/0168-3659(87)90035-6Search in Google Scholar

R. W. Korsmeyer, R. Gurny, E. Docler, P. Buri and N. A. Peppas, Mechanism of solute release from porous hydrophilic polymers, Int. J. Pharm. 15 (1983) 25-35; DOI: 10.1016/0378-5173(83)90064-9.10.1016/0378-5173(83)90064-9Search in Google Scholar

R. Reynold, S. N. Gehree, A. S. Hussain and L. S. Shenonda, Polymer erosion and drug release characterization of hydroxypropyl methylcellulose matrices, J. Pharm. Sci. 87 (1998) 1115-1123; DOI: 10.1021/js980004q.10.1021/js980004qSearch in Google Scholar

M. Jivraj, L. G. Martini and C. M. Thomson, An overview of different excipients useful for direct compression of tablets, Pharm. Sci. Technol. Today 3 (2000) 58-63; DOI: 10.1016/S1461-5347(99)00237-0.10.1016/S1461-5347(99)00237-0Search in Google Scholar

N. K. Ebube, A. Hikal, C. M. Wyandt, D. C. Beer, L. G. Miller and A. B. Jones, Sustained release of acetaminophen from heterogeneous matrix tablets: influence of polymer ratio, polymer loading and co-active on drug release, Pharm. Dev. Technol. 2 (1997) 161-170; DOI: 10.3109/10837459709022621.10.3109/10837459709022621Search in Google Scholar

P. R. Katikaneni, S. M. Upadrashia, S. H. Neau and A. K. Mitra, Ethyl cellulose matrix controlled-release tablets of a water soluble drug, Int. J. Pharm. 123 (1995) 119-125; DOI: 10.1016/0378-5173(95)00060-V.10.1016/0378-5173(95)00060-VSearch in Google Scholar

A. Avachat and V. Kotwal, Design and evaluation of matrix-based controlled release tablets of diclofenac sodium and chondroitin sulphate, AAPS PharmSciTech 8 (2007) 51-56; DOI: 10.1208/pt0804088.10.1208/pt0804088275055818181548Search in Google Scholar

A. Kuksal, A. K. Tiwary, N. K. Jain and S. Jain, Formulation and in vitro, in vivo evaluation of extended-release matrix tablet of zidovudine: Influence of combination of hydrophilic and hydrophobic matrix formers, AAPS PharmSciTech 7 (2006) Article 1; DOI: 10.1208/pt070101.10.1208/pt070101275070816584139Search in Google Scholar

M. Efentakis and A. Koutlis, Release of furosemide from multiple unit and single unit preparations containing different viscosity grades of sodium alginate, Pharm. Dev. Technol. 6 (2001) 91-98; DOI: 10.1081/PDT-100000048.10.1081/PDT-10000004811247279Search in Google Scholar

J. E. Mockel and B. C. Lippold, Zero order release from hydrocolloid matrices, Pharm. Res. 10 (1993) 1066-1070; DOI: 10.1023/A:1018931210396.10.1023/A:1018931210396Search in Google Scholar