[
1. Klein EY, Van Boeckel TP, Martinez EM, Pant S, Gandra S, Levin SA, et al. Global increase and geographic convergence in antibiotic consumption between 2000 and 2015. Proc Natl Acad Sci U S A. 2018;115(15):E3463-E3470.10.1073/pnas.1717295115589944229581252
]Search in Google Scholar
[
2. McWhinney BC, Wallis SC, Hillister T, Roberts JA, Lipman J, Ungerer JP. Analysis of 12 beta-lactam antibiotics in human plasma by HPLC with ultraviolet detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2010;878(22):2039-43.10.1016/j.jchromb.2010.05.02720561826
]Search in Google Scholar
[
3. Ohmori T, Suzuki A, Niwa T, Ushikoshi H, Shirai K, Yoshida S, et al. Simultaneous determination of eight β- lactam antibiotics in human serum by liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2011;879(15-16):1038-42.10.1016/j.jchromb.2011.03.00121459052
]Search in Google Scholar
[
4. Wong G, Briscoe S, McWhinney B, Ally M, Ungerer J, Lipman J, et al. Therapeutic drug monitoring of β-lactam antibiotics in the critically ill: direct measurement of unbound drug concentrations to achieve appropriate drug exposures. J Antimicrob Chemother. 2018;73(11):3087-3094.10.1093/jac/dky31430137377
]Search in Google Scholar
[
5. Drusano GL. Antimicrobial pharmacodynamics: critical interactions of ‘bug and drug’. Nat Rev Microbiol. 2004;2(4):289-300.10.1038/nrmicro86215031728
]Search in Google Scholar
[
6. Roberts JA, Paratz JD, Lipman J. Continuous infusion of beta-lactams in the intensive care unit--best way to hit the target? Crit Care Med. 2008;36(5):1663-4.10.1097/CCM.0b013e318170462518448930
]Search in Google Scholar
[
7. Roberts JA, Lipman J. Pharmacokinetic issues for antibiotics in the critically ill patient. Crit Care Med. 2009;37(3):840-5110.1097/CCM.0b013e3181961bff19237886
]Search in Google Scholar
[
8. Wolff F, Deprez G, Seyler L, Taccone F, Hites M, Gulbis B, et al. Rapid quantification of six β-lactams to optimize dosage regimens in severely septic patients. Talanta. 2013;103:153-60.10.1016/j.talanta.2012.10.02423200371
]Search in Google Scholar
[
9. McKinnon PS, Paladino JA, Schentag JJ. Evaluation of area under the inhibitory curve (AUIC) and time above the minimum inhibitory concentration (T>MIC) as predictors of outcome for cefepime and ceftazidime in serious bacterial infections. Int J Antimicrob Agents. 2008;31(4):345-51.10.1016/j.ijantimicag.2007.12.00918313273
]Search in Google Scholar
[
10. Craig W. Pharmacodynamics of antimicrobial agents as a basis for determining dosage regimens. Eur J Clin Microbiol Infect Dis. 1993;12 Suppl 1:S6-8.10.1007/BF023898708477766
]Search in Google Scholar
[
11. Jacobs MR. Optimisation of antimicrobial therapy using pharmacokinetic and pharmacodynamic parameters. Clin Microbiol Infect. 2001;7(11):589-96.10.1046/j.1198-743x.2001.00295.x11737083
]Search in Google Scholar
[
12. Roth T, Fiedler S, Mihai S, Parsch H. Determination of meropenem levels in human serum by high-performance liquid chromatography with ultraviolet detection. Biomed Chromatogr. 2017;31(5).10.1002/bmc.388027797104
]Search in Google Scholar
[
13. Zhao HY, Gu J, Lyu J, Liu D, Wang YT, Liu F, et al. Pharmacokinetic and Pharmacodynamic Efficacies of Continuous versus Intermittent Administration of Meropenem in Patients with Severe Sepsis and Septic Shock: A Prospective Randomized Pilot Study. Chin Med J (Engl). 2017;130(10):1139-1145.10.4103/0366-6999.205859544301828485312
]Search in Google Scholar
[
14. Nicolau DP. Pharmacokinetic and pharmacodynamic properties of meropenem. Clin Infect Dis. 2008; 47(Suppl 1):S32–S40.10.1086/59006418713048
]Search in Google Scholar
[
15. Kong L, Tang Y, Zhang X, Lu G, Yu M, Shi Q, et al. Pharmacokinetic/pharmacodynamic analysis of meropenem for the treatment of nosocomial pneumonia in intracerebral hemorrhage patients by Monte Carlo simulation. Ann Pharmacother. 2017;51(11):970–975.10.1177/106002801771971528677407
]Search in Google Scholar
[
16. Roberts JA, Ulldemolins M, Roberts MS, McWhinney B, Ungerer J, Paterson DL, et al. Therapeutic drug monitoring of beta-lactams in critically ill patients: proof of concept. Int J Antimicrob Agents. 2010;36(4):332-9.10.1016/j.ijantimicag.2010.06.00820685085
]Search in Google Scholar
[
17. Carlier M, Stove V, De Waele JJ, Verstraete AG. Ultrafast quantification of β-lactam antibiotics in human plasma using UPLC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2015;978-979:89-94.10.1016/j.jchromb.2014.11.03425531875
]Search in Google Scholar
[
18. Kropp, H., et al. 1976. Abstr. 16th Intersci. Conf. Antimicrob. Agents Chemother., abstr. 228. American Society for Microbiology, Washington, DC.
]Search in Google Scholar
[
19. Albers-Schonberg G, Arison BH, Hensens OD, Hirshfield J, Hoogsteen K, Kaczka EA, et al. Structure and absolute configuration of thienamycin. Journal of the American Chemical Society. 1978;100 (20):6491-6499.10.1021/ja00488a038
]Search in Google Scholar
[
20. Kahan JS, Kahan FM, Goegelman R, Currie SA, Jackson M, Stapley EO, et al. Thienamycin, a new beta-lactam antibiotic. I. Discovery, taxonomy, isolation and physical properties. J Antibiot (Tokyo). 1979;32(1):1-12.10.7164/antibiotics.32.1761989
]Search in Google Scholar
[
21. Moellering RC Jr, Eliopoulos GM, Sentochnik DE. The carbapenems: new broad spectrum beta-lactam antibiotics. J Antimicrob Chemother. 1989;24 Suppl A:1-7.10.1093/jac/24.suppl_A.12681123
]Search in Google Scholar
[
22. Basker MJ, Boon RJ, Hunter PA. Comparative antibacterial properties in vitro of seven olivanic acid derivatives: MM 4550, MM 13902, MM 17880, MM 22380, MM 22381, MM 22382 and MM 22383. J Antibiot (Tokyo). 1980;33(8):878-84.10.7164/antibiotics.33.878
]Search in Google Scholar
[
23. Fukasawa M, Sumita Y, Harabe ET, Tanio T, Nouda H, Kohzuki T, et al. Stability of meropenem and effect of 1 beta-methyl substitution on its stability in the presence of renal dehydropeptidase I. Antimicrob Agents Chemother. 1992;36(7):1577-9.10.1128/AAC.36.7.1577
]Search in Google Scholar
[
24. Kropp H, Sundelof JG, Hajdu R, Kahan FM. Metabolism of thienamycin and related carbapenem antibiotics by the renal dipeptidase, dehydropeptidase. Antimicrob Agents Chemother. 1982;22(1):62-70.10.1128/AAC.22.1.62
]Search in Google Scholar
[
25. Christensen, B. G. (1981). Structure activity relationships in beta-lactam antibiotics. In BetaLactam Antibiotics. Mode of Action, New Developments, and Future Prospects (Salton, M. E. J. & Schockman, G. D., Eds), pp.101-25. Academic Press, London.
]Search in Google Scholar
[
26. Sunagawa, M., Matsumura, H., Inoue, T., Fukasawa, N. & Kato, M. (1987). SM-7338 a new carbapenem antibiotic: structure-activity relations and physiochemical properties. In Proceedings and Abstracts of the Twenty- Seventh Interscience Conference on Antimicrobial Agents and Chemotherapy, New York, 1987. Abstract 752, p. 228. American Society for Microbiology, Washington, DC.
]Search in Google Scholar
[
27. Drusano G. Meropenem: laboratory and clinical data. Clin Microbiol Infect. 1997;3 Suppl 4:S51-S59.10.1016/S1198-743X(14)65034-5
]Search in Google Scholar
[
28. Paczkowska M, Garbacki P, Zalewski P, Talaczyńska A, Cielecka-Piontek J. [Meropenem--therapeutic recommendation after twenty years of presence on pharmaceutical market]. Postepy Higieny i Medycyny Doswiadczalnej (Online). 2014;68:441-445.10.5604/17322693.110154124864096
]Search in Google Scholar
[
29. Kipper K, Anier K, Leito I, Karjagin J, Oselin K, Herodes K. Rapid Determination of Meropenem in Biological Fluids by LC: Comparison of Various Methods for Sample Preparation and Investigation of Meropenem Stability. Chromatographia. 2009; 70(9-10): 1423–1427.10.1365/s10337-009-1304-8
]Search in Google Scholar
[
30. Dincel D, Sagirli O, Topcu G. A High-Performance Liquid Chromatographic Method for the Determination of Meropenem in Serum. J Chromatogr Sci. 2020;58(2):144-150.10.1093/chromsci/bmz08731738410
]Search in Google Scholar
[
31. Craig WA. The pharmacology of meropenem, a new carbapenem antibiotic. Clin Infect Dis. 1997;24(Suppl 2):S266–75.10.1093/clinids/24.Supplement_2.S266
]Search in Google Scholar
[
32. MacGowan AP, Wise R. Establishing MIC breakpoints and the interpretation of in vitro susceptibility tests. J Antimicrob Chemother. 2001;48 Suppl 1:17-28.10.1093/jac/48.suppl_1.1711420334
]Search in Google Scholar
[
33. Mouton JW, Touzw DJ, Horrevorts AM, Vinks AA. Comparative pharmacokinetics of the carbapenems: clinical implications. Clin Pharmacokinet. 2000;39(3):185-201.10.2165/00003088-200039030-0000211020134
]Search in Google Scholar
[
34. Mouton JW, van den Anker JN. Meropenem Clinical Pharmacokinetics. Clin. Pharmacokinet. 1995;28(4):275-286.
]Search in Google Scholar
[
35. de Louvois J. Factors influencing the assay of antimicrobial drugs in clinical samples by the agar plate diffusion method. J Antimicrob Chemother. 1982;9(4):253-65.10.1093/jac/9.4.253
]Search in Google Scholar
[
36. Fleming, A. Streptococcal meningitis treated with penicillin. Measurement of bacteriostatic power of blood and cerebrospinal fluid. Lancet. 1943;2:434-438.10.1016/S0140-6736(00)87452-8
]Search in Google Scholar
[
37. Fleming, A. (1946). Bacteriological control of penicillin therapy. In Penicillin: Its Practical Application, 1st edn (Fleming, A., Ed.), pp. 76-92. Butterworth, London.
]Search in Google Scholar
[
38. Heatley NG. A method for the assay of penicillin. Biochem J. 1944;38(1):61-65.10.1042/bj0380061125802416747749
]Search in Google Scholar
[
39. Vakulenko NA. [Determination of erythromycin in serum and urine by the agar diffusion method]. Antibiotiki. 1961;6:315-8.
]Search in Google Scholar
[
40. Bennett JV, Brodie JL, Benner EJ, Kirby WM. Simplified, accurate method for antibiotic assay of clinical specimens. Appl Microbiol. 1966;14(2):170-7.10.1128/am.14.2.170-177.19665466454959982
]Search in Google Scholar
[
41. Simon HJ, Yin EJ. Microbioassay of antimicrobial agents. Appl Microbiol. 1970;19(4):573-9.10.1128/am.19.4.573-579.19703767404986725
]Search in Google Scholar
[
42. Kabay A. Rapid quantitative microbiological assay of antibiotics and chemical preservatives of a nonantibiotic nature. Appl Microbiol. 1971;22(5):752-5.10.1128/am.22.5.752-755.19713764115132091
]Search in Google Scholar
[
43. Levison ME. Microbiological agar diffusion assay for metronidazole concentrations in serum. Antimicrob Agents Chemother. 1974;5(5):466-8.10.1128/AAC.5.5.4664289964462462
]Search in Google Scholar
[
44. Wahlig H. Eine mikrobiologische Schnellmethode zur Bestimmung von Antibiotikakonzentrationen während der Therapie [A microbiological method for the rapid determination of antibiotic concentrations during therapy (author’s transl)]. Infection. 1977;5(2):117-8.10.1007/BF0164209327723000
]Search in Google Scholar
[
45. Uihlein M, Klesel N, Seeger K. Determination of cefpirome (HR 810) in serum and urine. Infection. 1988;16(2):135-40.10.1007/BF016443233372025
]Search in Google Scholar
[
46. Janković SM, Ninković V. Monitoring of serum concentrations of antibiotics by microbiological method: a oneyear experience. Med Pregl. 1998;51(7–8):333–42.
]Search in Google Scholar
[
47. Cauwelier B, Gordts B, Descheemaecker P, Van Landuyt H. Evaluation of a disk diffusion method with cefoxitin (30 microg) for detection of methicillin-resistant Staphylococcus aureus. Eur J Clin Microbiol Infect Dis. 2004;23(5):389-92.10.1007/s10096-004-1130-815112072
]Search in Google Scholar
[
48. Bonev B, Hooper J, Parisot J. Principles of assessing bacterial susceptibility to antibiotics using the agar diffusion method. J Antimicrob Chemother. 2008;61(6):1295-301.10.1093/jac/dkn090
]Search in Google Scholar
[
49. Galani I, Kontopidou F, Souli M, Rekatsina PD, Koratzanis E, Deliolanis J, et al. Colistin susceptibility testing by Etest and disk diffusion methods. Int J Antimicrob Agents. 2008;31(5):434-9.10.1016/j.ijantimicag.2008.01.011
]Search in Google Scholar
[
50. Benedict RG, Stodola FH. Modification of an Agar Diffusion Method of Assay for Polymyxin. J Bacteriol. 1948;55(2):286.10.1128/jb.55.2.286-286.1948
]Search in Google Scholar
[
51. Kureishi A, Jewesson PJ, Bartlett KH, Cole CD, Chow AW. Application of a modified bioassay for monitoring serum teicoplanin and vancomycin in febrile neutropenic patients. Antimicrob Agents Chemother. 1990;34(9):1642-7.10.1128/AAC.34.9.1642
]Search in Google Scholar
[
52. Yamamoto CH, Pinto TJ. Rapid determination of neomycin by a microbiological agar diffusion assay using triphenyltetrazolium chloride. J AOAC Int. 1996;79(2):434-440.10.1093/jaoac/79.2.434
]Search in Google Scholar
[
53. Luis Esaú LJ, Christian Rodolfo RG, Melissa HD, Claudia Adriana CC, Rodolfo GC, Rafael FC. An alternative disk diffusion test in broth and macrodilution method for colistin susceptibility in Enterobacteriales. J Microbiol Methods. 2019;167:105765.10.1016/j.mimet.2019.105765
]Search in Google Scholar
[
54. White LO. HPLC in clinical microbiology laboratories. J Antimicrob Chemother. 1981;8(1):1-3.10.1093/jac/8.1.1
]Search in Google Scholar
[
55. Guitton J, Laffont A, Bruzeau J, Rochet-Mingret L, Bonnefoy M, Bureau J. Determination of ceftazidime in plasma using high-performance liquid chromatography and electrochemical detection. Application for individualizing dosage regimens in elderly patients. J Chromatogr B Biomed Sci Appl. 1998;719(1-2):151-7.10.1016/S0378-4347(98)00333-8
]Search in Google Scholar
[
56. Demetriades JL, Souder PR, Entwistle LA, Vincek WC, Musson DG, Bayne WF. High-performance liquid chromatographic determination of cilastatin in biological fluids. J Chromatogr. 1986;382:225-31.10.1016/S0378-4347(00)83520-3
]Search in Google Scholar
[
57. Iwaki K, Okumura N, Yamazaki M, Nimura N, Kinoshita T. Precolumn derivatization technique for highperformance liquid chromatographic determination of penicillins with fluorescence detection. J Chromatogr. 1990;504(2):359–367.10.1016/S0021-9673(01)89539-X
]Search in Google Scholar
[
58. Li J, Milne RW, Nation RL, Turnidge JD, Coulthard K, Johnson DW. A simple method for the assay of colistin in human plasma, using pre-column derivatization with 9-fluorenylmethyl chloroformate in solid-phase extraction cartridges and reversed-phase high-performance liquid chromatography. J Chromatogr B Biomed Sci Appl. 2001;761(2):167-75.10.1016/S0378-4347(01)00326-7
]Search in Google Scholar
[
59. Schulte S, Ackermann T, Bertram N, Sauerbruch T, Paar WD. Determination of the newer quinolones levofloxacin and moxifloxacin in plasma by high-performance liquid chromatography with fluorescence detection. J Chromatogr Sci. 2006;44(4):205–208.10.1093/chromsci/44.4.205
]Search in Google Scholar
[
60. De Smet J, Boussery K, Colpaert K, De Sutter P, De Paepe P, Decruyenaere J, et al. Pharmacokinetics of fluoroquinolones in critical care patients: a bio-analytical HPLC method for the simultaneous quantification of ofloxacin, ciprofloxacin and moxifloxacin in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2009;877(10):961-7.10.1016/j.jchromb.2009.02.039
]Search in Google Scholar
[
61. Greene SV, Abdalla T, Morgan SL, Bryan CS. High-performance liquid chromatographic analysis of vancomycin in plasma, bone, atrial appendage tissue and pericardial fluid. J Chromatogr. 1987;417(1):121-8.10.1016/0378-4347(87)80097-X
]Search in Google Scholar
[
62. Soto-Otero R, Mendez-Alvarez E, Sierra-Paredes G, Galan- Valiente J, Aguilar-Veiga E, Sierra-Marcuño G. A rapid method for the determination of benzylpenicillin in serum by reversed-phase HPLC. Biomed Chromatogr. 1987;2(4):177-9.10.1002/bmc.1130020411
]Search in Google Scholar
[
63. Marunaka T, Matsushima E, Maniwa M. Determination of cefodizime in biological materials by high-performance liquid chromatography. J Chromatogr. 1987;420(2):329-39.10.1016/0378-4347(87)80188-3
]Search in Google Scholar
[
64. Carlhant D, Le Bot MA, Guedes Y, Riche C, Mimouri F, Colin J, et al. Solid phase extraction and HPLC determination of spiramycin in plasma and vitreous concentrations. Biomed Chromatogr. 1989;3(1):1-4.10.1002/bmc.11300301022706358
]Search in Google Scholar
[
65. Holt DE, de Louvois J, Hurley R, Harvey D. A high performance liquid chromatography system for the simultaneous assay of some antibiotics commonly found in combination in clinical samples. J Antimicrob Chemother. 1990;26(1):107-15.10.1093/jac/26.1.1072211431
]Search in Google Scholar
[
66. Mendez-Alvarez E, Soto-Otero R, Sierra-Paredes G, Aguilar-Veiga E, Galan-Valiente J, Sierra-Marcuño G. A reversed phase liquid chromatographic method for the simultaneous determination of several common penicillins in human serum. Biomed Chromatogr. 1991;5(2):78-82.10.1002/bmc.11300502071868262
]Search in Google Scholar
[
67. Ocaña González J, Callejón Mochón M. Barragán de la Rosa F. Simultaneous Determination of Cefepime and the Quinolones Garenoxacin, Moxifloxacin and Levofloxacin in Human Urine by HPLC-UV. Microchim Acta 2005;151:39-45.10.1007/s00604-005-0391-y
]Search in Google Scholar
[
68. Xu YH, Li D, Liu XY, Li YZ, Lu J. High performance liquid chromatography assay with ultraviolet detection for moxifloxacin: validation and application to a pharmacokinetic study in Chinese volunteers. J Chromatogr B Analyt Technol Biomed Life Sci. 2010;878(32):3437-41.10.1016/j.jchromb.2010.10.02421093388
]Search in Google Scholar
[
69. Fortuna S, De Pascale G, Ragazzoni E, Antonelli M, Navarra P. Validation of a new HPLC-UV method for determination of the antibiotic linezolid in human plasma and in bronchoalveolar lavage. Biomed Chromatogr. 2013;27(11):1489-96.10.1002/bmc.294723813438
]Search in Google Scholar
[
70. Vella J, Busuttil F, Bartolo NS, Sammut C, Ferrito V, Serracino-Inglott A, et al. A simple HPLC-UV method for the determination of ciprofloxacin in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2015;989:80-5.10.1016/j.jchromb.2015.01.00625813900
]Search in Google Scholar
[
71. Palma EC, Laureano JV, de Araújo BV, Meinhardt NG, Stein AT, Dalla Costa T. Fast and sensitive HPLC/UV method for cefazolin quantification in plasma and subcutaneous tissue microdialysate of humans and rodents applied to pharmacokinetic studies in obese individuals. Biomed Chromatogr. 2018;32(8):e4254.10.1002/bmc.425429656496
]Search in Google Scholar
[
72. Ezquer-Garin C, Ferriols-Lisart R, Alós-Almiñana M, Aguilar-Aguilar G, Belda-Nacher JF, et al. Validated HPLC-UV detection method for the simultaneous determination of ceftolozane and tazobactam in human plasma. Bioanalysis. 2018;10(7):461-473.10.4155/bio-2017-025729633862
]Search in Google Scholar
[
73. Zheng Y, Wang Z, Lui G, Hirt D, Treluyer JM, Benaboud S, et al. Simultaneous quantification of levofloxacin, pefloxacin, ciprofloxacin and moxifloxacin in microvolumes of human plasma using high-performance liquid chromatography with ultraviolet detection. Biomed Chromatogr. 2019;33(5):e4506.10.1002/bmc.450630743308
]Search in Google Scholar
[
74. Kotani A, Hirai J, Hamada Y, Fujita J, Hakamata H. Determination of ceftriaxone concentration in human cerebrospinal fluid by high-performance liquid chromatography with UV detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2019;1124:161-164.10.1016/j.jchromb.2019.06.00831202181
]Search in Google Scholar
[
75. Dorn C, Schießer S, Wulkersdorfer B, Hitzenbichler F, Kees MG, Zeitlinger M. Determination of free clindamycin, flucloxacillin or tedizolid in plasma: Pay attention to physiological conditions when using ultrafiltration. Biomed Chromatogr. 2020;34(6):e4820.10.1002/bmc.482032115736
]Search in Google Scholar
[
76. Cairoli S, Simeoli R, Tarchi M, Dionisi M, Vitale A, Perioli L, et al. A new HPLC-DAD method for contemporary quantification of 10 antibiotics for therapeutic drug monitoring of critically ill pediatric patients. Biomed Chromatogr. 2020;34(10):e4880.10.1002/bmc.488032396238
]Search in Google Scholar
[
77. Roth T, Weber L, Niestroj M, Cipa F, Löscher A, Mihai S, et al. Simultaneous determination of six antibiotics in human serum by high-performance liquid chromatography with UV detection. Biomed Chromatogr. 2021;35(3):e5010.10.1002/bmc.501033119907
]Search in Google Scholar
[
78. Li YX, Neufeld K, Chastain J, Curtis A, Velagaleti P. Sensitive determination of erythromycin in human plasma by LC-MS/MS. J Pharm Biomed Anal. 1998;16(6):961-70.10.1016/S0731-7085(97)00095-2
]Search in Google Scholar
[
79. Cass RT, Villa JS, Karr DE, Schmidt DE Jr. Rapid bioanalysis of vancomycin in serum and urine by high-performance liquid chromatography tandem mass spectrometry using on-line sample extraction and parallel analytical columns. Rapid Commun Mass Spectrom. 2001;15(6):406-12.10.1002/rcm.24611291118
]Search in Google Scholar
[
80. Phillips OA, Abdel-Hamid ME, al-Hassawi NA. Determination of linezolid in human plasma by LC-MS-MS. Analyst. 2001;126(5):609-14.10.1039/b100076o11394301
]Search in Google Scholar
[
81. Jansson B, Karvanen M, Cars O, Plachouras D, Friberg LE. Quantitative analysis of colistin A and colistin B in plasma and culture medium using a simple precipitation step followed by LC/MS/MS. J Pharm Biomed Anal. 2009;49(3):760-7.10.1016/j.jpba.2008.12.01619157746
]Search in Google Scholar
[
82. Gobin P, Lemaître F, Marchand S, Couet W, Olivier JC. Assay of colistin and colistin methanesulfonate in plasma and urine by liquid chromatography-tandem mass spectrometry. Antimicrob Agents Chemother. 2010;54(5):1941-8.10.1128/AAC.01367-09286360920176909
]Search in Google Scholar
[
83. Gika HG, Michopoulos F, Divanis D, Metalidis S, Nikolaidis P, Theodoridis GA. Daptomycin determination by liquid chromatography-mass spectrometry in peritoneal fluid, blood plasma, and urine of clinical patients receiving peritoneal dialysis treatment. Anal Bioanal Chem. 2010;397(6):2191-7.10.1007/s00216-010-3639-220336449
]Search in Google Scholar
[
84. Cirić B, Jandrić D, Kilibarda V, Jović-Stosić J, Dragojević- Simić V, Vucinić S. [Simultaneous determination of amoxicillin and clavulanic acid in the human plasma by high performance liquid chromatography-mass spectrometry (UPLC/MS)]. Vojnosanit Pregl. 2010;67(11):887-92.10.2298/VSP1011887C
]Search in Google Scholar
[
85. Jin HE, Kim IB, Kim YC, Cho KH, Maeng HJ. Determination of cefadroxil in rat plasma and urine using LCMS/ MS and its application to pharmacokinetic and urinary excretion studies. J Chromatogr B Analyt Technol Biomed Life Sci. 2014;947-948:103-10.10.1016/j.jchromb.2013.12.02724412692
]Search in Google Scholar
[
86. Cazorla-Reyes R, Romero-González R, Frenich AG, Rodríguez Maresca MA, Martínez Vidal JL. Simultaneous analysis of antibiotics in biological samples by ultra high performance liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal. 2014;89:203-12.10.1016/j.jpba.2013.11.00424291112
]Search in Google Scholar
[
87. Parker SL, Lipman J, Roberts JA, Wallis SC. A simple LC-MS/MS method using HILIC chromatography for the determination of fosfomycin in plasma and urine: application to a pilot pharmacokinetic study in humans. J Pharm Biomed Anal. 2015;105:39-45.10.1016/j.jpba.2014.11.04225527980
]Search in Google Scholar
[
88. Zander J, Maier B, Suhr A, Zoller M, Frey L, Teupser D, et al. Quantification of piperacillin, tazobactam, cefepime, meropenem, ciprofloxacin and linezolid in serum using an isotope dilution UHPLC-MS/MS method with semi-automated sample preparation. Clin Chem Lab Med. 2015;53(5):781-91.10.1515/cclm-2014-074625301676
]Search in Google Scholar
[
89. Parker SL, Guerra Valero YC, Ordóñez Mejia JL, Roger C, Lipman J, Roberts JA, et al. An LC-MS/MS method to determine vancomycin in plasma (total and unbound), urine and renal replacement therapy effluent. Bioanalysis. 2017;9(12):911-924.10.4155/bio-2017-001928617036
]Search in Google Scholar
[
90. Wijma RA, Bahmany S, Wilms EB, van Gelder T, Mouton JW, Koch BCP. A fast and sensitive LC-MS/MS method for the quantification of fosfomycin in human urine and plasma using one sample preparation method and HILIC chromatography. J Chromatogr B Analyt Technol Biomed Life Sci. 2017;1061-1062:263-269.10.1016/j.jchromb.2017.07.03628759841
]Search in Google Scholar
[
91. Lefeuvre S, Bois-Maublanc J, Hocqueloux L, Bret L, Francia T, Eleout-Da Violante C, et al. A simple ultrahigh- performance liquid chromatography-high resolution mass spectrometry assay for the simultaneous quantification of 15 antibiotics in plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2017;1065-1066:50-58.10.1016/j.jchromb.2017.09.01428946125
]Search in Google Scholar
[
92. Paal M, Zoller M, Schuster C, Vogeser M, Schütze G. Simultaneous quantification of cefepime, meropenem, ciprofloxacin, moxifloxacin, linezolid and piperacillin in human serum using an isotope-dilution HPLC-MS/MS method. J Pharm Biomed Anal. 2018;152:102-110.10.1016/j.jpba.2018.01.03129414000
]Search in Google Scholar
[
93. El-Najjar N, Hösl J, Holzmann T, Jantsch J, Gessner A. UPLC-MS/MS method for therapeutic drug monitoring of 10 antibiotics used in intensive care units. Drug Test Anal. 2018;10(3):584-591.10.1002/dta.225328753737
]Search in Google Scholar
[
94. Magréault S, Leroux S, Touati J, Storme T, Jacqz- Aigrain E. UPLC/MS/MS assay for the simultaneous determination of seven antibiotics in human serum-Application to pediatric studies. J Pharm Biomed Anal. 2019;174:256-262.10.1016/j.jpba.2019.03.00431181488
]Search in Google Scholar
[
95. Decosterd LA, Mercier T, Ternon B, Cruchon S, Guignard N, Lahrichi S, et al. Validation and clinical application of a multiplex high performance liquid chromatography - tandem mass spectrometry assay for the monitoring of plasma concentrations of 12 antibiotics in patients with severe bacterial infections. J Chromatogr B Analyt Technol Biomed Life Sci. 2020;1157:122160.10.1016/j.jchromb.2020.12216032891946
]Search in Google Scholar
[
96. Pandey S, Dhanani J, Lipman J, Roberts JA, Wallis SC, Parker SL. Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: application to a pilot pharmacokinetic research study. Clin Chem Lab Med. 2020;58(2):274-284.10.1515/cclm-2019-078031714883
]Search in Google Scholar
[
97. Putnam WC, Kallem RR, Edpuganti V, Subramaniyan I, Hall RG 2nd. Development and validation of a quantitative LC-MS/MS method for the simultaneous determination of ceftolozane and tazobactam in human plasma and urine. J Chromatogr B Analyt Technol Biomed Life Sci. 2020;1159:122354.10.1016/j.jchromb.2020.12235432905989
]Search in Google Scholar
[
98. Myers CM, Blumer JL. Determination of imipenem and cilastatin in serum by high-pressure liquid chromatography. Antimicrob Agents Chemother. 1984;26(1):78-81.10.1128/AAC.26.1.78
]Search in Google Scholar
[
99. Carlucci G, Biordi L, Vicentini C, Bologna M. Determination of imipenem in human plasma, urine and tissue by high-performance liquid chromatography. J Pharm Biomed Anal. 1990;8(3):283-6.10.1016/0731-7085(90)80038-Q
]Search in Google Scholar
[
100. al-Meshal MA, Ramadan MA, Lotfi KM, Shibl AM. Determination of meropenem in plasma by high-performance liquid chromatography and a microbiological method. J Clin Pharm Ther. 1995;20(3):159-63.10.1111/j.1365-2710.1995.tb00642.x
]Search in Google Scholar
[
101. Augey V, Grosse PY, Albert G, Audran M, Bressolle F. High-performance liquid chromatographic determination of tazobactam and piperacillin in human plasma and urine. J Chromatogr B Biomed Appl. 1996;682(1):125-36.10.1016/0378-4347(96)00049-7
]Search in Google Scholar
[
102. Elkhaïli H, Niedergang S, Pompei D, Linger L, Leveque D, Jehl F. High-performance liquid chromatographic assay for meropenem in serum. J Chromatogr B Biomed Appl. 1996;686(1):19-26.10.1016/S0378-4347(96)00205-8
]Search in Google Scholar
[
103. Garcia-Capdevila L, López-Calull C, Arroyo C, Moral MA, Mangues MA, Bonal J. Determination of imipenem in plasma by high-performance liquid chromatography for pharmacokinetic studies in patients. J Chromatogr B Biomed Sci Appl. 1997;692(1):127-32.10.1016/S0378-4347(96)00498-7
]Search in Google Scholar
[
104. Bompadre S, Ferrante L, De Martinis M, Leone L. Determination of meropenem in serum by high-performance liquid chromatography with column switching. Journal of Chromatography A. 1998;812(1–2):249–253.10.1016/S0021-9673(98)00249-0
]Search in Google Scholar
[
105. Farin D, Kitzes-Cohen R, Piva G, Gozlan I. High performance liquid chromatography method for the determination of meropenem in human plasma. Chromatographia. 1999;49:253–255.10.1007/BF02467552
]Search in Google Scholar
[
106. Özkan Y, Küçükgüzel İ, Özkan SA, Aboul-Enein, HY. A rapid, sensitive high performance liquid chromatographic method for the determination of meropenem in pharmaceutical dosage form, human serum and urine. Biomedical Chromatography. 2001;15(4):263–266.10.1002/bmc.68
]Search in Google Scholar
[
107. Robatel C, Buclin T, Eckert P, Schaller MD, Biollaz J, Decosterd LA. Determination of meropenem in plasma and filtrate-dialysate form patients under continuous veno-venous haemodiafiltration by SPE-LC. J Pharmaceut Biomed. 2002;29(1-2):17–33.10.1016/S0731-7085(02)00022-5
]Search in Google Scholar
[
108. Gordien JB, Boselli E, Fleureau C, Allaouchiche B, Janvier G, Lalaude O, et al. Determination of free ertapenem in plasma and bronchoalveolar lavage by high-performance liquid chromatography with ultraviolet detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2006;830(2):218-23.10.1016/j.jchromb.2005.10.03716290251
]Search in Google Scholar
[
109. Mundkowski RG, Majcher-Peszynska J, Burkhardt O, Welte T, Drewelow B. A new simple HPLC assay for the quantification of ertapenem in human plasma, lung tissue, and broncho-alveolar lavage fluid. J Chromatogr B Analyt Technol Biomed Life Sci. 2006;832(2):231-5.10.1016/j.jchromb.2006.01.00516488198
]Search in Google Scholar
[
110. Ikeda K, Ikawa K, Morikawa N, Miki M, Nishimura S, Kobayashi M. High-performance liquid chromatography with ultraviolet detection for real-time therapeutic drug monitoring of meropenem in plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2007;856(1-2):371-5.10.1016/j.jchromb.2007.05.04317581801
]Search in Google Scholar
[
111. Sutherland C, Nicolau DP. Development of an HPLC method for the determination of doripenem in human and mouse serum. J Chromatogr B Analyt Technol Biomed Life Sci. 2007;853(1-2):123-6.10.1016/j.jchromb.2007.03.00417392039
]Search in Google Scholar
[
112. D’Avolio A, Baietto L, De Rosa FG, Garazzino S, Sciandra M, Siccardi M, et al. A simple and fast method for quantification of ertapenem using meropenem as internal standard in human plasma in a clinical setting. Ther Drug Monit. 2008;30(1):90-4.10.1097/FTD.0b013e31815f4f7e18223468
]Search in Google Scholar
[
113. Bias M, Frey OR, Köberer A. HPLC-Methode zur quantitativen Bestimmung von Meropenem im Serum. Krankenhauspharmazie. 2010;31:482-485.
]Search in Google Scholar
[
114. Pickering M, Brown S. Quantification and validation of HPLC-UV and LC-MS assays for therapeutic drug monitoring of ertapenem in human plasma. Biomed Chromatogr. 2013;27(5):568-74.10.1002/bmc.282923065850
]Search in Google Scholar
[
115. Chan CY, Chan K, French GL. Rapid high performance liquid chromatographic assay of cephalosporins in biological fluids. J Antimicrob Chemother. 1986;18(4):537-45.10.1093/jac/18.4.5373771435
]Search in Google Scholar
[
116. Isla A, Arzuaga A, Maynar J, Gascón AR, Solinís MA, Corral E, et al. Determination of ceftazidime and cefepime in plasma and dialysate-ultrafiltrate from patients undergoing continuous veno-venous hemodiafiltration by HPLC. J Pharm Biomed Anal. 2005;39(5):996-1005.10.1016/j.jpba.2005.05.02716026959
]Search in Google Scholar
[
117. Denooz R, Charlier C. Simultaneous determination of five beta-lactam antibiotics (cefepim, ceftazidim, cefuroxim, meropenem and piperacillin) in human plasma by high-performance liquid chromatography with ultraviolet detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2008;864(1-2):161-7.10.1016/j.jchromb.2008.01.03718295557
]Search in Google Scholar
[
118. Legrand T, Chhun S, Rey E, Blanchet B, Zahar JR, Lanternier F, et al. Simultaneous determination of three carbapenem antibiotics in plasma by HPLC with ultraviolet detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2008;875(2):551-6.10.1016/j.jchromb.2008.09.02018848512
]Search in Google Scholar
[
119. Nemutlu E, Kir S, Katlan D, Beksaç MS. Simultaneous multiresponse optimization of an HPLC method to separate seven cephalosporins in plasma and amniotic fluid: application to validation and quantification of cefepime, cefixime and cefoperazone. Talanta. 2009;80(1):117-26.10.1016/j.talanta.2009.06.03419782200
]Search in Google Scholar
[
120. Verdier MC, Tribut O, Tattevin P, Le Tulzo Y, Michelet C, Bentué-Ferrer D. Simultaneous determination of 12 beta-lactam antibiotics in human plasma by high-performance liquid chromatography with UV detection: application to therapeutic drug monitoring. Antimicrob Agents Chemother. 2011;55(10):4873-9.10.1128/AAC.00533-11318701321788467
]Search in Google Scholar
[
121. Dailly E, Bouquié R, Deslandes G, Jolliet P, Le Floch R. A liquid chromatography assay for a quantification of doripenem, ertapenem, imipenem, meropenem concentrations in human plasma: application to a clinical pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2011;879(15-16):1137-42.10.1016/j.jchromb.2011.03.03821474395
]Search in Google Scholar
[
122. Briscoe SE, McWhinney BC, Lipman J, Roberts JA, Ungerer JP. A method for determining the free (unbound) concentration of ten beta-lactam antibiotics in human plasma using high performance liquid chromatography with ultraviolet detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2012;907:178-84.10.1016/j.jchromb.2012.09.01623026224
]Search in Google Scholar
[
123. Veillette JJ, Winans SA, Forland SC, Maskiewicz VK. A simple and rapid RP-HPLC method for the simultaneous determination of piperacillin and tazobactam in human plasma. J Pharm Biomed Anal. 2016;131:80-86.10.1016/j.jpba.2016.08.01027529601
]Search in Google Scholar
[
124. Wicha SG, Kloft C. Simultaneous determination and stability studies of linezolid, meropenem and vancomycin in bacterial growth medium by high-performance liquid chromatography. J Chromatogr B Analyt Technol Biomed Life Sci. 2016;1028:242-248.10.1016/j.jchromb.2016.06.03327414982
]Search in Google Scholar
[
125. Pinder N, Brenner T, Swoboda S, Weigand MA, Hoppe- Tichy T. Therapeutic drug monitoring of beta-lactam antibiotics - Influence of sample stability on the analysis of piperacillin, meropenem, ceftazidime and flucloxacillin by HPLC-UV. J Pharm Biomed Anal. 2017;143:86-93.10.1016/j.jpba.2017.05.03728578254
]Search in Google Scholar
[
126. Sutherland CA, Nicolau DP. Development of an HPLC Method for the Determination of Meropenem/Vaborbactam in Biological and Aqueous Matrixes. J Chromatogr Sci. 2020;58(8):726-730.10.1093/chromsci/bmaa04132685976
]Search in Google Scholar
[
127. Milla P, Ferrari F, Muntoni E, Sartori M, Ronco C, Arpicco S. Validation of a simple and economic HPLC-UV method for the simultaneous determination of vancomycin, meropenem, piperacillin and tazobactam in plasma samples. J Chromatogr B Analyt Technol Biomed Life Sci. 2020;1148:122151.10.1016/j.jchromb.2020.12215132417718
]Search in Google Scholar
[
128. Casals G, Hernández C, Hidalgo S, Morales B, López- Púa Y, Castro P, et al. Development and validation of a UHPLC diode array detector method for meropenem quantification in human plasma. Clin Biochem. 2014;47(16-17):223-7.10.1016/j.clinbiochem.2014.08.00225128839
]Search in Google Scholar
[
129. Legrand T, Vodovar D, Tournier N, Khoudour N, Hulin A. Simultaneous Determination of Eight β-Lactam Antibiotics, Amoxicillin, Cefazolin, Cefepime, Cefotaxime, Ceftazidime, Cloxacillin, Oxacillin, and Piperacillin, in Human Plasma by Using Ultra-High-Performance Liquid Chromatography with Ultraviolet Detection. Antimicrob Agents Chemother. 2016;60(8):4734-42.10.1128/AAC.00176-16495819627216076
]Search in Google Scholar
[
130. Ferrone V, Cotellese R, Di Marco L, Bacchi S, Carlucci M, Cichella A, et al. Meropenem, levofloxacin and linezolid in human plasma of critical care patients: A fast semi-automated micro-extraction by packed sorbent UHPLC-PDA method for their simultaneous determination. J Pharm Biomed Anal. 2017;140:266-273.10.1016/j.jpba.2017.03.03528371721
]Search in Google Scholar
[
131. Ferrone V, Cotellese R, Carlucci M, Di Marco L, Carlucci G. Air assisted dispersive liquid-liquid microextraction with solidification of the floating organic droplets (AA-DLLME-SFO) and UHPLC-PDA method: Application to antibiotics analysis in human plasma of hospital acquired pneumonia patients. J Pharm Biomed Anal. 2018;151:266-273.10.1016/j.jpba.2017.12.03929413974
]Search in Google Scholar
[
132. Ferrone V, Cotellese R, Cichella A, Raimondi P, Carlucci M, Palumbo P, et al. Meropenem and ciprofloxacin in complicated gastric surgery for cancer patients: A simple SPE-UHPLC-PDA method for their determination in human plasma. Biomed Chromatogr. 2019;33(3):e4450.10.1002/bmc.445030513138
]Search in Google Scholar
[
133. Fage D, Deprez G, Fontaine B, Wolff F, Cotton F. Simultaneous determination of 8 beta-lactams and linezolid by an ultra-performance liquid chromatography method with UV detection and cross-validation with a commercial immunoassay for the quantification of linezolid. Talanta. 2021;221:121641.10.1016/j.talanta.2020.12164133076161
]Search in Google Scholar
[
134. Sime FB, Roberts MS, Roberts JA, Robertson TA. Simultaneous determination of seven β-lactam antibiotics in human plasma for therapeutic drug monitoring and pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci. 2014;960:134-44.10.1016/j.jchromb.2014.04.02924814000
]Search in Google Scholar
[
135. Parker SL, Pandey S, Sime FB, Lipman J, Roberts JA, Wallis SC. A validated LC-MSMS method for the simultaneous quantification of meropenem and vaborbactam in human plasma and renal replacement therapy effluent and its application to a pharmacokinetic study. Anal Bioanal Chem. 2019;411(29):7831-7840.10.1007/s00216-019-02184-431732787
]Search in Google Scholar
[
136. Parker SL, Pandey S, Sime FB, Stuart J, Lipman J, Roberts JA, et al. A validated LC-MS/MS method for the simultaneous quantification of the novel combination antibiotic, ceftolozane-tazobactam, in plasma (total and unbound), CSF, urine and renal replacement therapy effluent: application to pilot pharmacokinetic studies. Clin Chem Lab Med. 2020;59(5):921-933.10.1515/cclm-2020-119633554515
]Search in Google Scholar
[
137. Colin P, De Bock L, T’jollyn H, Boussery K, Van Bocxlaer J. Development and validation of a fast and uniform approach to quantify β-lactam antibiotics in human plasma by solid phase extraction-liquid chromatography- electrospray-tandem mass spectrometry. Talanta. 2013;103:285-93.10.1016/j.talanta.2012.10.04623200389
]Search in Google Scholar
[
138. Abdulla A, Bahmany S, Wijma RA, van der Nagel BCH, Koch BCP. Simultaneous determination of nine β-lactam antibiotics in human plasma by an ultrafast hydrophilic- interaction chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2017;1060:138-143.10.1016/j.jchromb.2017.06.01428618388
]Search in Google Scholar
[
139. Rigo-Bonnin R, Ribera A, Arbiol-Roca A, Cobo-Sacristán S, Padullés A, Murillo Ò, et al. Development and validation of a measurement procedure based on ultrahigh performance liquid chromatography-tandem mass spectrometry for simultaneous measurement of β-lactam antibiotic concentration in human plasma. Clin Chim Acta. 2017;468:215-224.10.1016/j.cca.2017.03.009
]Search in Google Scholar
[
140. Naicker S, Guerra Valero YC, Ordenez Meija JL, Lipman J, Roberts JA, Wallis SC, et al. A UHPLC-MS/MS method for the simultaneous determination of piperacillin and tazobactam in plasma (total and unbound), urine and renal replacement therapy effluent. J Pharm Biomed Anal. 2018;148:324-333.10.1016/j.jpba.2017.10.023
]Search in Google Scholar
[
141. Wise R, Logan M, Cooper M, Ashby JP, Andrews JM. Meropenem pharmacokinetics and penetration into an inflammatory exudate. Antimicrob Agents Chemother. 1990;34(8):1515-1517.10.1128/AAC.34.8.1515
]Search in Google Scholar
[
142. Leroy A, Fillastre JP, Borsa-Lebas F, Etienne I, Humbert G. Pharmacokinetics of meropenem (ICI 194,660) and its metabolite (ICI 213,689) in healthy subjects and in patients with renal impairment. Antimicrob Agents Chemother. 1992;36(12):2794e2798.10.1128/AAC.36.12.2794
]Search in Google Scholar
[
143. Chimata M, Nagase M, Suzuki Y, Shimomura M, Kakuta S. Pharmacokinetics of meropenem in patients with various degrees of renal function, including patients with end-stage renal disease. Antimicrob Agents Chemother. 1993;37(2):229-33.10.1128/AAC.37.2.229
]Search in Google Scholar
[
144. Bergogne-Berezin E, Muller-Serieys C, Aubier M, Dombret MC. Concentrations of meropenem in serum and in bronchial secretions in patients undergoing fiberoptic bronchoscopy. European Journal of Clinical Pharmacology. 1994;46(1):87-8.10.1007/BF00195922
]Search in Google Scholar
[
145. Byl B, Jacobs F, Roucloux I, de Franquen P, Cappello M, Thys JP. Penetration of meropenem in lung, bronchial mucosa, and pleural tissues. Antimicrob Agents Chemother. 1999;43(3):681-2.10.1128/AAC.43.3.681
]Search in Google Scholar
[
146. Mrestani Y, Neubert R, Nagel F. Capillary zone electrophoresis determination of meropenem in biological media using a high sensitivity cell. J Pharm Biomed Anal. 1999;20(6):899-903.10.1016/S0731-7085(99)00100-4
]Search in Google Scholar
[
147. Gáspár A, Karlos S, Andrási M, Klekner A. Capillary electrophoresis for the direct determination of cephalosporins in clinical samples. Chromatographia. 2002;56: S109-S114.10.1007/BF02494122
]Search in Google Scholar
[
148. Kitahashi T, Furuta I. Determination of meropenem by capillary electrophoresis using direct injection of serum. J. Chromatogr Sci. 2005;43(8):430-433.10.1093/chromsci/43.8.43016212785
]Search in Google Scholar
[
149. Andrási M, Gáspár A, Klekner A. Analysis of cephalosporins in bronchial secretions by capillary electrophoresis after simple pretreatment. J Chromatogr B Analyt Technol Biomed Life Sci. 2007;846(1-2):355-8.10.1016/j.jchromb.2006.08.025
]Search in Google Scholar
[
150. Al-Attas A, Nasr JJ, El-Enany N, Belal F. A green capillary zone electrophoresis method for the simultaneous determination of piperacillin, tazobactam and cefepime in pharmaceutical formulations and human plasma. Biomed Chromatogr. 2015;29(12):1811-8.10.1002/bmc.3500
]Search in Google Scholar
[
151. Carlucci G, Mazzeo P, Bologna M. Imipenem in biological fluids analysed by derivative UV-spectrometry. J Pharmaceut Biomed. 1991; 9(10-12):1169–1172.10.1016/0731-7085(91)80062-E
]Search in Google Scholar
[
152. Jhankal KK, Sharma DK. Electrochemical studies of meropenem at glassy carbon electrode and its direct determination in human plasma by square wave anodic adsorptive stripping voltammetry. Chem Sci Trans. 2016;5(4):1008–1018.
]Search in Google Scholar
[
153. Merola G, Martini E, Tomassetti M, Campanella L. Simple and suitable immunosensor for β-lactam antibiotics analysis in real matrixes: milk, serum, urine. J Pharm Biomed Anal. 2015;106:186-96.10.1016/j.jpba.2014.08.00525178531
]Search in Google Scholar
[
154. Farrell CD, Rowell FJ, Cumming RH. A rapid florescence ELISA for ceftazidime. Anal Proc. 1995;32:205–206.10.1039/ai9953200205
]Search in Google Scholar
[
155. Cullmann W, Dick W, Edelmann M. An enzymatic assay for monitoring serum, cerebrospinal fluid, and urine concentration of beta-lactam antibiotics. J Clin Chem Clin Biochem. 1985;23(3):151-6.
]Search in Google Scholar
[
156. Bax RP, Bastain W, Featherstone A, Wilkinson DM, Hutchison M, Haworth SJ. The pharmacokinetics of meropenem in volunteers. J Antimicrob Chemother. 1989;24 Suppl A:311-20.10.1093/jac/24.suppl_A.3112808215
]Search in Google Scholar
[
157. Burman LA, Nilsson-Ehle I, Hutchison M, Haworth SJ, Norrby SR. Pharmacokinetics of meropenem and its metabolite ICI 213,689 in healthy subjects with known renal metabolism of imipenem. J Antimicrob Chemother. 1991;27(2):219-24.10.1093/jac/27.2.2192055812
]Search in Google Scholar
[
158. Nilsson-Ehle I, Hutchison M, Haworth SJ, Norrby SR. Pharmacokinetics of meropenem compared to imipenem-cilastatin in young, healthy males. Eur J Clin Microbiol Infect Dis. 1991;10(2):85-8.10.1007/BF019644131864280
]Search in Google Scholar
[
159. Granai F, Smart HL, Triger DR. A study of the penetration of meropenem into bile using endoscopic retrograde cholangiography. J Antimicrob Chemother. 1992;29(6):711-8.10.1093/jac/29.6.7111506351
]Search in Google Scholar
[
160. Harrison MP, Haworth SJ, Moss SR, Wilkinson DM, Featherstone A. The disposition and metabolic fate of 14C-meropenem in man. Xenobiotica. 1993;23(11):1311-23.10.3109/004982593090594418310714
]Search in Google Scholar
[
161. Bedikian A, Okamoto MP, Nakahiro RK, Farino J, Heseltine PN, Appleman MD, ET AL. Pharmacokinetics of meropenem in patients with intra-abdominal infections. Antimicrob Agents Chemother. 1994;38(1):151-4.10.1128/AAC.38.1.151
]Search in Google Scholar
[
162. Lovering AM, Vickery CJ, Watkin DS, Leaper D, McMullin CM, White LO, ET AL. The pharmacokinetics of meropenem in surgical patients with moderate or severe infections. J Antimicrob Chemother. 1995;36(1):165-72.10.1093/jac/36.1.165
]Search in Google Scholar
[
163. Kelly HC, Hutchison M, Haworth SJ. A comparison of the pharmacokinetics of meropenem after administration by intravenous injection over 5 min and intravenous infusion over 30 min. J Antimicrob Chemother. 1995;36 Suppl A:35-41.10.1093/jac/36.suppl_A.35
]Search in Google Scholar
[
164. Hutchison M, Faulkner KL, Turner PJ, Haworth SJ, Sheikh W, Nadler H, Pitkin DH. A compilation of meropenem tissue distribution data. J Antimicrob Chemother. 1995;36 Suppl A:43-56.10.1093/jac/36.suppl_A.43
]Search in Google Scholar
[
165. Lee HS, Shim HO, Yu SR. High-performance liquid chromatographic determination of meropenem in rat plasma using column-switching. Chromatographia. 1996;42(7):405–408.10.1007/BF02272131
]Search in Google Scholar
[
166. Dupuis A, Minet P, Couet W, Courtois P, Bouquet S. Rapid and sensitive determination of meropenem in rat plasma by high performance liquid chromatography. Journal of Liquid Chromatography & Related Technologies. 1998;21(16):2549–2560.10.1080/10826079808003598
]Search in Google Scholar
[
167. Ip M, Au C, Cheung SW, Chan CY, Cheng AF. A rapid high-performance liquid chromatographic assay for cefepime, cefpirome and meropenem. J Antimicrob Chemother. 1998;42(1):121-3.10.1093/jac/42.1.121
]Search in Google Scholar
[
168. Allegranzi B, Cazzadori A, Di Perri G, Bonora S, Berti M, Franchino L, et al. Concentrations of single-dose meropenem (1 g iv) in bronchoalveolar lavage and epithelial lining fluid. Journal of Antimicrobial Chemotherapy. 2000;46(2):319-22.10.1093/jac/46.2.319
]Search in Google Scholar
[
169. Ehrlich M, Daschner FD, Kümmerer K. Rapid antibiotic drug monitoring: meropenem and ceftazidime determination in serum and bronchial secretions by high-performance liquid chromatography-integrated sample preparation. J Chromatogr B Biomed Sci Appl. 2001;751(2):357-63.10.1016/S0378-4347(00)00504-1
]Search in Google Scholar
[
170. Robatel C, Decosterd LA, Biollaz J, Eckert P, Schaller MD, Buclin T. Pharmacokinetics and dosage adaptation of meropenem during continuous venovenous hemodiafiltration in critically ill patients. J Clin Pharmacol. 2003;43(12):1329-40.10.1177/009127000326028614615469
]Search in Google Scholar
[
171. Legrand T, Chhun S, Rey E, Blanchet B, Zahar JR, Lanternier F, et al. Simultaneous determination of three carbapenem antibiotics in plasma by HPLC with ultraviolet detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2008;875(2):551-6.10.1016/j.jchromb.2008.09.02018848512
]Search in Google Scholar
[
172. Delattre IK, Musuamba FT, Verbeeck RK, Dugernier T, Spapen H, Laterre PF, et al. Empirical models for dosage optimization of four beta-lactams in critically ill septic patients based on therapeutic drug monitoring of amikacin. Clin Biochem. 2010;43(6):589-98.10.1016/j.clinbiochem.2009.12.00720036226
]Search in Google Scholar
[
173. Kameda K, Ikawa K, Ikeda K, Morikawa N, Nakashima A, Ohge H, et al. HPLC method for measuring meropenem and biapenem concentrations in human peritoneal fluid and bile: application to comparative pharmacokinetic investigations. Journal of Chromatographic Science. 2010;48(5):406–411.10.1093/chromsci/48.5.40620515537
]Search in Google Scholar
[
174. Cherkashina K, Lebedinets S, Pochivalov A, Lezov A, Vakh C, Bulatov A. Homogeneous liquid-liquid microextraction based on primary amine phase separation: A novel approach for sample pretreatment. Anal Chim Acta. 2019;1074:117-122.10.1016/j.aca.2019.04.07031159931
]Search in Google Scholar
[
175. Simon P, Petroff D, Busse D, Heyne J, Girrbach F, Dietrich A, et al. Meropenem Plasma and Interstitial Soft Tissue Concentrations in Obese and Nonobese Patients- A Controlled Clinical Trial. Antibiotics (Basel). 2020;9(12):931.10.3390/antibiotics9120931776738533371322
]Search in Google Scholar
[
176. Nau R, Lassek C, Kinzig-Schippers M, Thiel A, Prange HW, Sörgel F. Disposition and elimination of meropenem in cerebrospinal fluid of hydrocephalic patients with external ventriculostomy. Antimicrob Agents Chemother. 1998;42(8):2012-6.10.1128/AAC.42.8.20121057259687399
]Search in Google Scholar
[
177. Conte JE Jr, Golden JA, Kelley MG, Zurlinden E. Intrapulmonary pharmacokinetics and pharmacodynamics of meropenem. Int J Antimicrob Agents. 2005;26(6):449-56.10.1016/j.ijantimicag.2005.08.01516280244
]Search in Google Scholar
[
178. Krueger WA, Bulitta J, Kinzig-Schippers M, Landersdorfer C, Holzgrabe U, Naber KG, et al. Evaluation by monte carlo simulation of the pharmacokinetics of two doses of meropenem administered intermittently or as a continuous infusion in healthy volunteers. Antimicrob Agents Chemother. 2005;49(5):1881-9.10.1128/AAC.49.5.1881-1889.2005108763815855510
]Search in Google Scholar
[
179. Ahsman MJ, Wildschut ED, Tibboel D, Mathot RA. Microanalysis of beta-lactam antibiotics and vancomycin in plasma for pharmacokinetic studies in neonates. Antimicrob Agents Chemother. 2009;53(1):75-80.10.1128/AAC.00636-08261215818955527
]Search in Google Scholar
[
180. Cohen-Wolkowiez M, White NR, Bridges A, Benjamin DK Jr, Kashuba AD. Development of a liquid chromatography- tandem mass spectrometry assay of six antimicrobials in plasma for pharmacokinetic studies in premature infants. J Chromatogr B Analyt Technol Biomed Life Sci. 2011;879(30):3497-506.10.1016/j.jchromb.2011.09.031321040521983195
]Search in Google Scholar
[
181. Carlier M, Stove V, Roberts JA, Van de Velde E, De Waele JJ, Verstraete AG. Quantification of seven β-lactam antibiotics and two β-lactamase inhibitors in human plasma using a validated UPLC-MS/MS method. Int J Antimicrob Agents. 2012;40(5):416-22.10.1016/j.ijantimicag.2012.06.02222884857
]Search in Google Scholar
[
182. Rigo-Bonnin R, Juvany-Roig R, Leiva-Badosa E, Sabater- Riera J, Pérez-Fernández XL, Cárdenas-Campos P, et al. Measurement of meropenem concentration in different human biological fluids by ultra-performance liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem. 2014;406(20):4997-5007.10.1007/s00216-014-7910-924879538
]Search in Google Scholar
[
183. Ferrari D, Ripa M, Premaschi S, Banfi G, Castagna A, Locatelli M. LC-MS/MS method for simultaneous determination of linezolid, meropenem, piperacillin and teicoplanin in human plasma samples. J Pharm Biomed Anal. 2019;169:11-18.10.1016/j.jpba.2019.02.03730826487
]Search in Google Scholar
[
184. Rehm S, Rentsch KM. HILIC LC-MS/MS method for the quantification of cefepime, imipenem and meropenem. J Pharm Biomed Anal. 2020;186:113289.10.1016/j.jpba.2020.11328932428767
]Search in Google Scholar
[
185. Krnáč D, Reiffová K, Rolinski B. A new HPLC-MS/MS analytical method for quantification of tazobactam, piperacillin, and meropenem in human plasma. J Sep Sci. 2021;44(14):2744-2753.10.1002/jssc.20210006733988308
]Search in Google Scholar
[
186. Chou YW, Yang YH, Chen JH, Kuo CC, Chen SH. Quantification of meropenem in plasma and cerebrospinal fluid by micellar electrokinetic capillary chromatography and application in bacterial meningitis patients. Journal of chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 2007;856(1-2):294-301.10.1016/j.jchromb.2007.06.01517625990
]Search in Google Scholar
[
187. Christensson BA, Nilsson-Ehle I, Hutchison M, Haworth SJ, Oqvist B, Norrby SR. Pharmacokinetics of meropenem in subjects with various degrees of renal impairment. Antimicrob Agents Chemother. 1992;36(7):1532-1537.10.1128/AAC.36.7.15321916161510451
]Search in Google Scholar
[
188. Martens-Lobenhoffer J, Bode-Böger SM. Quantification of meropenem in human plasma by HILIC - tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2017;1046:13-17.10.1016/j.jchromb.2017.01.01628126443
]Search in Google Scholar
[
189. Food and Drug Administration. Guidance for industry on bioanalytical method validation. Rockville, MD: U.S. Department of Health and Human Services 2001. Available at: https://www.fda.gov/files/drugs/published/Bioanalytical-Method-Validation-Guidance-for-Industry.pdf. [cited Nov 6 2021].
]Search in Google Scholar
[
190. Balouiri M, Sadiki M, Ibnsouda SK. Methods for in vitro evaluating antimicrobial activity: A review. J Pharm Anal. 2016;6(2):71-79.10.1016/j.jpha.2015.11.005576244829403965
]Search in Google Scholar
