[
1. Osuka S, Nakanishi N, Murase T, Nakamura T, Goto M, Iwase A, et al. Animal models of polycystic ovary syn-drome: a review of hormone-induced rodent models focused on hypothalamus-pituitary-ovary axis and neuro-peptides. Reprod Med Biol. 2019, 18:151–60. doi: 10.1002/rmb2.1226210.1002/rmb2.12262
]Search in Google Scholar
[
2. Paixão L, Ramos RB, Lavarda A et al. Animal models of hyperandrogenism and ovarian morphology changes as features of polycystic ovary syndrome: a systematic review. Reprod Biol Endocrinol 15, 12 (2017). https://doi.org/10.1186/s12958-017-0231-z10.1186/s12958-017-0231-z
]Search in Google Scholar
[
3. Haning RV Jr, Hua JJ, Hackett RJ, Wheeler CA, Frish-man GN, Seifer DB, et al. Dehydroepiandrosterone sul-fate and anovulation increase serum inhibin and affect follicular function during administration of gonadotro-pins. J Clin Endocrinol Metab 1994; 78:145–9.
]Search in Google Scholar
[
4. Azziz R, Carmina E, Dewailly D, Diamanti-Kandarakis E, EscobarMorreale HF, Futterweit W, et al. The Andro-gen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report. Fertil Steril 2009; 91:456–88.10.1016/j.fertnstert.2008.06.035
]Search in Google Scholar
[
5. Noroozzadeh M, Behboudi-Gandevani S, Zadeh-Vakili A, Ramezani TF. Hormone-induced rat model of poly-cystic ovary syndrome: A systematic review. Life Sci. 2017;191:259-272.10.1016/j.lfs.2017.10.020
]Search in Google Scholar
[
6. Knudsen JF, Costoff A, Mahesh VB. Dehydroepian drosterone-induced polycystic ovaries and acyclicity in the rat. Fertil Steril 1975; 26:807–17.10.1016/S0015-0282(16)41297-5
]Search in Google Scholar
[
7. Quandt LM, Hutz RJ. Induction by estradiol-17 beta of polycystic ovaries in the guinea pig. Biol Reprod 1993; 48:1088–94.10.1095/biolreprod48.5.10888481473
]Search in Google Scholar
[
8. Takeo Y. Influence of continuous illumination on es-trous cycle of rats: time course of changes in levels of gonadotropins and ovarian steroids until occurrence of persistent estrus. Neuroendocrinology 1984; 39:97–104.10.1159/0001239646433219
]Search in Google Scholar
[
9. Chung, F. F., Yao, C. C., and Wan, G. H. (2005). The associations between menstrual function and life style/working conditions among nurses in Taiwan. J. Occup. Health. 47, 149–156. doi: 10.1539/joh.47.14910.1539/joh.47.14915824480
]Search in Google Scholar
[
10. Mesbah F, Moslem M, Vojdani Z, Mirkhani H. Does metformin improve in vitro maturation and ultrastruc-ture of oocytes retrieved from estradiol valerate polycys-tic ovary syndrome-induced rats. J Ovarian Res. 2015; 8:1-10.10.1186/s13048-015-0203-x465031826577050
]Search in Google Scholar
[
11. Franks S. Can animal models of PCOS help in the direc-tion of early and effective therapeutic intervention in women with the syndrome? Endocrinology. 2015; doi: 10.1210/sr.2015-1420.
]Search in Google Scholar
[
12. Malikueo M, Benrick A, Stener-Victorin E. Rodent models of polycystic ovary syndrome: phenotypic presentation, pathophysiology and effects of different interventions. Semin Reprod Med. 2014; doi: 10.1055/s-0034-1371090.10.1055/s-0034-137109024715513
]Search in Google Scholar
[
13. Dumesic DA, Oberfield SE, Stener-Victorin E, Mar-shall JC, Laven JS, Legro RS. Scientific statement on the diagnostic criteria, epidemiology, pathophysiology, and molecular genetics of polycystic ovary syndrome. Endocr Rev. 2015; 36(5):487-525.10.1210/er.2015-1018
]Search in Google Scholar
[
14. Gorsic LK, Dapas M, Legro RS, Hayes MG, Ur-banek M. Functional genetic variation in the anti-Mül-lerian hormone pathway in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2019; 104(7):2855-74.10.1210/jc.2018-02178
]Search in Google Scholar
[
15. Gorsic LK, Kosova G, Werstein B, et al. Pathogenic anti-Müllerian hormone variants in polycystic ovary syndrome. J Clin Endocrinol Metab. 2017; 102(8):2862-72.10.1210/jc.2017-00612
]Search in Google Scholar
[
16. Dapas M, Sisk R, Legro RS, Urbanek M, Dunaif A, Hayes MG. Family-based quantitative trait metaanaly-sis implicates rare noncoding variants in DENND1A in polycystic ovary syndrome. J Clin Endocrinol Metab. 2019; 104(9):3835-50.10.1210/jc.2018-02496
]Search in Google Scholar
[
17. Crisosto N, Codner E, Maliqueo M, et al. AntiMüllerian hormone levels in peripubertal daughters of women with polycystic ovary syndrome. J Clin Endo-crinol Metab. 2007; 92(7):2739-43.10.1210/jc.2007-0267
]Search in Google Scholar
[
18. Crisosto N, Ladrón de Guevara A, Echiburú B, et al. Higher luteinizing hormone levels associated with an-timüllerian hormone in postmenarchal daughters of women with polycystic ovary syndrome. Fertil Steril. 2019; 111(2):381-8.10.1016/j.fertnstert.2018.10.011
]Search in Google Scholar
[
19. Walters KA, Allan CM, Handelsman DJ. Rodent models for human polycystic ovary syndrome. Biol Reprod. 2012 May 10;86(5):149, 1-12. doi: 10.1095/biolreprod. 111.097808. PMID: 22337333.
]Search in Google Scholar
[
20. Sabuncu T, Vural H, Harma M, Harma M. Oxidative stress in polycystic ovary syndrome and its contribution to the risk of cardiovascular disease. Clin Biochem. 2001 Jul;34(5):407-13. doi: 10.1016/s0009-9120(01)00245-4. PMID: 11522279.10.1016/S0009-9120(01)00245-4
]Search in Google Scholar
[
21. Duleba AJ, Dokras A. Is PCOS an inflammatory pro-cess? Fertil Steril. 2012 Jan;97(1):7-12. doi: 10.1016/j.fertnstert.2011.11.023. PMID: 22192135; PMCID: PMC3245829.10.1016/j.fertnstert.2011.11.023324582922192135
]Search in Google Scholar
[
22. Fenkci V, Fenkci S, Yilmazer M, Serteser M. Decreased total antioxidant status and increased oxidative stress in women with polycystic ovary syndrome may contribute to the risk of cardiovascular disease. Fertil Steril. 2003 Jul;80(1):123-127. DOI: 10.1016/s0015-0282(03)005 71-5.
]Search in Google Scholar
[
23. Colín-González AL, Santana RA, Silva-Islas CA, Chánez-Cárdenas ME, Santamaría A, Maldonado PD. The antioxidant mechanisms underlying the aged garlic extract- and S-allylcysteine-induced protection. Oxid Med Cell Longev. 2012;2012:907162. doi: 10.1155/2012/907162. Epub 2012 May 17. PMID: 22685624; PMCID: PMC3363007.10.1155/2012/907162336300722685624
]Search in Google Scholar
[
24. Baillargeon JP, Nestler JE. Commentary: polycystic ovary syndrome: a syndrome of ovarian hypersensitivity to insulin? J Clin Endocrinol Metab. 2006; 91(1):22-4.10.1210/jc.2005-1804384653216263814
]Search in Google Scholar
[
25. Nestler JE, Powers LP, Matt DW, et al. A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome. J Clin Endocrinol Metab.1991; 72(1):83-9.10.1210/jcem-72-1-83
]Search in Google Scholar
[
26. Dahlgren E, Janson PO. Polycystic ovary syndrome-long-term metabolic consequences. Int J Gynaecol Ob-stet. 1994 Jan;44(1):3-8. doi: 10.1016/0020-7292(94)90015-9. PMID: 7907056.10.1016/0020-7292(94)90015-9
]Search in Google Scholar
[
27. Roy S, Mahesh VB, Greenblatt RB. Effect of dehydroe-piandrosterone and delta4-androstenedione on the repro-ductive organs of female rats: production of cystic changes in the ovary. Nature 1962; 196:42–3.10.1038/196042a0
]Search in Google Scholar
[
28. Wang D, Wang W, Liang Q, et al. DHEA-induced ovar-ian hyper-fibrosis is mediated by TGF-β signaling path-way. J Ovarian Res. 2018; 11:1-11.10.1186/s13048-017-0375-7
]Search in Google Scholar
[
29. Liu W, Liu W, Fu Y, Wang Y, Zhang Y. BakFoong pills combined with metformin in the treatment of a polycys-tic ovarian syndrome rat model. Oncol Lett. 2015;10:1819-182510.3892/ol.2015.3466
]Search in Google Scholar
[
30. Jang M, Lee MJ, Lee JM, et al. Oriental medicine Kyung-Ok-Ko pre- vents and alleviates dehydroepi-androsterone-induced polycystic ovarian syndrome in rats. PLoS ONE. 2014; 9:e87623.10.1371/journal.pone.0087623
]Search in Google Scholar
[
31. Cussons AJ, Watts GF, Burke V, Shaw JE, Zimmet PZ, Stuckey BG. Cardiometabolic risk in polycystic ovary syndrome: a comparison of different approaches to de-fining the metabolic syndrome. Hum Reprod 2008;23: 2352–810.1093/humrep/den263
]Search in Google Scholar
[
32. Trivax B, Azziz R. Diagnosis of polycystic ovary syn-drome. ClinObstetGynecol2007; 50:168–77.10.1097/GRF.0b013e31802f351b
]Search in Google Scholar
[
33. Apter D, Butzow T, Laughlin GA, Yen SS. Accelerated 24-hour luteinizing hormone pulsatile activity in adoles-cent girls with ovarian hyperandrogenism: relevance to the developmental phase of polycystic ovarian syn-drome. J Clin Endocrinol Metab 1994;79:119–25
]Search in Google Scholar
[
34. Anderson E, Lee GY, O’Brien K. Polycystic ovarian condition in the dehydroepiandrosterone-treated rat model: hyperandrogenism and the resumption of meiosis are major initial events associated with cystogenesis of antral follicles. Anat Rec 1997; 249:44–53.10.1002/(SICI)1097-0185(199709)249:1<44::AID-AR6>3.0.CO;2-F
]Search in Google Scholar
[
35. Misugi T, Ozaki K, El Beltagy K, Tokuyama O, Honda K, Ishiko O. Insulin-lowering agents inhibit synthesis of testosterone in ovaries of DHEA-induced PCOS rats. Gynecol Obstet Invest. 2006;61(4):208-15. doi: 10.1159/000091496. Epub 2006 Feb 13. PMID: 16479139.10.1159/000091496
]Search in Google Scholar
[
36. Brawer JR, Munoz M, Farookhi R. Development of the polycystic ovarian condition (PCO) in the estradiol val-erate-treated rat. Biol Reprod. 1986; 35:647-655.10.1095/biolreprod35.3.6473098314
]Search in Google Scholar
[
37. Seow KM, Ting CH, Huang SW, Ho LT, Juan CC. The use of dehydroepiandrosterone-treated rats is not a good animal model for the study of metabolic abnormalities in polycystic ovary syndrome. Taiwan J Obstet Gynecol. 2018 Oct;57(5):696-704. doi: 10.1016/j.tjog.2018.08. 015. PMID: 30342654.
]Search in Google Scholar
[
38. Zhang H, Yi M, Zhang Y, Jin H, Zhang W, Yang J, Yan L, Li R, Zhao Y, Qiao J. High-fat diets exaggerate endo-crine and metabolic phenotypes in a rat model of DHEA-induced PCOS. Reproduction. 2016 Apr;151(4):431-41. doi: 10.1530/REP-15-0542. Epub 2016 Jan 26. PMID: 2681421010.1530/REP-15-054226814210
]Search in Google Scholar
[
39. Beloosesky R, Gold R, Almog B, Sasson R, Dantes A, Land-Bracha A, et al. Induction of polycystic ovary by testosterone in immature female rats: modulation of apoptosis and attenuation of glucose/insulin ratio. Int J Mol Med 2004; 14:207–15.10.3892/ijmm.14.2.20715254767
]Search in Google Scholar
[
40. Wu C, Lin F, Qiu S, Jiang Z. The characterization of obese polycystic ovary syndrome rat model suitable for exercise intervention. PLoS One. 2014 Jun 6;9(6):e99155. doi: 10.1371/journal.pone.0099155. PMID: 24905232; PMCID: PMC4048306.10.1371/journal.pone.0099155404830624905232
]Search in Google Scholar
[
41. Kalhori Z, Soleimani Mehranjani M, Azadbakht M, Shariaatzadeh MA. Ovary stereological features and se-rum biochemical factors following induction of polycys-tic ovary syndrome with testosterone enanthate in mice: An experimental study. Int J Reprod Biomed. 2018 Apr;16(4):267-274. PMID: 29942935; PMCID: PMC6004592.10.29252/ijrm.16.4.267
]Search in Google Scholar
[
42. Ota H, Fukushima M, Maki M. Endocrinological and histological aspects of the process of polycystic ovary formation in the rat treated with testosterone propionate. Tohoku J Exp Med 1983; 140:121–31.10.1620/tjem.140.1216612716
]Search in Google Scholar
[
43. Mannerås L, Cajander S, Holmäng A, et al. A new rat model exhibiting both ovarian and metabolic character-istics of polycystic ovary syndrome. Endocrinology. 2007; 148:3781-91.10.1210/en.2007-016817495003
]Search in Google Scholar
[
44. Keller J, Mandala M, Casson P, Osol G. Endothelial dys-function in a rat model of PCOS: Evidence of increased vasoconstrictor prostanoid activity. Endocrinology. 2011; 152:4927-36.10.1210/en.2011-142422028445
]Search in Google Scholar
[
45. Liu JH, Garzo G, Morris S, Stuenkel C, Ulmann A, Yen SS. Disruption of follicular maturation and delay of ov-ulation after administration of the antiprogesterone RU486. J Clin Endocrinol Metab 1987; 65:1135–40.10.1210/jcem-65-6-11352824550
]Search in Google Scholar
[
46. Ruiz A, Aguilar R, Tebar AM, Gaytan F, Sanchez-Cri-ado JE. RU486-treated rats show endocrine and morpho-logical responses to therapies analogous to responses of women with polycystic ovary syndrome treated with similar therapies. Biol Reprod 1996; 55:1284–91.10.1095/biolreprod55.6.12848949885
]Search in Google Scholar
[
47. Corbin CJ, Trant JM, Walters KW, Conley AJ. Changes in testosterone metabolism associated with the evolution of placental and gonadal isozymes of porcine aromatase cytochrome P450. Endocrinology 1999; 140:5202–10.10.1210/endo.140.11.714010537150
]Search in Google Scholar
[
48. Sommers SC. Polycystic ovaries revisited. In: Fenoglio CM, Wolff M, editors. Progress in surgical pathology. New York: Masson Publishing; 1980:221–32.
]Search in Google Scholar
[
49. Erickson GE, Yen SS. The polycystic ovary syndrome. In: Adashi EY, Leung PCK, editors. The ovary. New York: Raven Press; 1993:561–79.
]Search in Google Scholar
[
50. Kondo M, Osuka S, Iwase A, Nakahara T, Saito A, Bayasula, Nakamura T, Goto M, Kotani T, Kikkawa F. Increase of kisspeptin-positive cells in the hypothalamus of a rat model of polycystic ovary syndrome. Metab Brain Dis. 2016 Jun;31(3):673-81. doi: 10.1007/s11011-016-9807-0. Epub 2016 Feb 11. PMID: 26864582.10.1007/s11011-016-9807-026864582
]Search in Google Scholar
[
51. Sánchez-Criado JE, Sánchez A, Ruiz A, Gaytán F. En-docrine and morphological features of cystic ovarian condition in antiprogesterone RU486-treated rats. Acta Endocrinol (Copenh). 1993 Sep;129(3):237-45. doi: 10.1530/acta.0.1290237. PMID: 8212989.10.1530/acta.0.12902378212989
]Search in Google Scholar
[
52. Simard M, Brawer JR, Farookhi R. An intractable, ovary-independent impairment in hypothalamo-pituitary function in the estradiol-valerate-induced polycystic ovarian condition in the rat. Biol Reprod. 1987 Jun;36(5):1229-37. doi: 10.1095/biolreprod36.5.1229. PMID: 3113503.)10.1095/biolreprod36.5.12293113503
]Search in Google Scholar
[
53. Dikmen A, Ergenoglu AM, Yeniel AO, Dilsiz OY, Er-can G, Yilmaz H. Evaluation of glycemic and oxida-tive/antioxidative status in the estradiol valerate-induced PCOS model of rats. Eur J Obstet Gynecol Reprod Biol. 2012 Jan;160(1):55-9. doi: 10.1016/j.ejogrb.2011.09.042. Epub 2011 Nov 8. PMID: 22071112.10.1016/j.ejogrb.2011.09.04222071112
]Search in Google Scholar
[
54. Linares R, Rosas G, Vieyra E, Ramírez DA, Velázquez DR, Espinoza JA, Morán C, Domínguez R, Morales-Ledesma L. In Adult Rats With Polycystic Ovarian Syn-drome, Unilateral or Bilateral Vagotomy Modifies the Noradrenergic Concentration in the Ovaries and the Ce-liac Superior Mesenteric Ganglia in Different Ways. Front Physiol. 2019 Oct 22;10:1309. doi: 10.3389/fphys.2019.01309. PMID: 31695622; PMCID: PMC6817458.10.3389/fphys.2019.01309681745831695622
]Search in Google Scholar
[
55. Schulster A, Farookhi R, Brawer JR. Polycystic ovarian condition in estradiol valerate-treated rats: spontaneous changes in characteristic endocrine features. Biol Re-prod. 1984; 31:587-93.10.1095/biolreprod31.3.5876435694
]Search in Google Scholar
[
56. Karimzadeh L, Nabiuni M, Sheikholeslami A, Irian S. Bee venom treatment reduced C-reactive protein and improved follicle quality in a rat model of estradiol val-erate-induced polycystic ovarian syn-drome. J Venom Anim Toxins Incl Trop Dis. 2012; 18:384-92.10.1590/S1678-91992012000400006
]Search in Google Scholar
[
57. Diamanti-Kandarakis E. Polycystic ovarian syndrome: pathophysiology, molecular aspects and clinical impli-cations. Expert Rev Mol Med 2008; 10:e3.10.1017/S146239940800059818230193
]Search in Google Scholar
[
58. Baravalle C, Salvetti NR, Mira GA, Pezzone N, Ortega HH. Microscopic characterization of follicular structures in letrozolee-induced polycystic ovarian syndrome in the rat. Arch Med Res. 2006; 37:830-39.10.1016/j.arcmed.2006.04.00616971221
]Search in Google Scholar
[
59. Maliqueo M, Sun M, Johansson J, et al. Continuous ad-ministration of a P450 aromatase inhibitor induces poly-cystic ovary syndrome with a metabolic and endocrine phenotype in female rats at adult age. Endocrinology. 2013; 154(1):434-45.10.1210/en.2012-169323183180
]Search in Google Scholar
[
60. Fulghesu AM, Angioni S, Frau E, Belosi C, Apa R, Mioni R, et al. Ultrasound in polycystic ovary syndrome—the measuring of ovarian stroma and rela-tionship with circulating androgens: results of a multi-centric study. Hum Reprod 2007; 22: 2501–8.10.1093/humrep/dem20217635847
]Search in Google Scholar
[
61. Kalsbeek, A., Fliers, E., Romijn, J. A., La Fleur, S. E., Wortel, J.,Bakker, O., Endert, E., and Buijs, R. M. (2001) The suprachiasmatic nucleus generates the diurnal changes in plasma leptin levels. Endocrinology 142, 2677–268510.1210/endo.142.6.819711356719
]Search in Google Scholar
[
62. Scheer, F. A., Kalsbeek, A., and Buijs, R. M. (2003) Car-diovascular control by the suprachiasmatic nucleus: neu-ral and neuroendocrine mechanisms in human and rat. Biol. Chem. 384,697–709
]Search in Google Scholar
[
63. Scheer, F. A., Ter Horst, G. J., van der Vliet, J., and Buijs, R. M.(2001) Physiological and anatomic evidence for regulation of the heart by suprachiasmatic nucleus in rats. Am. J. Physiol. Heart10.1152/ajpheart.2001.280.3.H139111179089
]Search in Google Scholar
[
64. Stener-Victorin E, Padmanabhan V, Walters KA, et al. Animal Models to Understand the Etiology and Patho-physiology of Polycystic Ovary Syndrome. Endocr Rev. 2020;41(4):538-576. doi:10.1210/endrev/bnaa01010.1210/endrev/bnaa010727970532310267
]Search in Google Scholar
[
65. Milosević V, Trifunović S, Sekulić M, Sosić-Jurjević B, Filipović B, Negić N, Nestorović N, Manojlović Stojanoski M, Starcević V. Chronic exposure to constant light affects morphology and secretion of adrenal zona fasciculata cells in female rats. Gen Physiol Biophys. 2005 Sep;24(3):299-309. PMID: 16308425
]Search in Google Scholar
[
66. Ryu Y, Kim SW, Kim YY, Ku SY. Animal Models for Human Polycystic Ovary Syndrome (PCOS) Focused on the Use of Indirect Hormonal Perturbations: A Review of the Literature. Int J Mol Sci. 2019 ;20(11):2720.10.3390/ijms20112720660035831163591
]Search in Google Scholar
[
67. Nestorović N, Ristić N, Ajdžanović V, Trifunović S, Milošević V. Morphological and Functional Changes of Pi-tuitary GH and PRL Cells Following Prolonged Expo-sure of Female Rats to Constant Light. Serbian Journal of Experimental and Clinical Research. 2021;0(010.2478/sjecr-2019-0063
]Search in Google Scholar
[
68. Meinhardt UJ, Ho KK. Modulation of growth hormone action by sex steroids. Clin Endocrinol (Oxf). 2006; 65(4): 413-2210.1111/j.1365-2265.2006.02676.x16984231
]Search in Google Scholar
[
69. Freeman ME, Kanyicska B, Lerant A, Nagy G. Prolac-tin: structure, function, and regulation of secretion. Physiol Rev. 2000; 80(4): 1523-63110.1152/physrev.2000.80.4.152311015620
]Search in Google Scholar
[
70. Baldissera SF, Motta LD, Almeida MC, Antunes-Ro-drigues J. Proposal of an experimental model for the study of polycystic ovaries. Braz J Med Biol Res. 1991;24(7):747-51. PMID: 1823293.
]Search in Google Scholar
[
71. Chu W, Zhai J, Xu J, et al. Continuous Light-Induced PCOS-Like Changes in Reproduction, Metabolism, and Gut Microbiota in Sprague-Dawley Rats. Front Microbiol. 2020;10:3145. Published 2020 Jan 21. doi:10.3389/fmicb.2019.0314510.3389/fmicb.2019.03145699011232038578
]Search in Google Scholar
[
72. Maganhin CC, Fuchs LF, Simões RS, Oliveira-Filho RM, de Jesus Simões M, Baracat EC, Soares JM Jr. Ef-fects of melatonin on ovarian follicles. Eur J Obstet Gynecol Reprod Biol. 2013 Feb;166(2):178-84. doi: 10.1016/j.ejogrb.2012.10.006. Epub 2012 Oct 24. PMID: 23102587.10.1016/j.ejogrb.2012.10.006
]Search in Google Scholar
[
73. Xuezhi K, Lina J, Xueyong S, “Manifestation of Hyper-androgenism in the Continuous Light Exposure-Induced PCOS Rat Model”, BioMed Res., vol. 2015, Article ID 943694, 9 pages, 2015. https://doi.org/10.1155/2015/94369410.1155/2015/943694
]Search in Google Scholar
[
74. Soule SG: Neuroendocrinology of the polycystic ovary syndrome. Baillieres Clin Endocrinol Metab. 1996, 10 (2): 205-219. 10.1016/S0950-351X(96)80071-110.1016/S0950-351X(96)80071-1
]Search in Google Scholar
[
75. Zhai, HL., Wu, H., Xu, H. et al. Trace glucose and lipid metabolism in high androgen and high-fat diet induced polycystic ovary syndrome rats. Reprod Biol Endocrinol 10, 5 (2012). https://doi.org/10.1186/1477-7827-10-510.1186/1477-7827-10-5327836522276997
]Search in Google Scholar
[
76. Roberts JS, Perets RA, Sarfert KS, Bowman JJ, Ozark PA, Whitworth GB, Blythe SN, Toporikova N. High-fat high-sugar diet induces polycystic ovary syndrome in a rodent model. Biol Reprod. 2017 Mar;96(3):551-562. doi: 10.1095/biolreprod.116.142786. Epub 2017 Jan 27. PMID: 28203719.10.1095/biolreprod.116.14278628203719
]Search in Google Scholar
[
77. Patel R, Shah G. High-fat diet exposure from pre-puber-tal age induces polycystic ovary syndrome (PCOS) in rats. Reproduction. 2018 Feb;155(2):141-151. doi: 10.1530/REP-17-0584. Epub 2017 Dec 1. PMID: 29196492.10.1530/REP-17-058429196492
]Search in Google Scholar
