<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><p>Lagochilascaris minor is the causative agent of human lagochilascariosis, a disease that affects the neck region causing abscesses with eggs, adult parasites and L3/L4 larvae within purulent exudates. Nowadays, mice are considered intermediary hosts for the parasite. In previous study we observed that A/J mice experimentally infected with Lagochilascaris minor showed higher survival ratios than B10.A mice. Now, we denoted that A/J mice (resistant to experimental infection) produced higher levels of IgM, IgG and IgA against the crude extract (excepted for IgM) and secreted/excreted antigens of the parasite; on the other hand, B10.A mice (susceptible to experimental infection) produced higher levels of IgE in the later period of the experimental infection than A/J infected mice.</p></abstract>

Lagochilascaris minor is the causative agent of human lagochilascariosis, a disease that affects the neck region causing abscesses with eggs, adult parasites and L3/L4 larvae within purulent exudates. Nowadays, mice are considered intermediary hosts for the parasite. In previous study we observed that A/J mice experimentally infected with Lagochilascaris minor showed higher survival ratios than B10.A mice. Now, we denoted that A/J mice (resistant to experimental infection) produced higher levels of IgM, IgG and IgA against the crude extract (excepted for IgM) and secreted/excreted antigens of the parasite; on the other hand, B10.A mice (susceptible to experimental infection) produced higher levels of IgE in the later period of the experimental infection than A/J infected mice.

Lagochilascaris minor: Specific antibodies are related with resistance to experimental infection in A/J strain of mice

Department of Microbiology, Immunology, Parasitology and Pathology, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Brazil

Helminthologia

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Lagochilascaris minor is the causative agent of human lagochilascariosis, a disease that affects the neck region causing abscesses with eggs, adult parasites...

Lagochilascaris minor: Specific antibodies are related with resistance to experimental infection in A/J strain of mice

Publié en ligne: 08 sept. 2011

Pages: 162 - 166

DOI: https://doi.org/10.2478/s11687-011-0024-4

Mots clés
B cells, Lagochilascaris minor, helminth, Immunoglobulin, serology

© 2011 Institute of Parasitology, SAS, Košice, Slovakia

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Lagochilascaris minor: Specific antibodies are related with resistance to experimental infection in A/J strain of mice

Publié en ligne: 08 sept. 2011

Pages: 162 - 166

DOI: https://doi.org/10.2478/s11687-011-0024-4

Mots clésB cells, Lagochilascaris minor, helminth, Immunoglobulin, serology

© 2011 Institute of Parasitology, SAS, Košice, Slovakia

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Mots clés
B cells, Lagochilascaris minor, helminth, Immunoglobulin, serology