Post-chemotherapy bone metastasis recurrence of colorectal adenocarcinoma - case report

One of the most common neoplasms in the world, ranking third, is the colorectal cancer. 96% of all cases of colorectal cancer are adenocarcinoma. The prognostic of this diagnostic is a bad one, with low 5-years survival rate. Although the most common locations for the metastases are the liver and the lungs, the bones can also be targeted (5.5%).

We present the case of a 65-year-old male who came to the hospital with pain and tumefaction at the right fibular head. After extensive clinical and paraclinical examinations, a biopsy was performed, at which stage the entire tumor was removed. The result was that of moderate differentiated adenocarcinoma. The patient was then further examined and a tumor was discovered at the sigmoid colon. The primary tumor was removed and the patient underwent oncological treatment. 2 years later, the patient returned with a recurrence of the bone metastasis. After a PET-CT that infirmed other metastases coupled with a satisfactory evolution of the primary tumor, the decision was made to amputate the knee above. Biopsy is an essential step that establishes the correct diagnostic and dictates the right choice of treatment solution. Counseling is also essential, so that the patient can choose and accept the best treatment option.