<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Left ventricular noncompaction is a rare structural cardiomyopathy that can occur isolated or in relationship with other conditions, mainly with musculoskeletal diseases or congenital heart defects. The association of left ventricular noncompaction and connective tissue disorders, including systemic lupus erythematosus, was scarcely described in the literature. Reported cases are, more likely, cardiomyopathies mimicking left ventricular noncompaction or transient left ventricular noncompaction with ventricular function improving after appropriate treatment.</p><p>We present the case of a 23-year-old woman admitted for cardiac evaluation because of ECG abnormalities observed during a routine check-up. Echocardiography showed severe systolic and diastolic dysfunction, diffuse hypokinesis and hypertrabeculation, suggestive of left ventricular non-compaction. Cardiac magnetic resonance imaging confirmed the diagnosis. She later presented with specific clinical and biological parameters and was diagnosed with systemic lupus erythematosus. Corticosteroid and hydroxychloroquine treatment induced general improvement of signs and symptoms, but no recovery of cardiac function.</p></abstract>

Left ventricular noncompaction is a rare structural cardiomyopathy that can occur isolated or in relationship with other conditions, mainly with musculoskeletal diseases or congenital heart defects. The association of left ventricular noncompaction and connective tissue disorders, including systemic lupus erythematosus, was scarcely described in the literature. Reported cases are, more likely, cardiomyopathies mimicking left ventricular noncompaction or transient left ventricular noncompaction with ventricular function improving after appropriate treatment.We present the case of a 23-year-old woman admitted for cardiac evaluation because of ECG abnormalities observed during a routine check-up. Echocardiography showed severe systolic and diastolic dysfunction, diffuse hypokinesis and hypertrabeculation, suggestive of left ventricular non-compaction. Cardiac magnetic resonance imaging confirmed the diagnosis. She later presented with specific clinical and biological parameters and was diagnosed with systemic lupus erythematosus. Corticosteroid and hydroxychloroquine treatment induced general improvement of signs and symptoms, but no recovery of cardiac function.

Left Ventricular noncompaction in a patient with systemic lupus erythematosus

“Carol Davila” University of Medicine and Pharmacy

Cardiology Department, “Colentina” Clinical Hospital

Internal Medicine Department, “Colentina” Clinical Hospital

CDPC Cardiology Laboratory, “Colentina” Clinical Hospital

Romanian Journal of Internal Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

{"article-title":"Left Ventricular noncompaction in a patient with systemic lupus erythematosus"}

Left ventricular noncompaction is a rare structural cardiomyopathy that can occur isolated or in relationship with other conditions, mainly with...

Left Ventricular noncompaction in a patient with systemic lupus erythematosus

Publié en ligne: 28 mars 2019

Pages: 78 - 82

Reçu: 11 oct. 2018

DOI: https://doi.org/10.2478/rjim-2018-0032

Mots clés
left ventricular noncompaction, LVNC, cardiomyopathy, systemic lupus erythematosus

© 2019 Mihaela Dobranici et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Left Ventricular noncompaction in a patient with systemic lupus erythematosus

Publié en ligne: 28 mars 2019

Pages: 78 - 82

Reçu: 11 oct. 2018

DOI: https://doi.org/10.2478/rjim-2018-0032

Mots clésleft ventricular noncompaction, LVNC, cardiomyopathy, systemic lupus erythematosus

© 2019 Mihaela Dobranici et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Mots clés
left ventricular noncompaction, LVNC, cardiomyopathy, systemic lupus erythematosus